TerminatedPhase 2

A Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Disease

NCT03289143

What is this trial?

Generating plain-language summary...

Am I eligible?

Generating eligibility summary...

What's involved?

Summarizing study design...

Where and how to apply

Primary location

University of Alabama at Birmingham

Birmingham, Alabama, United States

+132 additional locations

View on ClinicalTrials.gov

Save this trial

Quick facts

Start date: 2017-10-04
Enrollment: 457 participants
Sponsor: Genentech, Inc.
Purpose: treatment

Locations (133)

University of Alabama at BirminghamBirmingham, Alabama, United States
California Clinical TrialsGlendale, California, United States
University of California IrvineIrvine, California, United States
Pharmacology Research InstNewport Beach, California, United States
Stanford Neuroscience Health Center (SNHC)Palo Alto, California, United States
Pacific Research Network - PRNSan Diego, California, United States
Neurological Research InstSanta Monica, California, United States
Collaborative Neuroscience Network Inc.Torrance, California, United States
Invicro, a Konica Minolta companyNew Haven, Connecticut, United States
Yale UniversityNew Haven, Connecticut, United States
KI Health Partners, LLC; New England Institute for Clinical ResearchStamford, Connecticut, United States
Georgetown University HospitalWashington D.C., District of Columbia, United States
JEM Research LLCAtlantis, Florida, United States
Bradenton Research CenterBradenton, Florida, United States
Brain Matters Research, Inc.Delray Beach, Florida, United States
Neuropsychiatric Research; Center of Southwest FloridaFort Myers, Florida, United States
Miami Jewish Health SystemsMiami, Florida, United States
Collier Neurologic SpecialistsNaples, Florida, United States
Compass Research East, LLCOrlando, Florida, United States
Stedman Clinical Trials, LLCTampa, Florida, United States
Alzheimer's Research and Treatment CenterWellington, Florida, United States
Premiere Research InstituteWest Palm Beach, Florida, United States
Emory University; Global HealthAtlanta, Georgia, United States
Rush Alzheimer's Disease Cntr.Chicago, Illinois, United States
Alexian Brothers Neuroscience InstituteElk Grove Village, Illinois, United States
Southern Illinois University, School of MedicineSpringfield, Illinois, United States
Eastern Maine Medical CenterBangor, Maine, United States
Brigham & Women's Hosp; TIMI Study GrpBoston, Massachusetts, United States
Alzheimers Disease CenterQuincy, Massachusetts, United States
Health Partners Institute for Education and ResearchSaint Paul, Minnesota, United States
NeuroCognitive InstituteMount Arlington, New Jersey, United States
Advanced Memory Research Institute of NJToms River, New Jersey, United States
Albany Medical College; NeurologyAlbany, New York, United States
Empire Neurology PC; MS Center of Northeastern NYLatham, New York, United States
Columbia Univ Medical CenterNew York, New York, United States
University of Rochester; AD-CARERochester, New York, United States
Summit Research Network Inc.Portland, Oregon, United States
Abington Neurological AssociatesAbington, Pennsylvania, United States
Rhode Island Mood & Memory Research InstituteEast Providence, Rhode Island, United States
Butler HospitalProvidence, Rhode Island, United States
Neurology Clinic PCCordova, Tennessee, United States
New Orleans Center For Clinical ResearchKnoxville, Tennessee, United States
Clinical Neuroscience Research Associates, Inc.Bennington, Vermont, United States
St Vincents Medical CentreDarlinghurst, New South Wales, Australia
Southern NeurologyKogarah, New South Wales, Australia
Queensland University of TechnologyMermaid Waters, Queensland, Australia
Eastern Clinical Research Unit; PharmacyBox Hill, Victoria, Australia
HammondCare Aged Psychiatry Clinical TrialsMalvern, Victoria, Australia
The Alfred Hospital, Melbourne; Thrombosis and Haemostasis UnitMelbourne, Victoria, Australia
Neuro Trials VictoriaNoble Park, Victoria, Australia
Royal Melbourne HospitalParkville, Victoria, Australia
UZ BrusselBrussels, Belgium
AZ GroeningeKortrijk, Belgium
UZ LeuvenLeuven, Belgium
AZ Delta Campus WestlaanRoeselare, Belgium
JBN Medical Diagnostic Services; Clinical Trials DivisionBurlington, Ontario, Canada
Parkwood Institute, Mental Health Care BuildingLondon, Ontario, Canada
