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Completed

Is Carotid Intima-media Thickness Affected by A1C Variability?

This study was conducted to evaluate the effect of A1C variability on the progression of carotid artery intima-media thickness in type 2 diabetic patients.

Multiple locations
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CompletedPhase 4

ADIponectin and Asymmetric Dimethylarginine (ADMA) Level in Type-2 Diabetes Patients After 12 Weeks of Treatment With GlimepiRide And Metformin Fixed Dose Combination

Primary Objective: To evaluate the change in plasma levels of adiponectin and Asymmetric Dimethylarginine (ADMA) in type 2 diabetes patients after 12 weeks of treatment with Amaryl-M Secondary Objectives: 1. To assess the role of Amaryl-

Jakarta, Indonesia
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CompletedPhase 3

Comprehensive Add on Study in Japan

The objective of the current study is to investigate the safety and efficacy of linagliptin (5mg / once daily) given for 52 weeks as add-on therapy to patients with type 2 diabetes mellitus and insufficient glycaemic control despite diet, e

Akishima, Tokyo, Japan+42 more
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RecruitingPhase 1 / Phase 2

cfMSC Therapy for Diabetes

The purpose of this study is to assess the feasibility, safety and clinical efficacy of the novel clonal fetal mesenchymal stem cell (cfMSC) therapy in patients with type II diabetes mellitus.

Shenzhen, Guangdong, China
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TerminatedPhase 2 / Phase 3

Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy in Patients With Types 1 and 2 Diabetes Mellitus

Diabetic Retinopathy is the leading cause of blindness in the world. Previous studies have documented beneficial effects of physiologic administration of pulsatile insulin on a variety of diabetic complications such as nephropathy, hyperten

Boca Raton, Florida, United States
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CompletedN/A

Perioperative Insulin, GIK or GLP-1 Treatment in Diabetes Mellitus

The incidence of diabetes mellitus type II is increasing. More and more patients who need surgery have diabetes mellitus type II.

Amsterdam, Please Select, Netherlands+2 more
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Unknown

Sleep Apnea in Look AHEAD (Action for Health in Diabetes)

This study will assess the effects of weight loss on sleep-disordered breathing (SDB) in 120 obese, type 2 diabetics with obstructive sleep apnea (OSA) from four Look AHEAD sites. Changes in SDB will be compared between subjects randomized

New York, New York, United States+3 more
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Active, not recruiting

The Hong Kong Diabetes Biobank

Asia is in the midst of an epidemic of diabetes. Epidemiological figures suggest that there are more than 110 million people affected by diabetes in China, with a significant proportion of young adults already affected.

Shatin, Hong Kong
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CompletedPhase 4

Comparison of Premixed Insulins Aspart 30, Aspart 70 and Aspart on Postprandial Lipids

The aim of the study is to investigate meal-related treatment with either premixed Insulin Aspart 30, Aspart 70 and Aspart with regard to postprandial glucose, triglyceride and free fatty acids excursions after a standard breakfast and lunc

Graz, Austria
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Completed

ApoB48 Metabolism in Plasma and Interstitial Fluid

Postprandial increases in the levels of atherogenic chylomicron remnant lipoprotein particles have long been considered a presumable risk factor for the development of atherosclerosis with time, also in normolipidemic subjects. apoB-48 (Chy

Stockholm, Huddinge, Sweden
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CompletedN/A

The Role of Self-efficacy Program for Self-management of People With Type Diabetes Mellitus

The goal of this clinical trial is to learn if a self-efficacy program can improve diabetes self-management behaviors in adults with Type 2 Diabetes Mellitus attending primary health centers (Puskesmas) in Yogyakarta, Indonesia. The main qu

Yogyakarta, DI Yogyakarta, Indonesia
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UnknownN/A

Can Enhanced Glycemic Control in Type II Diabetics Improve Myocardial Protection During Coronary Artery Bypass Grafting?

The investigators have previously demonstrated that the administration of insulin in the form of an infusion with additional sugar and potassium may improve cardiovascular performance and reduce biochemical evidence of heart muscle injury i

Birmingham, West Midlands, United Kingdom
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CompletedPhase 2

Evaluation of the Effect on Glucose Control and the Safety and Tolerability of AC2993 in Patients With Type 2 Diabetes Mellitus

This is a multicenter, randomized, blinded, placebo-controlled, short-term, dose-response study to examine the effects on glucose control of AC2993 as compared to placebo in patients with type 2 diabetes. Patients will be individuals with t

Birmingham, Alabama, United States+32 more
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Not yet recruitingN/A

Taurine and Nitrate Supplementation on Thermoregulatory in T2DM

Anthropogenic warming is increasing the frequency and intensity of extreme heat events. Elevated temperatures raise the risk of mortality and hospital admissions, particularly among people with chronic illnesses such as type 2 diabetes mell

Multiple locations
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RecruitingN/A

Type 2 Diabetes Mellitus and Downhill Aerobic Exercise Training

The purpose of this study is to compare the effects of an 8-week supervised downhill walking training program, prescribed based on the 6-minute walk test, on functional capacity, peripheral muscle strength, and cardiovascular responses in i

Istanbul, Maltepe, Turkey (Türkiye)
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CompletedPhase 3

A Study to Assess Efficacy and Safety of ASP1941 in Diabetic Patients With Renal Impairment

This study is to assess the effect of renal function on the efficacy and safety of ASP1941 in type 2 diabetic patients with mild to moderate renal impairment.

Chugoku, Japan+7 more
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Completed

Daily Use of JARDIANCE® Tablets in Japanese Elderly Patients With Type 2 Diabetes Mellitus

Study to investigate the safety and efficacy of daily use of JARDIANCE® Tablets in Japanese elderly patients with type 2 diabetes mellitus.

Multiple Locations, Japan
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CompletedN/A

A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program

A pilot study titled "A Virtual Cardiometabolic Health Program for African Immigrants (The Afro-DPP Program) will be conducted to address the cardiometabolic of community-dwelling African immigrants who have multiple cardiometabolic risk fa

Baltimore, Maryland, United States
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UnknownPhase 3

A Study on the Efficacy and Gut Microbiota of Berberine and Probiotics in Patients With Newly Diagnosed Type 2 Diabetes

The purpose of this study is to conduct a multicenter randomized, double-blind, placebo-controlled clinical trial, evaluating the effects and change of gut microbiota after berberine and/or probiotics administration in patients with newly d

Shanghai, Shanghai Municipality, China
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CompletedPhase 1

Trial to Assess the Influence of 4 Weeks' Treatment With Linagliptin as Compared to Glimepiride and Placebo on Endothelial Function in Patients With Type 2 Diabetes Using FMD (Flow-Mediated Vasodilation)

The general aim of the present study is to investigate the impact of 4 weeks treatment with linagliptin (5 mg) on endothelial function in patients with type 2 diabetes mellitus. In the current trial this effect of linagliptin treatment on e

Neuss, Germany
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