RecruitingPhase 3

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

NCT06976216

What is this trial?

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Am I eligible?

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What's involved?

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Where and how to apply

Primary location

Healthy Brain Clinic

Long Beach, California, United States

+115 additional locations

Contact

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

855-907-3286 Clinical.Trials@bms.com

View on ClinicalTrials.gov

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Quick facts

Start date: 2025-07-14
Enrollment: 586 participants
Sponsor: Bristol-Myers Squibb
Purpose: treatment

Locations (116)

Healthy Brain ClinicLong Beach, California, United States
Anderson Clinical ResearchRedlands, California, United States
Mountain Neurological Research CenterBasalt, Colorado, United States
Georgetown University Medical CenterWashington D.C., District of Columbia, United States
JEM Research InstituteAtlantis, Florida, United States
VIN-Julie SchwartzbardAventura, Florida, United States
Merritt Island Medical Research, LLCMerritt Island, Florida, United States
Renstar Medical ResearchOcala, Florida, United States
Alzheimer's Research and Treatment CenterStuart, Florida, United States
Charter Research - Lady LakeThe Villages, Florida, United States
Local Institution - 0016Columbus, Georgia, United States
Center for Advanced Research & EducationGainesville, Georgia, United States
Re:Cognition Health - ChicagoChicago, Illinois, United States
Ascension Alexian BrothersElk Grove Village, Illinois, United States
Boston Center for MemoryNewton, Massachusetts, United States
HealthPartners Neuroscience CenterSaint Paul, Minnesota, United States
Advanced Memory Research Institute of New JerseyToms River, New Jersey, United States
NYU Langone HealthNew York, New York, United States
Local Institution - 0259New York, New York, United States
SUNY Upstate Medical UniversitySyracuse, New York, United States
AMC Research, LLCMatthews, North Carolina, United States
Ohio State UniversityColumbus, Ohio, United States
NDx Clinical Research Inc.Dayton, Ohio, United States
Summit HeadlandsPortland, Oregon, United States
Local Institution - 0004Abington, Pennsylvania, United States
Rhode Island Mood & Memory Research InstituteEast Providence, Rhode Island, United States
Neurology Clinic, P.C.Cordova, Tennessee, United States
Gadolin ResearchBeaumont, Texas, United States
Fundación para el Estudio y Tratamiento de Enfermedades Mentales (FETEM)Buenos Aires, Buenos Aires F.D., Argentina
Local Institution - 0271Buenos Aires, Argentina
Fundación Lennox - Instituto Modelo de NeurologíaCórdoba, Argentina
Sanatorio Morra S.A.Córdoba, Argentina
Instituto KremerCórdoba, Argentina
Southern NeurologyKogarah, New South Wales, Australia
KARA Institute for Neurological DiseasesMacquarie Park, New South Wales, Australia
NeuroCentrixCarlton, Victoria, Australia
Neurodegenerative Disorders ResearchPerth, Western Australia, Australia
St Vincent's Hospital Sydney LimitedDarlinghurst, Australia
Local Institution - 0168Brasília, Federal District, Brazil
Instituto de Neurologia de CuritibaCuritiba, Paraná, Brazil
Local Institution - 0266Aracaju, Sergipe, Brazil
Hospital das Clinicas FMUSPSão Paulo, Brazil
OCT Research ULCKelowna, British Columbia, Canada
Richmond Clinical TrialsRichmond, British Columbia, Canada
Centricity Research Halifax MultispecialtyHalifax, Nova Scotia, Canada
Ottawa Memory ClinicOttawa, Ontario, Canada
Toronto Memory ProgramToronto, Ontario, Canada
MoCA Research and Innovation Inc.Greenfield Park, Quebec, Canada
Diex Recherche VictoriavilleVictoriaville, Quebec, Canada
ALPHA Recherche CliniqueQuébec, Canada
Local Institution - 0094Santiago, Santiago Metropolitan, Chile
Local Institution - 0089Santiago, Santiago Metropolitan, Chile
