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Completed

Wearable Sensors and Artificial Intelligence for Carbohydrate Counting

This is a one-group pilot study where Chinese immigrants who are English speaking with T2D from NYU Langone Health and NYU Brooklyn Family Health Center (Sunset Park) will be recruited.

New York, New York, United StatesView details
Completed

Nutritional Rehabilitation and Sleep Apnea in the Obese

In obese patients, the prevalence of obstructive sleep apnea (OSA) is around 40% in men and 30% in women. Weight loss after bariatric surgery significantly improves OSA, with 75% of patients having a reduction in OSA severity or becoming no

Grenoble, FranceView details
CompletedPhase 2

Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Partial Lipodystrophy (FPL)

This is a single-center, open-label study to evaluate the efficacy of AKCEA-ANGPTL3-LRx for reduction of fasting triglycerides in participants with familial partial lipodystrophy.

Ann Arbor, Michigan, United StatesView details
CompletedN/A

Long-term Resveratrol and Metabolism

The main objective of the study is to investigate if 6 months resveratrol supplementation can improve glucose tolerance in overweight/obese individuals. As secondary objectives we want to investigate whether resting energy metabolism, intra

Maastricht, Limburg, NetherlandsView details
WithdrawnPhase 3

SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

This study compares the effect and safety of 2 dose schedules for semaglutide (study medicine) in people with type 2 diabetes previously treated with a diabetes medicine similar to semaglutide. The study will also evaluate the use of a new

Buena Park, California, United States+24 moreView details
CompletedPhase 3

Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Japanese Patients With Type 2 Diabetes Mellitus

Two independent study parts (i.e. Part A and Part B) are included in this trial.

Aichi, Kasugai, Japan+82 moreView details
Not yet recruitingN/A

Effect of Prebiotics in Saudi Adults With Type 2 Diabetes

This study will explore how a natural food ingredient called oligofructose affects blood glucose levels, lipid profiles, inflammation biomarkers, and gut bacteria in Saudi adults with type 2 diabetes. Oligofructose is a type of dietary fibe

Riyadh, Saudi ArabiaView details
WithdrawnPhase 2

Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance

50% of Arizonans are diabetic or pre-diabetic resulting in $6.4 billion in health care and productivity costs. The severity and incidence of Type 2 Diabetes Mellitus (T2DM) is directly related to the hepatic lipid concentration.

Multiple locationsView details
CompletedN/A

Diabetes Scorecard Educational Intervention Study

The purpose of this study is to see if the use of a diabetic scorecard during clinic visits can improve glycemic control, blood pressure control, LDL-cholesterol, aspirin usage, and amount of exercise in adults over age 40 with uncontrolled

Washington D.C., District of Columbia, United StatesView details
CompletedN/A

Impact of SomaSignal Tests on the Choice of Glucose-lowering Medications

The purpose of this study is to learn more about using a proteomic test called the SomaSignal Cardiovascular (CV) Risk Test in Type 2 Diabetes (CVD-T2D) to improve medical care for patients.

Aurora, Colorado, United StatesView details
CompletedPhase 3

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study evaluated the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study was that the addition of ertugliflozin reduces hemoglobin A1C

Birmingham, Alabama, United States+103 moreView details
CompletedN/A

HOME COOKING: Health Empowerment Strategy in People With Type II Diabetes Mellitus

Currently, one of the health challenges in the field of public health is to improve the quality of life of people with metabolic diseases, using new strategies that allow to promote healthy eating habits. Within the new strategies that may

Donostia / San Sebastian, Guipuzcoa, SpainView details
CompletedN/A

Diabetes Prevention Among Post-partum Women With History of Gestational Diabetes

The purpose of the STAR-MAMA intervention is to develop a patient-tailored telephone-base counseling intervention for young Latino women who are at high risk of diabetes. The intervention will focus at the end of pregnancy and the 9 months

San Francisco, California, United StatesView details
Completed

Is it Possible to Screen for Type 2 Diabetes at Day 2 in Gestational Diabetes Mellitus Patients Postpartum?

Within 6 months of delivery, women who had gestational diabetes mellitus should be screened for type 2 diabetes with a fasting plasma glucose test and/or a 2-h postchallenge glycemia in a 75-g oral glucose tolerance test. However, not all w

Sherbrooke, Quebec, CanadaView details
TerminatedPhase 1

Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 Diabetes

An increase of blood flow and capillary permeability decrease the impact of an endothelial barrier for glucose and insulin allowing them to reach their target cells in peripheral insulin sensitive organ in the human body. It is well known t

Gothenburg, SwedenView details
Completed

Establishment of the Human Intestinal and Salivary Microbiota Biobank- Diabetes

This is a prospective, clinical, monocentric study aimed to collect biological samples and study microbiota from subjects suffering from type 1 diabetes mellitus, subjects suffering from type 2 diabetes mellitus and from healthy volunteers.

Perugia, ItalyView details
CompletedPhase 4

Effects of Sequential Treatment Based on Lina/MET After Short-term Intensive Insulin in Newly Diagnosed Type 2 Diabetes

Short-term intensive insulin therapy(SIIT) is able to reverse β cell dysfunction and induce glycemic remission in patients with newly diagnosed type 2 diabetes. However, proportion of patients with response gradually decreases over time.

Guangzhou, Guangdong, ChinaView details
CompletedPhase 4

Insulin Glargine (Lantus) vs Sulfonylurea (SU) for BETA Cell Function (BETA Study)

Primary objective: To compare long-term glycemic control and preservation of beta cell function when basal insulin or sulfonylurea is added on metformin in the early Type 2 Diabetes Mellitus patients Secondary objective: To assess the ch

Seoul, South KoreaView details
CompletedN/A

Exercise-meal Timing and Postprandial Glucose Control

Physical activity helps maintain optimal postprandial blood glucose control. However, there is a lack of clear information regarding the optimal meal-activity timing required to maximize blood glucose control.

Edgbaston, West Midlands, United KingdomView details
RecruitingPhase 1 / Phase 2

A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes Mellitus

This is a Phase 1/2a double-blind dose-escalating study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single and multiple doses of ARO-ALK7 in adult participants with obesity without Type 2 Diabete

Morayfield, QLC, Australia+7 moreView details
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