Active, not recruitingPhase 3

Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD)

NCT05531526

What is this trial?

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Where and how to apply

Primary location

IMA Clinical Research Phoenix

Phoenix, Arizona, United States

+197 additional locations

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Quick facts

Start date: 2022-12-23
Enrollment: 1,535 participants
Sponsor: AriBio Co., Ltd.
Purpose: treatment

Locations (198)

IMA Clinical Research PhoenixPhoenix, Arizona, United States
Perseverance Research Center, LLCScottsdale, Arizona, United States
Clinical Endpoints - N. ScottsdaleScottsdale, Arizona, United States
Banner Sun Health Research InstituteSun City, Arizona, United States
Voyage MedicalTempe, Arizona, United States
Sutter Health's Palo Alto Medical FoundationBurlingame, California, United States
Neuro-Pain Medical CenterFresno, California, United States
Fullerton Neurology and Headache CenterFullerton, California, United States
Esperanza ClinicalMurrieta, California, United States
Valley Clinical Trials, INCNorthridge, California, United States
Havana Research InstitutePasadena, California, United States
Kaizen Brain CenterSan Diego, California, United States
Adaptive ResearchSan Jose, California, United States
The Neuron ClinicSan Marcos, California, United States
Stanford Neuroscience Health CenterStanford, California, United States
Denver Neurological ResearchDenver, Colorado, United States
Mile High Research CenterDenver, Colorado, United States
CenExel Rocky Mountain Clinical ResearchEnglewood, Colorado, United States
Topaz Clinical ResearchApopka, Florida, United States
BayCare Health System, IncClearwater, Florida, United States
Vertex Research GroupClermont, Florida, United States
Arrow Clinical TrialDaytona Beach, Florida, United States
Brainstorm Research - LoxahatcheeLoxahatchee Groves, Florida, United States
ClinCloud LLCMaitland, Florida, United States
Verus Clinical Research, CorpMiami, Florida, United States
Vitae Research Center, LLCMiami, Florida, United States
Caro Medcenter and Community ResearchMiami, Florida, United States
Allied Biomedical Research Institute, IncMiami, Florida, United States
Future Life Clinical TrialsMiami, Florida, United States
Brainstorm ResearchMiami, Florida, United States
Meridian International Research, IncMiami Gardens, Florida, United States
Charter Research - OrlandoOrlando, Florida, United States
K2 Medical ResearchOrlando, Florida, United States
JEM Research InstitutePalm Beach, Florida, United States
Progressive Medical ResearchPort Orange, Florida, United States
Angels Clinical Research Institute, Inc. - TampaTampa, Florida, United States
Charter Research - The VillagesThe Villages, Florida, United States
ClinCloud, LLC MelbournViera, Florida, United States
Conquest ResearchWinter Park, Florida, United States
iResearch -AtlantaAtlanta, Georgia, United States
Atlanta Neuroscience InstituteAtlanta, Georgia, United States
Accel Research SitesDecatur, Georgia, United States
iResearchSavannah, Georgia, United States
Re:Cognition Health - ChicagoChicago, Illinois, United States
Tandem Clinical ResearchNew Orleans, Louisiana, United States
BTC of New BedfordNew Bedford, Massachusetts, United States
Boston Center for MemoryNewton, Massachusetts, United States
Headlands Research - Eastern MAPlymouth, Massachusetts, United States
Boston PaincareWaltham, Massachusetts, United States
Sharlin Health Neuroscience Research CenterOzark, Missouri, United States
AlivationLincoln, Nebraska, United States
Wake Research- Clinical Research Center of Nevada, LLCLas Vegas, Nevada, United States
Advanced Memory Research Institute of New JerseyToms River, New Jersey, United States
Dent Neuroscience Research CenterAmherst, New York, United States
Mid-Hudson Medical Research, PLLC - New WindsorNew Windsor, New York, United States
Triad Clinical TrialsGreensboro, North Carolina, United States
AMC Research, LLCMatthews, North Carolina, United States
