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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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CompletedN/A

Empathy in Action: Sunshine Calls for Life With Diabetes

Randomized controlled trial of the effectiveness in managing diabetes and improving mental health through a telephonic layperson-delivered empathy and relationship-focused program for patients at a Federally Qualified Health Center (FQHC) a

Austin, Texas, United States+8 moreView details
CompletedPhase 1

Multiple Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes

BMS-820132 is an investigational new drug being developed by BMS for treating Type 2 diabetes. The purpose of this study is to test the safety/tolerability (potential side effects) of multiple doses of the investigational new drug, as well

Phoenix, Arizona, United States+4 moreView details
CompletedPhase 4

Does Pioglitazone Increase the Production of 15-EPI-Lipoxin A4?

Type-2 diabetes mellitus is a public health concern. Patients with type 2 diabetes mellitus are at high risk of developing cardiovascular complications.

Houston, Texas, United States+1 moreView details
TerminatedPhase 3

GALLANT 6 Tesaglitazar vs. Pioglitazone

This is a 24-week randomized, double-blind, multi-center, active-controlled (pioglitazone) study of tesaglitazar (0.5 mg and 1 mg) in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run

Altoona, Pennsylvania, United States+73 moreView details
Completed

Empa PASS on Urinary Tract Malignancies

The aim of the study is to assess the risk of urinary tract malignancies in patients initiating empagliflozin (free or fixed dose combination) compared to patients initiating a dipeptidyl peptidase-4 (DPP-4) inhibitor.

Helsinki, Finland+2 moreView details
RecruitingN/A

CGM for Insulin-Treated T2DM During Post-Discharge Transition

The transition from inpatient care to the home setting is a critical phase for glycemic management, often associated with decreased adherence and deterioration of glycemic control. This multicenter, randomized, open-label, controlled trial

Shanghai, China+3 moreView details
TerminatedN/A

Modulating Effects of Oil Palm Phenolics in Uncontrolled Insulin-treated Type 2 Diabetes Mellitus

Study reported that providing Oil Palm Phenolics to Nile rats blocked diabetes progression in this spontaneous diabetes model. The present study aims to determine the beneficial effects of Oil Palm Phenolics in uncontrolled insulin treated

Seberang Jaya, Pulau Pinang, MalaysiaView details
Completed

Diabetes Footcare Companion App for Patients and Carers

Diabetes education and self-management support can be delivered via mobile phones. This protocol aims to assess the feasibility and acceptability of Well Feet, a conversational agent, as a diabetic foot care companion.

Singapore, Singapore+1 moreView details
CompletedPhase 3

Switching From Insulin Glargine to Insulin Degludec in Subjects With Type 2 Diabetes Mellitus (BEGIN™)

This trial is conducted in the United States of America (USA). The aim of this clinical trial is to assess the implications of switching from insulin glargine (IGlar) to insulin degludec (IDeg) in subjects with type 2 diabetes mellitus.

Goodyear, Arizona, United States+26 moreView details
Not yet recruiting

Assessment of Cognitive Function and Functional Performance in Patients With Type 2 Diabetes

Diabetes is a chronic metabolic disease that is becoming a growing public health problem worldwide, affecting people's lives in many ways. It is characterized by impaired carbohydrate, lipid, and protein metabolism associated with insuffici

Istanbul, Turkey (Türkiye)View details
CompletedN/A

Metabolic, Physical Responses To Exercise In Patients With Type 2 Diabetes Mellitus

The aim of this study is to compare the effects of high intensity interval exercise and moderate intensity continuous exercise on metabolic parameters, physical measures, fitness level, body composition and miRNA-143 level in patients with

Denizli, Turkey (Türkiye)+1 moreView details
CompletedPhase 2

A 12-week Study To Evaluate PF-06291874 Once a Day in Adults With T2DM Inadequately Controlled On Metformin

The purpose of this study is to determine whether PF-06291874 is effective in the treatment T2DM

Anaheim, California, United States+37 moreView details
UnknownN/A

Sodium Glucose Cotransporter-2 Inhibitors and Salt-sensitivity in Type 2 Diabetes

The goal of this interventional study is to test whether sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce the effects of high dietary sodium intake in patients with type 2 diabetes. Participants will undergo a dietary intervention

Pisa, PI, ItalyView details
CompletedPhase 1

Phase 1 Multicenter, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Response of PE0139 Injection in Adult Subjects With Type 2 Diabetes Mellitus

This study is a first-in-human randomized, double-blind (Investigator and subject), placebo controlled single ascending dose study that will enroll approximately 40 (6 active/2 placebo per dose group) adult male and female subjects with Typ

Anniston, Alabama, United States+2 moreView details
TerminatedN/A

Renal Denervation Therapy for Resistant Hypertension in Type 2 Diabetes Mellitus

To demonstrate the efficacy of renal denervation therapy in treating resistant hypertension and its effect on glucose metabolism in patients with type 2 diabetes mellitus

Hong Kong, Hong KongView details
CompletedPhase 3

The Efficacy and Safety of DWP16001 in Combination With Metformin in Patients With Type 2 Diabetes.

Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of DWP16001 in Combination with Metformin in Patients With Type 2 Diabetes Mellitus who Have Inadequate Glycemic Control on Metformin Alone.

Soeul, South KoreaView details
Unknown

Microalbuminuria as a Cardiovascular Risk Factor (PRECISED Substudy)

Microalbuminuria (MA) is an independent cardiovascular risk factor in diabetic and non-diabetic subjects. However, in the setting of type 2 diabetes, microalbuminuria could be a marker of either early diabetic nephropathy or diffuse endothe

Barcelona, SpainView details
CompletedN/A

Effects of BKR-017 on Insulin Resistance in Type 2 Diabetes Patients

The purpose of this study is to evaluate the effect of BKR-017 on insulin resistance in type 2 diabetes (T2D) subjects during 28 days of active test product administration.

Baton Rouge, Louisiana, United StatesView details
TerminatedPhase 3

A Study to Evaluate ITCA 650 for the Treatment of Type 2 Diabetes in Patients With High Baseline HbA1c

An 39-week plus extensions, open-label study to estimate the reduction in HbA1c in patients with initial HbA1c \>10% \</=12% who are treated with ITCA 650 20 mcg/day for 13 weeks followed by ITCA 650 60 mcg/day for 26 weeks plus optional 26

Birmingham, Alabama, United States+50 moreView details
Completed

Comparing the Clinical Characteristics of Male LADA, T1DM and T2DM Patients

Diabetes is a common chronic disease in most parts of the world. Diabetes-related complications are harmful to the human body.

Shanghai, Shanghai Municipality, ChinaView details
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