TerminatedPhase 3

221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease

NCT02477800

What is this trial?

Generating plain-language summary...

Am I eligible?

Generating eligibility summary...

What's involved?

Summarizing study design...

Where and how to apply

Primary location

St. Joseph's Hospital and Medical Center

Phoenix, Arizona, United States

+180 additional locations

View on ClinicalTrials.gov

Save this trial

Quick facts

Start date: 2015-08-13
Enrollment: 1,653 participants
Sponsor: Biogen
Purpose: treatment

Locations (181)

St. Joseph's Hospital and Medical CenterPhoenix, Arizona, United States
Center for NeurosciencesTucson, Arizona, United States
Neurology Center of North Orange CountyFullerton, California, United States
Senior Clinical Trials, Inc.Laguna Hills, California, United States
Torrance Clinical Research Institute, Inc.Lomita, California, United States
University of California - Los AngelesLos Angeles, California, United States
UCSF - Memory and Aging CenterSan Francisco, California, United States
California Neuroscience Research Medical Group Inc.Sherman Oaks, California, United States
Southern California Research LLCSimi Valley, California, United States
Institute for Neurodegenerative DisordersNew Haven, Connecticut, United States
Georgetown University HospitalWashington D.C., District of Columbia, United States
Brain Matters Research, Inc.Delray Beach, Florida, United States
Neuropsychiatric Research Center of Southwest FloridaFort Myers, Florida, United States
Jacksonville Center for Clinical ResearchJacksonville, Florida, United States
University of MiamiMiami, Florida, United States
Miami Jewish Health SystemsMiami, Florida, United States
Compass Research MainOrlando, Florida, United States
Palm Beach Neurological CenterPalm Beach Gardens, Florida, United States
Stedman Clinical Trials, LLCTampa, Florida, United States
USF Health Byrd InstituteTampa, Florida, United States
Meridien ResearchTampa, Florida, United States
Compass Research MainThe Villages, Florida, United States
Premiere Research InstituteWest Palm Beach, Florida, United States
Cleveland Clinic Florida - WestonWeston, Florida, United States
Alexian Brothers Neurosciences InstituteElk Grove Village, Illinois, United States
Advocate Lutheran General HospitalPark Ridge, Illinois, United States
Fort Wayne Neurological CenterFort Wayne, Indiana, United States
Indiana University School of MedicineIndianapolis, Indiana, United States
University of Kansas Medical Center Research Institute, Inc.Kansas City, Kansas, United States
Via Christi Research, a division of Via Christi Hospitals Wichita, Inc.Wichita, Kansas, United States
Baptist Health LexingtonLexington, Kentucky, United States
Brigham & Women's Hosp End/DbtBoston, Massachusetts, United States
Beth Israel Deaconess Medical CenterBoston, Massachusetts, United States
ActivMed Practices & ResearchMethuen, Massachusetts, United States
Donald S. Marks, M.D., P.C.Plymouth, Massachusetts, United States
Mayo ClinicRochester, Minnesota, United States
Washington UniversitySt Louis, Missouri, United States
Las Vegas Medical researchLas Vegas, Nevada, United States
Advanced Memory Research Institute of NJ, PCToms River, New Jersey, United States
Albany Medical CollegeAlbany, New York, United States
New York University Medical Center PRIMENew York, New York, United States
University of RochesterRochester, New York, United States
ANI Neurology, PLLC d/b/a Alzheimer's Memory CenterCharlotte, North Carolina, United States
Raleigh Neurology Associates, P.A.Raleigh, North Carolina, United States
Cleveland ClinicCleveland, Ohio, United States
Lynn Health Science InstituteOklahoma City, Oklahoma, United States