Accellacare of Winston-Salem, Triad Neurological AssociatesWinston-Salem, North Carolina, United States
NeuroScience Research Center, LLCCanton, Ohio, United States
American Clinical Research Institute, LLCDayton, Ohio, United States
Rhode Island Mood and Memory REsearchEast Providence, Rhode Island, United States
Health ConceptsRapid City, South Dakota, United States
Neurology Clinic, P.C.Cordova, Tennessee, United States
Center for Biomedical Research, LLC - Genesis Neuroscience ClinicKnoxville, Tennessee, United States
Gadolin Research LLCBeaumont, Texas, United States
Kerwin Medical CenterDallas, Texas, United States
Cognition Health Corporation- TexasHouston, Texas, United States
Clinical Trial Network - HoustonHouston, Texas, United States
Bhupesh Dihenia, MD, PALubbock, Texas, United States
Wasatch Clinical Research, LLCSalt Lake City, Utah, United States
Cognition Health CorporationFairfax, Virginia, United States
Integrated Neurology ServicesFalls Church, Virginia, United States
Kingfisher CooperativeSpokane, Washington, United States
Vaught Neurological Services, PLLCCrab Orchard, West Virginia, United States
Medical College of WisconsinWauwatosa, Wisconsin, United States
Centricity Research - HalifaxHalifax, Canada
Okanagan Clinical TrialsKelowna, Canada
Parkwood InstituteLondon, Canada
Baycrest Academy for Research and EducationNorth York, Canada
Kawartha Centre - Redefining Healthy AgingPeterborough, Canada
Centricity ResearchToronto, Canada
Sunnybrook Health Sciences CentreToronto, Canada
University Health Network-Toronto Western HospitalToronto, Canada
Royal Jubilee HospitalVictoria, Canada
Medical Arts Health Research Group - West VancouverWest Vancouver, Canada
Beijing Anding Hospital Capital Medical UniversityBeijing, China
Beijing Friendship Hospital,Capital Medical UniversityBeijing, China
Beijing Tiantan Hospital, Capital Medical UniversityBeijing, China
Peking Union Medical College HospitalBeijing, China
Peking University Sixth HospitalBeijing, China
Xuanwu Hospital Capital Medical UniversityBeijing, China
The First Hospital of Jilin UniversityChangchun, China
Xiangya Hospital of Central South UniversityChangsha, China
The First Affiliated Hospital of Chongqing Medical UniversityChongqing, China
Guangdong Provincial People's HospitalGuangzhou, China
The Affiliated Brain Hospital Of Guangzhou Medical UniversityGuangzhou, China
The First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, China
Anhui Provincial HospitalHefei, China
Tianjin Medical University General HospitalHeping, China
The Second Affiliated Hospital of Nanchang UniversityNanchang, China
Nanjing Drum Tower HospitalNanjing, China
The Second Affiliated Hospital of Nanjing Medical UniversityNanjing, China
Huashan Hospital affiliated to Fudan UniversityShanghai, China
Renji Hospital, Shanghai Jiao Tong University School of MedicineShanghai, China
The First Hospital of Hebei Medical UniversityShijiazhuang, China
The First Affiliated Hospital of Soochow UniversitySuzhou, China
The Second Affiliated Hospital of Soochow UniversitySuzhou, China
Tongji Hospital Of Tongji UniversityWuhan, China
Xuzhou Central HospitalXuzhou, China
Fakultni nemocnice u sv. Anny v BrneBrno, Czechia
NeuroHK s.r.o.Choceň, Czechia
Fakultni nemocnice Hradec KraloveHradec Králové, Czechia
Ambulance Smrkova ulice (A-Shine s.r.o.)Pilsen, Czechia
FORBELI s.r.oPrague, Czechia
INEP Medical s.r.o.Prague, Czechia
Neuropsychiatrie s.r.o.Prague, Czechia
Vestra ClinicsRychnov nad Kněžnou, Czechia
Sanos Clinic - GandrupGandrup, Denmark
Sanos Clinic - HerlevHerlev, Denmark
Sanos Clinic Syddanmark - VejleVejle, Denmark
CHU de Lille - Hopital Roger SalengroLille, France
AP-HM - Hopital de la TimoneMarseille, France
CHU de Nantes - Hopital Nord LaennecNantes, France
AP-HP Hopital BrocaParis, France
AP-HP Hopital LariboisiereParis, France
AP-HP Hopital Pitie-SalpetriereParis, France
CHU Rennes - Hopital PontchaillouRennes, France
CHRU de Strasbourg - Hopital de HautepierreStrasbourg, France
CHU de Toulouse - Hopital La GraveToulouse, France