Elisabeth Bruyere HospitalOttawa, Ontario, Canada
Toronto Memory ProgramToronto, Ontario, Canada
Centre for Memory and AgingToronto, Ontario, Canada
Toronto Sunnybrook HospitalToronto, Ontario, Canada
Toronto Western HospitalToronto, Ontario, Canada
Recherches Neuro-HippocameGatineau, Quebec, Canada
Center For Clinical and Basic Research (Ccbr); Site Management OrganisationAalborg, Denmark
CCBR - Vejle - DKVejle, Denmark
Groupe Hospitalier Pellegrin; Service de Neurologie - 3ème étageBordeaux, France
Hopital Neurologique Pierre WertheimerBron, France
Hopital Roger SalengroLille, France
CHU de la Timone - Hopital d Adultes; Service de NeurologieMarseille, France
Hopital Gui de Chauliac; NeurologieMontpellier, France
Hopital Fernand Widal CentreParis, France
Groupe Hospitalier Pitie-SalpetriereParis, France
CHU RennesRennes, France
CHU Hautepierre; ACTR Association Recherche Clinique RhumatologieStrasbourg, France
CHU Strasbourg - Hôpital HautepierreStrasbourg, France
Hopital de La GraveToulouse, France
Hopital des CharpennesVilleurbanne, France
Klinikum Bayreuth; Krankenhaus Hohe WarteBayreuth, Germany
Praxis Dr. med. Volker ShumannBerlin, Germany
Studienambulanz emovis GmbH; St. Joseph KrankenhausBerlin, Germany
Charite Campus Benjamin FranklinBerlin, Germany
Neurologisch-psychiatrische Praxis am BroseparkBerlin, Germany
Bezirkskrankenhaus GünzburgGünzburg, Germany
Klinische Forschung Hannover-Mitte GmbHHanover, Germany
Klinikum rechts der Isar der TU München; Klinik & Poliklinik für NeurologieMünchen, Germany
ZNS Siegen im MVZ WeidenauSiegen, Germany
Universitätsklinik Tübingen; Psychiatrie und PsychotherapieTübingen, Germany
Universitätsklinikum Ulm; Klinik für NeurologieUlm, Germany
Az. Osp. C. Panico; Rep. Ematologia E TrapiantoTricase - LE, Apulia, Italy
Umberto I Policlinico di Roma-Università di Roma La SapienzaRome, Lazio, Italy
Ospedale San Giovanni Calibita Fatebenefratell;NeurologiaRome, Lazio, Italy
Azienda Ospedaliero Universitaria San Martino; Dip. di Neuroscienze Oftalmologia e GeneticaGenoa, Liguria, Italy
IRCCS Centro San Giovanni di Dio FBFBrescia, Lombardy, Italy
Fondazione IRCCS Istituto Neurologico Carlo BestaMilan, Lombardy, Italy
IRCCS Neuromed; Neurologia I-Centro studio e cura delle demenze e UVAPozzilli, Molise, Italy
Jeroen Bosch Ziekenhuis's-Hertogenbosch, Netherlands
Brain Research Center B.VAmsterdam, Netherlands
Podlaskie Centrum PsychogeriatriiBialystok, Poland
PALLMED Sp. z o.o. prowadząca NZOZ DOM SUE RYDERBydgoszcz, Poland
M.A. - LEK A.M.Maciejowscy SC.Katowice, Poland
Novo-Med Zielinski i wspolnicy Sp. j.Katowice, Poland
Malopolskie Centrum MedyczneKrakow, Poland
NEURO - KARD Ośrodek Badań KlinicznychPoznan, Poland
NEURO-CARE Sp. z o.o. Sp. KomandytowaSiemianowice Śląskie, Poland
Senior Sp. Z O.O. Poradnia PsychogeriatrycznaSopot, Poland
EroMedisSzczecin, Poland
AMED Medical CenterWarsaw, Poland
Centrum Medyczne NeuroProtectWarsaw, Poland
NZOZ WCAWroclaw, Poland
Hospital Mutua de TerrassaTerrassa, Barcelona, Spain
Policlinica GuipuzcoaDonostia / San Sebastian, Guipuzcoa, Spain
Clinica Universitaria de Navarra; Servicio de NeurologíaPamplona, Navarre, Spain
Hospital Virgen del PuertoPlasencia, Palencia, Spain
Hospital de Cruces; Servicio de NeurologiaBarakaldo, Vizcaya, Spain
Hospital Perpetuo Socorro, Servicio de GeriatriaAlbacete, Spain
Hospital de la Santa Creu i Sant PauBarcelona, Spain
Fundación ACE; Servicio de NeurologíaBarcelona, Spain
Hospital Clinic i Provincial de BarcelonaBarcelona, Spain
Hospital Universitario Reina Sofia; Servicio de NeurologiaCórdoba, Spain
Hospital Universitario Ramon y CajalMadrid, Spain
Hospital de Cantoblanco; Servicio de GeriatriaMadrid, Spain
Hospital Universitario Virgen MacarenaSeville, Spain
Hospital Universitario Dr. Peset; Servicio de NeurologiaValencia, Spain
Hospital Universitari i Politecnic La Fe de ValenciaValencia, Spain
Länssjukhuset RyhovJönköping, Sweden
Länssjukhuset Kalmar; OncologyKalmar, Sweden
Skane University Hospital Malmo/Lund, Dept.of Hematology and Coagulation DisordersMalmö, Sweden
Sahlgrenska Univ Hospital Mölndal; Department of NephrologyMölndal, Sweden
Karolinska Universitetssjukhuset HuddingeStockholm, Sweden
Glasgow Memory ClinicGlasgow, United Kingdom
RE:Cognition HealthLondon, United Kingdom
The National Hospital for Neurology & NeurosurgeryLondon, United Kingdom
Re:Cognition Health GuildfordSurrey, United Kingdom