TerminatedPhase 3

A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD).

NCT02670083

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Where and how to apply

Primary location

Banner Alzheimer's Institute

Phoenix, Arizona, United States

+195 additional locations

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Quick facts

Start date: 2016-03-22
Enrollment: 813 participants
Sponsor: Hoffmann-La Roche
Purpose: treatment

Locations (196)

Banner Alzheimer's InstitutePhoenix, Arizona, United States
Pharmacology Research InstEncino, California, United States
Collaborative Neuroscience Network Inc.Long Beach, California, United States
Alliance for Wellness, dba Alliance for ResearchLong Beach, California, United States
Pharmacology Research InstituteLos Alamitos, California, United States
USC Keck School Of MedicineLos Angeles, California, United States
UCLA Medical Center, Department of NeurologyLos Angeles, California, United States
Pharmacology Research InstNewport Beach, California, United States
Shankle ClinicNewport Beach, California, United States
Stanford Univ Medical CenterPalo Alto, California, United States
Anderson Clinical Research, Inc.Redlands, California, United States
University of California, Davis; Alzheimers Disease Center, Department of NeurologySacramento, California, United States
UCSF - Memory and Aging CenterSan Francisco, California, United States
Neurological Research InstSanta Monica, California, United States
North Bay Neuro Science InstituteSebastopol, California, United States
Associated Neurologists PC - DanburyDanbury, Connecticut, United States
Institute for Neurodegenerative DisordersNew Haven, Connecticut, United States
Yale University School Of MedicineNew Haven, Connecticut, United States
Research Center for Clinical Studies, Inc.Norwalk, Connecticut, United States
Bradenton Research CenterBradenton, Florida, United States
Quantum LaboratoriesDeerfield Beach, Florida, United States
Brain Matters Research, Inc.Delray Beach, Florida, United States
Galiz Research, LLCHialeah, Florida, United States
Jacksonville Center For Clinical ResearchJacksonville, Florida, United States
Alzheimer's Research and Treatment CenterLake Worth, Florida, United States
Merritt - Island Medical ResearchMerritt Island, Florida, United States
Miami Jewish Health SystemsMiami, Florida, United States
Renstar Medical ResearchOcala, Florida, United States
Bioclinica ResearchOrlando, Florida, United States
Progressive Medical ResearchPort Orange, Florida, United States
Johnnie B. Byrd Sr. Alzheimer's Center & Research InstituteTampa, Florida, United States
Stedman Clinical Trials, LLCTampa, Florida, United States
Compass ResearchThe Villages, Florida, United States
Emory UniversityAtlanta, Georgia, United States
NeuroStudies.net, LLCDecatur, Georgia, United States
Alexian Brothers Neurosci InstElk Grove Village, Illinois, United States
Southern Illinois University, School of MedicineSpringfield, Illinois, United States
Indiana UniversityIndianapolis, Indiana, United States
MidAmerica Neuroscience InstitutePrairie Village, Kansas, United States
Maine Research AssociatesAuburn, Maine, United States
MMP NeurologyScarborough, Maine, United States
Springfield Neurology AssociatesSpringfield, Massachusetts, United States
Precise Research CentersFlowood, Mississippi, United States
The Cognitive and Research Center of New JerseySpringfield, New Jersey, United States
