Not yet recruitingPhase 3

AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

NCT07400107

What is this trial?

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Am I eligible?

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What's involved?

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Where and how to apply

Primary location

Encore Medical Research LLC

Hollywood, Florida, United States

+119 additional locations

Contact

Novo Nordisk

(+1) 866-867-7178 clinicaltrials@novonordisk.com

View on ClinicalTrials.gov

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Quick facts

Start date: 2026-05-20
Enrollment: 1,000 participants
Sponsor: Novo Nordisk A/S
Purpose: treatment

Locations (120)

Encore Medical Research LLCHollywood, Florida, United States
Optimal Research SitesOrange City, Florida, United States
Encore Medical Research of WestonWeston, Florida, United States
Endocrine Research Solutions, IncRoswell, Georgia, United States
Elite Clinical TrialsBlackfoot, Idaho, United States
Endo And Metab ConsRockville, Maryland, United States
Arcturus Healthcare, PLC.Troy, Michigan, United States
Velocity Clin Res, DallasDallas, Texas, United States
Consano Clinical Research, LLCShavano Park, Texas, United States
Selma Medical AssociatesWinchester, Virginia, United States
Centro de Investigaciones MetabólicasCapital Federal, Buenos Aires, Argentina
Centro Médico CIMELLanús Este, Buenos Aires, Argentina
Centro Médico Privado San Vicente DiabetesCórdoba, Argentina
Núcleo de Pesquisa Clínica do Rio Grande do Sul Ltda.Porto Alegre, Rio Grande do Sul, Brazil
i9 Pesquisas ClínicasCampinas, São Paulo, Brazil
CPQuali Pesquisa Clínica LtdaSão Paulo, São Paulo, Brazil
BR Trials - Ensaios Clínicos e Consultoria Ltda.São Paulo, São Paulo, Brazil
Dr. Tatyana Metalova - AIPSMCE EOODGotse Delchev, Bulgaria
Medical centre Zdrave 1 OODKozloduy, Bulgaria
UMHAT Pulmed OOD - Pazardzhik, Department of Internal DiseasesPazardzhik, Bulgaria
MHAT Heart and Brain EAD - Pleven, Endocrinology and Metabolic DiseasesPleven, Bulgaria
DCC I- Pleven EOOD EndocrinologyPleven, Bulgaria
MHAT Knyaginya Klementina - Sofia EADSofia, Bulgaria
MHAT Sveta Sofia EOOD, Department of Endocrinology and Metabolic diseasesSofia, Bulgaria
Acibadem City Clinic UMHAT Tokuda EAD, EndocrinologySofia, Bulgaria
USHATE Akad. Ivan Penchev EAD, Second Clinic of EndocrinologySofia, Bulgaria
Medical Institute of Ministry of interiorSofia, Bulgaria
Medical Centre - Clinic Nova EOODVarna, Bulgaria
Poliklinika Medikol ZagrebGrad Zagreb, Croatia
Opca bolnica KarlovacKarlovac, Croatia
Specijalna Bolnica za medicinsku rehabilitaciju Krapinske Toplice_EndocrinologyKrapinske Toplice, Croatia
Poliklinika SLAVONIJA OSIJEKOsijek, Croatia
Clinical Hospital Centre Rijeka_EndocrinologyRijeka, Croatia
General Hospital Dr. Josip Bencevic_Diabetic departmentSlavonski Brod, Croatia
Opca bolnica Varazdin_EndocrinologyVaraždin, Croatia
Poliklinika SolmedZagreb, Croatia
Herz- und Diabeteszentrum NRW - Bad OeynhausenBad Oeynhausen, Germany
Zentrum fuer klinische Studien Suedbrandenburg GmbHElsterwerda, Germany
Praxis am Markt Dr. BeckerEssen, Germany
MVZ im Altstadt-Carree Fulda GmbH - Zentrum für klinische StudienFulda, Germany
Diabetes-Zentrum-Wilhelmsburg GbRHamburg, Germany
Diabetologische Gemeinschaftspraxis Dr. Staudenmeyer und Dr. SchiwietzLingen, Germany
SMO.MD GmbH - Zentrum für klinische StudienMagdeburg, Germany
Institut für Diabetesforschung OsnabrückOsnabrück, Germany
ceda - Centrum für Diabetologie und Allgemeinmedizin PohlheimPohlheim, Germany
Forschungszentrum Ruhr KliFoCenter GmbH, KahrmannWitten, Germany
Debreceni EgyetemDebrecen, Hajdú-Bihar, Hungary
Komáromi Selye János KórházKomárom, Komárom-Esztergom, Hungary
Óbudai Egészségügyi CentrumBudapest, Pest County, Hungary
Borbánya Praxis E.Ü. Kft.Nyíregyháza, Szabolcs-Szatmar Varmegye, Hungary
Békés Vármegyei Központi KórházGyula, Hungary
Endolife Specialty HospitalsGuntur, Andhra Pradesh, India
Nirmal Hospital Pvt. Ltd.Surat, Gujarat, India
SSG Hospital, BarodaVadodara, Gujarat, India
Diacon Hospital Private LimitedBangalore, Karnataka, India
Lifecare Hospital and Research CentreBengaluru, Karnataka, India
