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Not yet recruitingN/A

Real-time Continuous Glucose Monitoring Compared With Intermittent Continuous Glucose Monitoring in People With Type 2 Diabetes Treated With Insulin.

The objective is to compare the efficacy of TR-CGM versus isCGM in patients diagnosed with T2D who are treated with insulin and use CGM, as defined by time in range between 70 and 180 mg/dL. An open-label clinical trial will be conducted.

Bogotá, Colombia
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Suspended

Molecular and Clinical Profile of Diabetes Mellitus and Its Complications

Background: \- Family and twin studies have suggested that genetic factors influence approximately 50 percent of a person's susceptibility to type 2 diabetes. Recently, some of the genes involved in the development of type 2 diabetes have

Phoenix, Arizona, United States
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CompletedEARLY_Phase 1

Endothelial Function as a Marker for Blood Pressure Control Among Hypertensive Diabetic Patients

Our aim is to examine the influence of blood pressure and glycemic control together with N-acetylcystein utilization on the endothelia function of hypertensive diabetic patient.The study population will include 50 diabetic patient with unco

Multiple locations
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CompletedN/A

Comparison of Day and Night Closed-loop With Faster-acting Insulin Aspart With Insulin Aspart

The main objective of the study is to determine whether automated closed-loop using faster-acting insulin aspart will improve glucose control and reduce the burden of hypoglycaemia over a 23-hour period compared to insulin aspart under cond

Manchester, United Kingdom
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Not yet recruitingPhase 3

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

The purpose of this clinical study is to look into how well a study medicine called CagriSema helps children and adolescents living with diabetes lower their blood sugar and body weight. The study has 2 parts: in the first part participant

New Haven, Connecticut, United States+55 more
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CompletedN/A

Value-based Emotion-focused Educational Programme to Reduce Diabetes-related Distress

The purpose of the clinical trial is to evaluate the effectiveness of a relatively simple and short value-based emotion-focused educational programme in adults with type 2 diabetes (VEMOFIT) on diabetes-related distress, depressive symptoms

Multiple locations
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CompletedN/A

Effects of Inspiratory Muscle Training on Type 2 Diabetes Mellitus Patients With Inspiratory Muscle Weakness

The purpose of the study is to determine if inspiratory muscle training improves inspiratory muscle strength of type 2 diabetes mellitus patients with inspiratory muscle weakness.

Porto Alegre, Rio Grande do Sul, Brazil
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CompletedN/A

Effects of Functional Ingredients in an Acute Metabolic Challenge Context

After an energy-rich meal the blood levels of glucose and lipids undergo a marked temporary increase, triggering a wave of oxidative stress due to the appearance of excess free radicals in adipose and muscle tissues. Elevated postprandial h

Lund, Sweden
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CompletedPhase 2

A Study Evaluating the Safety, Tolerability, and Pharmacodynamic Effects of GLY-200 in Type 2 Diabetic Patients

This study is a Phase 2, randomized, double-blind, placebo-controlled, single-center study in adult patients with type 2 diabetes. It will evaluate the safety and tolerability of oral GLY-200.

Chula Vista, California, United States
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CompletedPhase 3

Safety and Efficacy Study of Albiglutide in Type 2 Diabetes

The purpose of this study is to determine whether albiglutide is effective in the treament of patients with type 2 diabetes.

Alabaster, Alabama, United States+261 more
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UnknownN/A

Effects of Eccentric Training on Glycemic Control and Quality of Life in Patients With Type II Diabetes Mellitus

Diabetes is defined by the level of hyperglycemia its a metabolic chronic disorder that furthur lead to life threatning medical conditions however, the prevalence of diabetes is rapidly increasing day by day in both developed and developing

Rawalpindi, Punjab Province, Pakistan
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Completed

Women and Risk of Type 2 Diabetes

This is a follow-up survey of women, 10-12 years after they were included in the population-based Stork Groruddalen study of pregnant women, primarily set up to study gestational diabetes and related health issues in pregnancy in a multieth

Oslo, Norway
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CompletedPhase 3

Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo

Study D5553C0003 is a 28-week, randomized, double-blind, active-controlled, multicenter, Phase 3 efficacy and safety study with 24-week and 52-week extension phases of simultaneous administration of exenatide once weekly (EQW) 2 mg and dapa

Birmingham, Alabama, United States+132 more
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CompletedPhase 1

Regulation of Endogenous Glucose Production by Brain Insulin Action

It is well known that the hormone insulin lowers blood glucose in part by acting directly on the liver and reducing hepatic glucose production. Animal studies have shown that the hormone insulin can act on the brain to indirectly lower gluc

Toronto, Ontario, Canada
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Completed

Hypoglycaemia (Low Blood Sugar) in Adults With Diabetes and Adrenal Failure

The purpose of this study is to measure how often low blood sugars occur in people who live with both adrenal insufficiency (AI) and diabetes and need to take insulin. People who live with AI need to take steroid replacement tablets every d

London, United Kingdom
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CompletedPhase 1

A Study to Test How a New Long-acting Insulin (Insulin Icodec) Works in the Body of People With Liver Disease

Participants will receive one insulin icodec dose, which will be administered in the morning of the day of dosing. The study will last for about 8 weeks.

Prague, Czechia+1 more
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CompletedPhase 2 / Phase 3

Low Glycemic Load Diets in Latino Children at Risk for Type 2 Diabetes

The purpose of this study are to: 1. compare two diet plans - a low-glycemic load (low-GL) diet and a low-fat diet.

Washington D.C., District of Columbia, United States
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TerminatedPhase 3

Safety and Efficacy of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

This trial is conducted in Asia, Europe and Oceania. The aim of this research study is to compare the efficacy of adding inhaled preprandial insulin to glimepiride compared to adding rosiglitazone to glimepiride for the treatment of type 2

St Leonards, New South Wales, Australia+25 more
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Completed

A Biobehavioral Model of Diabetes Risk in Chinese Immigrants

This prospective, longitudinal study of Chinese American immigrants will examine whether psychosocial factors (e.g., acculturative stress, social isolation, discrimination) are associated with markers of type 2 diabetes risk over time, and

Philadelphia, Pennsylvania, United States
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CompletedPhase 4

Baseline Oral Health Study: UnCoVer the Connections to General Health

Purpose: The Baseline Oral Health Health Study is a randomized controlled trial to evaluate the impact of regular, professional non-surgical Intensive Periodontal Therapy (scaling and root planing and optimal oral hygiene with associated pr

Chapel Hill, North Carolina, United States+1 more
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