Advanced Memory Research Institute of NJToms River, New Jersey, United States
Albany Medical Faculty Physicians COmmunity Division. The Neurology GroupAlbany, New York, United States
Neurological Associates of Albany, PCAlbany, New York, United States
Dent Neurological InstituteAmherst, New York, United States
Columbia University Medical CenterNew York, New York, United States
South Shore Neurologic Associates P.C.Patchogue, New York, United States
Behavioral Health ResearchCharlotte, North Carolina, United States
Guilford Neurologic AssociatesGreensboro, North Carolina, United States
Valley Medical Primary CareCenterville, Ohio, United States
Insight Clinical Trials LLCShaker Heights, Ohio, United States
Oklahoma Clinical ResearchOklahoma City, Oklahoma, United States
Cutting Edge Research GroupOklahoma City, Oklahoma, United States
Central States ResearchTulsa, Oklahoma, United States
Summit Research Network Inc.Portland, Oregon, United States
Drexel Univ College of Med; Clinical Research GroupPhiladelphia, Pennsylvania, United States
Abington Neurological AssociatesWillow Grove, Pennsylvania, United States
Senior Adults Specialty ResearchAustin, Texas, United States
Kerwin Research Center, LLCDallas, Texas, United States
University of North Texas Health Science Center; Fort Worth Patient Care CenterFort Worth, Texas, United States
Sentara Medical GroupNorfolk, Virginia, United States
National Clinical Research Inc.-RichmondRichmond, Virginia, United States
Medical College of WisconsinMilwaukee, Wisconsin, United States
The Queen Elizabeth Hospital; NeurologyWoodville, South Australia, Australia
Caulfield Hospital; Aged Psychiatry Research UnitCaulfield, Victoria, Australia
Heidelberg Repatriation Hospital; Medical and Cognitive Research CentreHeidelberg West, Victoria, Australia
Neurodegenerative Disorders Research; NeurologyWest Perth, Western Australia, Australia
Konventhospital Barmherzige Brüder; Neurologie ILinz, Austria
UZ GentGhent, Belgium
ACIBADEM CITY CLINIC TOKUDA HOSPITAL EAD; Clinic of Neurology and Sleep MedicineSofia, Bulgaria
Alexandrovska hospital; Neurology DepartmentSofia, Bulgaria
Vancouver Hospital - UBC Hospital SiteVancouver, British Columbia, Canada
Vancouver Island Health AuthorityVictoria, British Columbia, Canada
Parkwood Hospital; Geriatric MedicineLondon, Ontario, Canada
Bruyere Continuing CareOttawa, Ontario, Canada
Kawartha Centre - Redefining Healthy AgingPeterborough, Ontario, Canada
The Centre for Memory and AgingToronto, Ontario, Canada
Toronto Western HospitalToronto, Ontario, Canada
Devonshire Clinical Research Inc.Woodstock, Ontario, Canada
CHA Hopital de I enfant-JesusQuébec, Quebec, Canada
Hospital Clínica BiblicaSan José, Costa Rica
ICIMED Instituto de Investigación en Ciencias MédicasSan José, Costa Rica
Clinical Hospital Centre Zagreb;Clinic for NeurologyZagreb, Croatia
Charles University, Medical faculty, Hradec Kralove ;Department of NeurologyHradec Králové, Czechia
General Teaching Hospital, Departmetn of NeurologyPrague, Czechia
Aarhus Universitetshospital, Neurologisk Afdeling F, DemensklinikkenAarhus N, Denmark
Rigshospitalet, HukommelsesklinikkenKøbenhavn Ø, Denmark
Terveystalo TampereTampere, Finland
CRST OyTurku, Finland
Hopital Avicenne; NeurologieBobigny, France
Hopital neurologique Pierre Wertheimer - CHU Lyon; NeurologieBron, France
Hopital Gui de Chauliac; NeurologieMontpellier, France
Hopital LariboisiereParis, France
CHU Poitiers - Hopital La MiletriePoitiers, France