Amrita Institute Of Medical Sciences & Research CentreKochi, Kerala, India
TOTALL Diabetes Hormone InstituteIndore, Madhya Pradesh, India
BSES MG hospitalMumbai, Maharashtra, India
Shalini Tai Meghe Hospital and Research CenterNagpur, Maharashtra, India
Chellaram Diabetes InstitutePune, Maharashtra, India
SMS Medical College & HospitalJaipur, Rajasthan, India
Diabetes, Thyroid and Endocrine CentreJaipur, Rajasthan, India
Arthur Asirvatham hospital,Madurai, Tamil Nadu, India
NIZAM'S Institute of Medical SciencesHyderabad, Telangana, India
IPGME&R and SSKM HospitalKolkata, West Bengal, India
Rajiv Gandhi Centre for Diabetes and Endocrinology, J.N Medical College, Aligarh Muslim UniversityAligarh, India
All India Institute of Medical Sciences (AIIMS)New Delhi, India
Jothydev's Diabetes & Research CenterThriruvananthapuram, India
Diseño y Planeación en Investigación Médica S.C.Guadalajara, Jalisco, Mexico
Alliance CEINV Salud S.A. de C.V.Monterrey, Nuevo León, Mexico
Centro de Estudios de Investigación Metabólicos y CardioCiudad Madero, Tamaulipas, Mexico
Gabinety Medyczne MATUSZEK Beata Matyjaszek-Matuszek Prywatna Praktyka SpecjalistycznaLublin, Lesser Poland Voivodeship, Poland
EKAMED sp. z o.o.Lublin, Lublin Voivodeship, Poland
Przychodnie Grudziadz Sp. z o. o.Grudziądz, Mazovian Voivodeship, Poland
Legeartis Poradnie Specjalistyczne Sp. z o.o.Bialystok, Podlaskie Voivodeship, Poland
NZOZ Specjalistyczny Osrodek Internistyczno-Diabetologiczny Małgorzata ArciszewskaBialystok, Poland
NZOZ Vita-Diabetica Malgorzata BuraczykBialystok, Poland
Centrum Kliniczno-Badawcze J.Brzezicki B.Gornikiewicz-Brzezicka Lekarze sp.p.Elblag, Poland
Specjalistyczny Gabinet Diabetologiczny Radoslaw RumianowskiGorzów Wielkopolski, Poland
SP ZOZ w Kalwarii ZebrzydowskiejKalwaria Zebrzydowska, Poland
Linden sp. z o.o. sp. k.Krakow, Poland
Diamond Clinic sp zooKrakow, Poland
Beata Miklaszewicz & Dariusz Dabrowski "CARDIAMED" s.j.Legnica, Poland
Serce Sp. z o.o.Leszno, Poland
Gabinet Lekarski Malgorzata Saryusz-WolskaLodz, Poland
Centrum Terapii Wspolczesnej - J.M. Jasnorzewska S.K.A.Lodz, Poland
Niepubliczny Zaklad Opieki Zdrowotnej Przychodnia Specjalistyczna A Wittek H Rudzki Sp. j.Ruda Śląska, Poland
Lukmed 2 Sp. z o.o.Siedlce, Poland
Szpital Czerniakowski Sp. z o.o.Warsaw, Poland
Samodzielny Publiczny Szpital Kliniczny Nr 1 im. Prof. SzyszkoZabrze, Poland
Prywatna Praktyka Lekarska Anna ChudobaŻyrardów, Poland
Hospital de CascaisAlcabideche, Portugal
ULS Almada-Seixal E.P.E. - Hospital Garcia de OrtaAlmada, Portugal
ULS De Braga, E.P.E. - Hospital de BragaBraga, Portugal
APDP - Associação Protectora dos Diabéticos de PortugalLisbon, Portugal
Hosp. das Forças Armadas_ EndocrinologiaLisbon, Portugal
ULS De São João, E.P.E. - Hospital de São JoãoPorto, Portugal
ULS De Matosinhos E.P.E.- Hospital Pedro HispanoSenhora Da Hora, Matosinhos, Portugal
Hospital da Luz Arrabida, S.A.Vila Nova de Gaia, Portugal
Institutul National De Diabet Nutritie Si Boli Metabolice Prof.Dr.N.Paulescu Bucuresti- Ion MovilaBucharest, Bucharest, Romania
Poli Cardinal Med SrlReghin, Mureș County, Romania
CMI Dr. Pletea Noemi SRLBacau, Romania
SC Nutrilife SRLBucharest, Romania
Diabet Med SRLBucharest, Romania
Medical Practice SRLOradea, Romania
Spital Judetean De Urgenta Satu MareSatu Mare, Romania
Cabinet Medical Dr Geru SRLTimișoara, Romania
King Chulalongkorn Memorial Hospital_EndocrinologyBangkok, Thailand
Rajavithi Hospital_Diabetes and EndocrinologyBangkok, Thailand
Ramathibodi HospitalBangkok, Thailand
Siriraj HospitalBangkok, Thailand
Srinagarind HospitalKhon Kaen, Thailand
Başkent Üniversitesi Adana-EndokrinolojiAdana /yüreği̇r, Turkey (Türkiye)
Ankara Bilkent Şehir Hastanesi-DahiliyeAnkara, Turkey (Türkiye)
İnönü Üniversitesi Turgut Özal Tıp Merkezi Hastanesi- EndokrinolojiBattalgazi / Malatya, Turkey (Türkiye)
Göztepe Prof. Dr.Süleyman Yalçın Şehir Hastanesi- DahiliyeIstanbul, Turkey (Türkiye)
Marmara Üniversitesi Pendik EAH- EndokrinolojiPendik/istanbul, Turkey (Türkiye)
Sivas Cumhuriyet Üniversitesi Hastanesi -EndokrinolojiSivas, Turkey (Türkiye)
Adana Şehir Eğitim ve Araştırma Hastanesi-EndokrinolojiYüreğir/Adana, Turkey (Türkiye)