The Clinical Trial Center, LLCJenkintown, Pennsylvania, United States
University of PittsburghPittsburgh, Pennsylvania, United States
Northeastern Pennsylvania Memory and Alzheimer's CenterPlains, Pennsylvania, United States
Rhode Island Mood & Memory Research InstituteEast Providence, Rhode Island, United States
Butler HospitalProvidence, Rhode Island, United States
Medical University of South Carolina (MUSC)Charleston, South Carolina, United States
Neurology Clinic, PCCordova, Tennessee, United States
University of Tennessee Medical Center. KnoxvilleKnoxville, Tennessee, United States
Clinical Neuroscience Solutions, Inc.Memphis, Tennessee, United States
UT Southwestern Medical Center at DallasDallas, Texas, United States
Baylor College of MedicineHouston, Texas, United States
National Clinical Research Inc.-RichmondRichmond, Virginia, United States
Medical College of Wisconsin, Inc.Milwaukee, Wisconsin, United States
St Vincent's Hospital SydneyDarlinghurst, New South Wales, Australia
Central Coast Neurosciences Research, GosfordEast Gosford, New South Wales, Australia
Central Coast Neurosciences ResearchErina, New South Wales, Australia
KARA Institute for Neurological DiseasesNorth Ryde, New South Wales, Australia
Calvary Mater NewcastleWaratah, New South Wales, Australia
The Prince Charles HospitalChermside, Queensland, Australia
Royal Brisbane and Women's HospitalHerston, Queensland, Australia
Toowoomba Base HospitalToowoomba, Queensland, Australia
Box Hill HospitalBox Hill, Victoria, Australia
Austin HospitalHeidelberg, Victoria, Australia
Royal Melbourne HospitalParkville, Victoria, Australia
Neurodegenerative Disorders ResearchWest Perth, Western Australia, Australia
LKH - Universitaetsklinikum GrazGraz, Austria
Christian-Doppler-Klinik - Universitätsklinikum SalzburgSalzburg, Austria
Heritage Medical Research ClinicCalgary, Alberta, Canada
The Medical Arts Health Research GroupPenticton, British Columbia, Canada
UBC HospitalVancouver, British Columbia, Canada
Toronto Memory Program (Neurology Research Inc.)Toronto, Ontario, Canada
Toronto Sunnybrook HospitalToronto, Ontario, Canada
The Montreal Neurological InstituteMontreal, Quebec, Canada
McGill Centre for Studies in AgingVerdun, Quebec, Canada
CHU de Quebec - Hôpital de l' Enfant JésusQuébec, Canada
CCBR - Ålborg - DKAalborg, Denmark
CCBR - Ballerup - DKBallerup Municipality, Denmark
RigshospitaletKøbenhavn Ø, Denmark
CCBR - Vejle - DKVejle, Denmark
Hopital Louis Pasteur ColmarStrasbourg, Bas Rhin, France
CHU Strasbourg - Hôpital HautepierreStrasbourg, Bas Rhin, France
Groupe Hospitalier Pellegrin - Hôpital PellegrinBordeaux, Gironde, France
CHU Reims - Hôpital Maison BlancheReims, Marne, France
Hopital Neurologique Pierre WertheimerBron, Rhone, France
Groupe hospitalier Broca - La Rochefoucauld - La CollégialeParis, France
Groupe Hospitalier Pitie-SalpetriereParis, France
Praxis Dr. ScholzBöblingen, Baden-Wurttemberg, Germany
Aerztliche GemeinschaftspraxisOstfildern, Baden-Wurttemberg, Germany
Neuro MVZ StuttgartStuttgart, Baden-Wurttemberg, Germany
Klinikum der Johann Wolfgang Goethe-UniversitaetFrankfurt, Bavaria, Germany
Praxis Dr. med. BergmannNeuburg am Inn, Bavaria, Germany
Neurologische Gemeinschaftspraxis KasselKassel, Hesse, Germany
Klinische Forschung Hannover-Mitte GmbHHanover, Lower Saxony, Germany
Universitaetsklinikum Aachen AOeRAachen, North Rhine-Westphalia, Germany
Universitaetsklinikum Bonn AoeRBonn, North Rhine-Westphalia, Germany
Universitaetsklinikum KoelnCologne, North Rhine-Westphalia, Germany
Charite Universitaetsmedizin Berlin - Campus Benjamin FranklinBerlin, Germany
Azienda Ospedaliero Universitaria Ospedali RiunitiTorrette Di Ancona, Ancona, Italy
Fondazione Istituto G.Giglio di CefalùCefalù, Palermo, Italy