HCL - Hopital des CharpennesVilleurbanne, France
Universitaetsklinikum Aachen, AoeRAachen, Germany
Zentrum fuer klinische Forschung Dr. med. I. SchoellBad Homburg, Germany
Charite Universitaetsmedizin BerlinBerlin, Germany
Bezirkskrankenhaus GuenzburgGünzburg, Germany
Universitaetsklinikum des SaarlandesHomburg, Germany
Institut fuer Studien zur Psychischen Gesundheit (ISPG)Mannheim, Germany
Azienda Ospedaliero-Universitaria delle MarcheAncona, Italy
IRCCS Istituto Centro San Giovanni di Dio FatebenefratelliBrescia, Italy
ASST Grande Ospedale Metropolitano NiguardaMilan, Italy
IRCCS Ospedale San RaffaeleMilan, Italy
Fondazione IRCCS San Gerardo dei TintoriMonza, Italy
Azienda Ospedaliero Universitaria PisanaPisa, Italy
Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro CuoreRoma, Italy
Azienda Ospedaliero Universitaria Policlinico Umberto IRoma, Italy
AOU Citta della Salute e della Scienza di Torino - Ospedale le MolinetteTorino, Italy
Pia Fondazione di Culto e Religione Cardinale Giovanni PanicoTricase, Italy
Brain Research Center Den Bosch's-Hertogenbosch, Netherlands
Brain Research CenterAmsterdam, Netherlands
Amphia Ziekenhuis - Locatie Breda MolengrachtBreda, Netherlands
Brain Research Center ZwolleZwolle, Netherlands
KLIMED Marek KlimkiewiczBialystok, Poland
Podlaskie Centrum PsychogeriatriiBialystok, Poland
NEURO-CARE Sp. z o.o. Sp. KomandytowaKatowice, Poland
Osrodek Alzheimerowski Sp. z o.oŚcinawa, Poland
ETG Neurosciences Sp. Z.o.o.Warsaw, Poland
NZOZ Wroclawskie Centrum AlzheimerowskiWroclaw, Poland
Seoul National University Bundang HospitalSeongnam-si, Bundang-gu, South Korea
Chonnam National University HospitalGwangju, Dong-Gu, South Korea
Ewha Womans University Seoul HospitalSeoul, Gangseo-gu, South Korea
Hallym University Chuncheon Sacred Heart HospitalChuncheon, Gangwon-do, South Korea
Gachon University Gil Medical CenterIncheon, Namdong-Gu, South Korea
Severance Hospital, Yonsei University Health SystemSeoul, Seodaemun-gu, South Korea
Ewha Womans University Mokdong HospitalSeoul, Seoul, South Korea
Soonchunhyang University Hospital CheonanCheonan, South Korea
Kyungpook National University Chilgok HospitalDaegu, South Korea
Yeungnam University HospitalDaegu, South Korea
Hanyang University Guri HospitalGuri-si, South Korea
Uijeongbu St. Mary's HospitalGyeonggi-do, South Korea
Inha University HospitalIncheon, South Korea
Catholic Kwandong University International St.Mary's HospitalIncheon, South Korea
Asan Medical CenterSeoul, South Korea
The Catholic University of Korea Seoul St.Mary's HospitalSeoul, South Korea
Chung ang University HospitalSeoul, South Korea
Korea University Guro HospitalSeoul, South Korea
Eunpyeong St.Mary's HospitalSeoul, South Korea
Gangnam Severance Hospital, Yonsei University Health SystemSeoul, South Korea
Konkuk University HospitalSeoul, South Korea
Samsung Medical CenterSeoul, South Korea
Severance Hospital, Yonsei University Health SystemSeoul, South Korea
Ajou University HospitalSuwon, South Korea
Fundacio ACE - Institut Catala de Neurociencies Aplicades (Alzheimer Research Center Memory Clinic)Barcelona, Spain
Hospital del MarBarcelona, Spain
Hospital Universitario Vall d'HebronBarcelona, Spain
Hospital Universitario Juan Ramon JimenezHuelva, Spain
Hospital Universitario 12 de OctubreMadrid, Spain
Hospital Universitario Ramon y CajalMadrid, Spain
Clinica Universidad de Navarra - PamplonaPamplona, Spain
Hospital Clinico Universitario de SalamancaSalamanca, Spain
Policlinica GipuzkoaSan Sebastián, Spain
Hospital Universitario Virgen del RocioSeville, Spain
Hospital Universitari i Politecnic La FeValencia, Spain
Fulbourn HospitalCambridge, United Kingdom
Cornwall Partnership NHS Foundation TrustCornwell, United Kingdom
Royal Devon University Healthcare NHS Foundation TrustExeter, United Kingdom
Hammersmith HospitalLondon, United Kingdom
NeuroClin GlasgowMotherwell, United Kingdom
Warneford HospitalOxford, United Kingdom
Southern Health NHS Foundation TrustSouthampton, United Kingdom