Hopital Hautepierre; Centre dInvestigation CliniqueStrasbourg, France
CHU Toulouse - La GraveToulouse, France
Neurologische Praxis Dr. Andrej PaulsMünchen, Germany
Klinikum rechts der Isar der TU München; Klinik für Psychiatrie und PsychotherapieMünchen, Germany
Universitätsklinikum Münster; Klinik und Poliklinik für NeurologieMünster, Germany
Steinwachs Klaus; Arztpraxis fur Neurologie u. PsychiatrieNuremberg, Germany
Universitätsklinikum Rostock Zentrum für NervenheilkundeRostock, Germany
Universitätsklinikum Ulm; Klinik für NeurologieUlm, Germany
Studienzentrum Nordwest, Dr. med. Joachim Springub / Herr Wolfgang SchwarzWesterstede, Germany
Forschungszentrum RuhrWitten, Germany
Prince of Wales Hospital; Dept. of Medicine & TherapeuticsHong Kong, Hong Kong
Queen Mary Hospital, Division of Geriatric MedicineHong Kong, Hong Kong
Semmelweis University; Department of NeurologyBudapest, Hungary
Szabolcs-Szatmár-Bereg Megyei Kórházak - Jósa András Oktatókórház; PszichiátriaNyíregyháza, Hungary
University of Szeged; Department of PsychiatrySzeged, Hungary
Szent Borbala Korhaz; Neurologiai es Stroke OsztalyTatabánya, Hungary
Jávorszky Ödön Kórház, Neurológia és stroke osztályVác, Hungary
Fondazione Santa Lucia IRCCS; Neurologia e Riabilitazione NeurologicaRome, Lazio, Italy
Ospedale San Giovanni Calibita Fatebenefratell;NeurologiaRome, Lazio, Italy
Ente Ospedaliero Ospedali Galliera; Ambulatorio di NeurologiaGenoa, Liguria, Italy
Casa di Cura Policlinico; Dipartimento di Scienze NeuroriabilitativeMilan, Lombardy, Italy
Ospedale S. Maria Nascente; Fondazione Don Gnocchi; Dip. Neurologia RiabilitativaMilan, Lombardy, Italy
Ospedale Casati Passirana di Rho; Centro Regionale AlzheimerPassirana, Lombardy, Italy
Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia; S.C. GeriatriaPerugia, Umbria, Italy
Miyoshi Clinic of Neurology, HananosatoHiroshima, Japan
National Hospital Organization Hiroshima-Nishi Medical CenterHiroshima, Japan
Rakuwakai Otowarehabilitation HospitalKyoto, Japan
Mie University HospitalMie, Japan
National Hospital Organization Matsumoto Medical CenterNagano, Japan
Saigata Medical CenterNiigata, Japan
Katayama Medical ClinicOkayama, Japan
Tokyo Medical University HospitalTokyo, Japan
Tokyo Metropolitan Geriatric HospitalTokyo, Japan
National Center of Neurology and PsychiatryTokyo, Japan
Vilnius University Hospital Santariskiu ClinicVilnius, Lithuania
Hospital Angeles de Culiacán, Neurociencias Estudios Clínicos SCCuliacán, Mexico
Hospital Uni; Dr. Jose E. GonzalezMonterrey, Mexico
AVIX Investigación Clínica S.CMonterrey, Mexico
Hospital Universitario de SaltilloSaltillo, Mexico
Podlaskie Centrum PsychogeriatriiBialystok, Poland
NZOZ NEURO-KARD Ilkowski i Partnerzy Sp. Partn. LekPoznan, Poland
NEURO-CARE Sp. z o.o. Sp. KomandytowaSiemianowice Śląskie, Poland
Przychodnia Specjalistyczna PROSENWarsaw, Poland
Centrum Medyczne NeuroProtectWarsaw, Poland
OptimumWarsaw, Poland
Hospital Prof. Dr. Fernando Fonseca; Servico de NeurologiaAmadora, Portugal
Hospital Beatriz Angelo; Servico de NeurologiaLoures, Portugal
State Autonomous Healthcare Institution "Republican Clinical Neurological CenterKazan', Russia
State autonomous institution of healthcare Inter-regional clinical and diagnostic centerKazan', Russia
Institution of RAMS (Mental Health Research Center of RAMS)Moscow, Russia
SBEI of HPI The 1st Moscow State Medical University n.a. I.M. Sechenov of MOH of RFMoscow, Russia