Azienda Ospedaliera Ospedali Riuniti di BergamoBergamo, Italy
Azienda Ospedaliera Spedali Civili di BresciaBrescia, Italy
Azienda Ospedaliero Universitaria San MartinoGenova, Italy
Ospedale San RaffaeleMilan, Italy
Casa di Cura del PoliclinicoMilan, Italy
Azienda Ospedaliera Universitaria "Federico II"Naples, Italy
Seconda Università degli Studi di NapoliNaples, Italy
Azienda Ospedaliero Universitaria PisanaPisa, Italy
Policlinico Universitario Agostino GemelliRoma, Italy
Azienda Ospedaliera Universitaria OO. RR. S. Giovanni di Dio e Ruggi D'AragonaSalerno, Italy
A.O.U. Senese Policlinico Santa Maria alle ScotteSiena, Italy
Research SiteChiba, Chiba, Japan
Research SiteInzai-shi, Chiba, Japan
Research SiteKurume-shi, Fukuoka, Japan
Research SiteAizuwakamatsu-shi, Fukushima, Japan
Research SiteAsahikawa-shi, Hokkaido, Japan
Research SiteSapporo, Hokkaido, Japan
Research SiteSapporo, Hokkaido, Japan
Research SiteAtsugi-shi, Kanagawa, Japan
Research SiteKamakura-shi, Kanagawa, Japan
Research SiteKawasaki-Shi, Kanagawa, Japan
Yokohama, Kanagawa, Japan
Research SiteYokohama, Kanagawa, Japan
Research SiteYokohama, Kanagawa, Japan
Research SiteKyoto, Kyoto, Japan
Research SiteNagaoka-shi, Niigata, Japan
Research SiteIruma-gun, Saitama, Japan
Research SiteKasukabe-shi, Saitama, Japan
Research SiteŌta-ku, Tokyo, Japan
Research SiteBunkyō City, Tokyo-To, Japan
Research SiteShinjuku-ku (I), Tokyo-To, Japan
Research SiteShinjuku-ku, Tokyo-To, Japan
Research SiteYamagata, Yamagata, Japan
Research SiteItabashi-ku, Japan
Research SiteItabashi-ku, Japan
Research SiteKiyose-shi, Japan
Research SiteKodaira-shi, Japan
Hospital Professor Doutor Fernando Fonseca, E.P.E.Amadora, Portugal
Hospital de BragaBraga, Portugal
Centro Hospitalar e Universitário de Coimbra E.P.ECoimbra, Portugal
CUF AlvaladeLisbon, Portugal
Hospital Beatriz ÂngeloLoures, Portugal
Campus Neurologico SeniorTorres Vedras, Portugal
Inha University HospitalIncheon, Gyeonggi-do, South Korea
Seoul National University Bundang HospitalSeongnam-si, Gyeonggi-do, South Korea
Gachon University Gil Medical CenterIncheon, South Korea
Asan Medical CenterSeoul, South Korea
Samsung Medical CenterSeoul, South Korea
Konkuk University Medical CenterSeoul, South Korea
Policlinica GuipuzcoaDonostia / San Sebastian, Guipuzcoa, Spain
Hospital de CrucesBarakaldo, Vizcaya, Spain
Fundacio ACEBarcelona, Spain
Hospital Clinic i Provincial de BarcelonaBarcelona, Spain
Hospital de la Santa Creu i Sant PauBarcelona, Spain
Clinica RuberMadrid, Spain
Hospital Universitario Dr. PesetValencia, Spain
Hospital Universitari i Politecnic La FeValencia, Spain
Changhua Christian HospitalChanghua, Taiwan
Kaohsiung Medical University Chung-Ho Memorial HospitalKaohsiung City, Taiwan
Kaohsiung Chang Gung Memorial HospitalKaohsiung City, Taiwan
National Cheng Kung University HospitalTainan, Taiwan
National Taiwan University HospitalTaipei, Taiwan
Chang Gung Memorial Hospital, LinkouTaoyuan County, Taiwan
Southmead HospitalBristol, Avon, United Kingdom
Re:Cognition Health LtdLondon, Greater London, United Kingdom
Charing Cross HospitalLondon, Greater London, United Kingdom
The National Hospital for Neurology and Neurosurgery CentreLondon, Greater London, United Kingdom
Salford RoyalSalford, Greater Manchester, United Kingdom
The University of EdinburghEdinburgh, Lothian Region, United Kingdom
Manchester Royal InfirmaryBlackburn, Merseyside, United Kingdom
The RICE CentreBath, Somerset, United Kingdom
Glasgow Memory Clinic LtdGlasgow, Strathclyde, United Kingdom
Stobhill ACH HospitalGlasgow, Strathclyde, United Kingdom
Ninewells HospitalDundee, Tayside Region, United Kingdom
Newcastle UniversityNewcastle upon Tyne, Tyne & Wear, United Kingdom
Kingshill Research CentreChippenham, Wiltshire, United Kingdom