Local Institution - 0241Santiago, Santiago Metropolitan, Chile
Local Institution - 0230Antofagasta, Chile
Local Institution - 0215Zagreb, City of Zagreb, Croatia
Poliklinika NeuronZagreb, City of Zagreb, Croatia
Klinika za psihijatriju "Vrapče"Zagreb, Croatia
Neuro Health CentrumBrno, Brno-město, Czechia
AGE CentrumOlomouc, Olomouc Region, Czechia
A-ShinePilsen, Plzeň-město, Czechia
Local Institution - 0224Prague, Praha 6, Czechia
NeuropsychiatriePrague, Praha 6, Czechia
Local Institution - 0222Prague, Praha 8, Czechia
Vestra ClinicsRychnov nad Kněžnou, Czechia
Local Institution - 0295Nice, Alpes-Maritimes, France
Local Institution - 0289Toulouse, Haute-Garonne, France
Local Institution - 0290Rouen, Haute-Normandie, France
Local Institution - 0291Montpellier, Languedoc-Roussillon, France
Local Institution - 0299Reims, Marne, France
Local Institution - 0293Villeurbanne, Rhône, France
Local Institution - 0294Dijon, France
Universitätsklinikum Münster - Albert Schweitzer CampusMünster, North Rhine-Westphalia, Germany
Universitätsmedizin Johannes Gutenberg Universität MainzMainz, Rhineland-Palatinate, Germany
Charite-Universitaetsmedizin Berlin - Campus Benjamin Franklin (CBF)Berlin, State of Berlin, Germany
Local Institution - 0277Bremen, Germany
Local Institution - 0275Hamburg, Germany
TUM KlinikumMunich, Germany
University General Hospital of AlexandroupoliAlexandroupoli, Anatolikí Makedonía Kai Thráki, Greece
Local Institution - 0256Athens, Attikí, Greece
Aiginiteio University HospitalAthens, Attikí, Greece
University General Hospital of LarissaLarissa, Thessalía, Greece
Local Institution - 0288Bengaluru, Karnataka, India
Local Institution - 0282Hyderabad, Telangana, India
Local Institution - 0285Hyderabad, Telangana, India
Local Institution - 0287Varanasi, Uttar Pradesh, India
Local Institution - 0286Kolkata, West Bengal, India
Fondazione IRCCS Cà Granda Ospedale Maggiore PoliclinicoMilan, Lombardy, Italy
Ospedale San RaffaeleMilan, Lombardy, Italy
Fondazione IRCCS San Gerardo dei TintoriMonza, Lombardy, Italy
Azienda Ospedaliera Spedali Civili di BresciaBrescia, Italy
Local Institution - 0296's-Hertogenbosch, North Brabant, Netherlands
Local Institution - 0297Amsterdam, North Holland, Netherlands
Local Institution - 0298Zwolle, Overijssel, Netherlands
Centrum Medyczne HCPPoznan, Greater Poland Voivodeship, Poland
Osrodek Badan Klinicznych CLINSANTE S.C.Torun, Kuyavian-Pomeranian Voivodeship, Poland
MlynowaMed PsychiatricBialystok, Podlaskie Voivodeship, Poland
Centrum Badan Klinicznych PI-House sp. z o.o.Gdansk, Pomeranian Voivodeship, Poland
Instituto De Neurologia Dra. Ivonne FragaSan Juan, Puerto Rico
Prof. Dr. Alexandru Obregia Psychiatry HospitalBucharest, Bucharest, Romania
Prof. Dr. Alexandru Obregia Psychiatry HospitalBucharest, Bucharest, Romania
Institutul Național de Gerontologie și Geriatrie "Ana Aslan"Bucharest, Romania
Centrul de Sanatate MintalaBucharest, Romania
Institutul de Psihiatrie SocolaIași, Romania
Chonnam National University HospitalGwangju, Kwangju-Kwangyǒkshi, South Korea
Seoul National University Bundang HospitalSeongnam, Kyǒnggi-do, South Korea
Seoul National University HospitalSeoul, Seoul-teukbyeolsi [Seoul], South Korea
Hanyang University Seoul HospitalSeoul, Seoul-teukbyeolsi [Seoul], South Korea
Konkuk University Medical CenterSeoul, Seoul-teukbyeolsi [Seoul], South Korea
Samsung Medical CenterSeoul, Seoul-teukbyeolsi [Seoul], South Korea
Ewha Womans University Seoul HospitalSeoul, Seoul-teukbyeolsi [Seoul], South Korea
Hospital Victoria EugeniaSeville, Andalusia, Spain
Hospital Universitari General de CatalunyaSant Cugat del Vallès, Barcelona [Barcelona], Spain
Hospital Clínic de BarcelonaBarcelona, Catalunya [Cataluña], Spain
Hospital Universitari de Santa MariaLleida, Lleida [Lérida], Spain
Clinica Universidad de NavarraPamplona, Navarre, Spain
Hospital Clinico San CarlosMadrid, Spain