SHI City Psychoneurological Dispensary #7Saint Petersburg, Russia
Russian Medical Military Academy n.a. S.M.Kirov; Neurology DepartmentSaint Petersburg, Russia
City Clinical Hospital # 2 n.a. V.I. RazumovskySaratov, Russia
University Medical Centre MariborMaribor, Slovenia
Chonnam National University HospitalGwangju, South Korea
Inha University HospitalIncheon, South Korea
Konkuk University Medical CenterSeoul, South Korea
Asan Medical CenterSeoul, South Korea
KyungHee Medical CenterSeoul, South Korea
Ewha Womans University Mokdong Hospital; Dept of NeurologySeoul, South Korea
Fundació ACEBArcelon, Barcelona, Spain
Hospital Universitari de Bellvitge; Servicio de NeurologiaL'Hospitalet de Llobregat, Barcelona, Spain
Hospital Sant Joan de Deu; Servicio de NeurologíaManresa, Barcelona, Spain
Hospital General De Catalunya; Servicio de NeurologiaSant Cugat del Vallès, Barcelona, Spain
Hospital Mutua De Terrasa; Servicio de NeurologiaTerrassa, Barcelona, Spain
Hospital Virgen del Puerto. Servicio de NeurologíaPlasencia, Caceres, Spain
Hospital Universitario Marques de Valdecilla; Servicio de NeurologíaSantander, Cantabria, Spain
Clinica Universitaria de Navarra; Servicio de NeurologíaPamplona, Navarre, Spain
Complejo Asistencial Universitario de Salamanca; Servicio de PsiquiatríaSalamaca, Salamanca, Spain
Hospital General Universitario de Albacete; Servicio de NeurologíaAlbacete, Spain
Hospital Vall d'Hebron; Servicio de NeurologíaBarcelona, Spain
Hospital Universitario de Burgos. Servicio de NeurologíaBurgos, Spain
Clinica Ruber, 4 planta; Servicio de NeurologiaMadrid, Spain
Universitario de La Princesa; Servicio de NeurologíaMadrid, Spain
Hospital Universitario 12 de Octubre; Servicio de NeurologiaMadrid, Spain
Hospital Regional Universitario Carlos Haya; Servicio de NeurologiaMálaga, Spain
Hospital Universitario Virgen de Arrixaca; Servicio de NeurologíaMurcia, Spain
Hospital Universitario la Fe; Servicio de NeurologiaValencia, Spain
Servicio de Neurología Hospital Viamed Montecanal.Zaragoza, Spain
Skånes Universitetssjukhus Malmö, MinnesklinikenMalmö, Sweden
Sahlgrenska Academy University,Neuroscience and Physiology;Departmt of Psychiatry and NeurochemistryMölndal, Sweden
Karolinska Uni Hospital, Huddinge; Dept. of Geriatric MedStockholm, Sweden
Universitäres Zentrum für Altersmedizin und RehabilitationBasel, Switzerland
Hacettepe University School of Medicine; NeurologyAnkara, Turkey (Türkiye)
Osmangazi University School of Medicine,Neurology DepartmentEskişehir, Turkey (Türkiye)
Istanbul University Istanbul School of Medicine; NeurologyIstanbul, Turkey (Türkiye)
Ondokuz Mayis University School of Medicine; NeurologySamsun, Turkey (Türkiye)
Regional mental hospital; Department of psychiatry, psychology and sexologyLviv, KIEV Governorate, Ukraine
National Medical Academy of Postgraduate Education named after P.L.Shupik; Neurology Department #1Kiev, Ukraine
D.F.Chebotarev Institute of Gerontology NAMS;Depart of Age Physiology&Pathology of Nervous SystemKiev, Ukraine
Royal Preston HospitalBlackburn, United Kingdom
Surrey and Borders NHS Foundation Trust; Brain Science Research UnitChertsey, United Kingdom
Coventry and Warwickshire Partnership NHS TrustCoventry, United Kingdom
St George's HospitalLondon, United Kingdom
Charing Cross HospitalLondon, United Kingdom
Manchester Royal InfirmaryManchester, United Kingdom
Campus for Ageing and VitalityNewcastle upon Tyne, United Kingdom
John Radcliffe HospitalOxford, United Kingdom