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Glycemic Control and Retinal Microvascular Changes

The goal of this prospective, observational study is to compare in the association of glycemic control and retinal microvascular changes in patients with type 2 diabetes mellitus (T2DM) without diabetic retinopathy (DR). The main question i

Goyang-si, Republic of Korea, South KoreaView details
RecruitingN/A

Preventing T2DM After GDM With Immediate Postpartum Screening

The overall goal of this proposal is to create and test an implementation protocol for in-hospital immediate postpartum diabetes screening for postpartum patients with pregnancies affected by GDM.

Worcester, Massachusetts, United StatesView details
TerminatedPhase 3

Use of an Investigational Digital Therapeutic in Patients With Type 2 Diabetes

BT-001 is a software program intended to help patients with type 2 diabetes, under the guidance of their physician, improve glycemic control (i.e., levels of blood sugar). The BT-001 software delivers a type of behavioral therapy to patient

Plano, Texas, United StatesView details
CompletedPhase 1

Bioequivalence/Food Effect - Saxa/Dapa Dual Fixed Dose Combination (FDC)

The purpose of this study is to demonstrate the bioequivalence (BE) of Saxagliptin and Dapagliflozin from a 2.5-mg Saxagliptin/5-mg Dapagliflozin FDC tablet after oral administration relative to 2.5-mg Saxagliptin and 5-mg Dapagliflozin tab

Multiple locationsView details
TerminatedPhase 3

GALLANT 6 Tesaglitazar vs. Pioglitazone

This is a 24-week randomized, double-blind, multi-center, active-controlled (pioglitazone) study of tesaglitazar (0.5 mg and 1 mg) in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run

Altoona, Pennsylvania, United States+73 moreView details
CompletedN/A

Differing Completion Rates of DIABETES Education on Patient Reported Outcomes

The goal of this clinical feasibility trial is to test the impact of differing completion rates of a face-to-face diabetes self-management education programme on patient-reported outcomes measuring self-care, diabetes distress and quality o

St Helens, United KingdomView details
CompletedN/A

Use of Control-IQ Technology 2.0 in Adults, Children, and Preschoolers With Type 1 Diabetes

The goal of this clinical trial is to assess safety of and explore glycemic outcomes with Control-IQ technology 2.0 in adults, children and preschoolers with type 1 diabetes.

Aurora, Colorado, United States+3 moreView details
UnknownN/A

Impact of Body Composition and Exercise on Clinical, Metabolic and Molecular Parameters in Type 2 Diabetics in Qatar

The prevalence of type 2 diabetes (T2DM) is increasing sharply around the world and obesity and sedentary lifestyles are driving the epidemic. Obesity is often, but not always present in patients with T2DM.

Doha, QatarView details
CompletedPhase 4

Drug Interaction of Vildagliptin (LAF237) With Voglibose in Japanese Patients With Type 2 Diabetes

This study will evaluate the effect of voglibose on the pharmacokinetics and pharmacodynamics of vildagliptin in Japanese patients with type 2 diabetes.

Tokyo, JapanView details
CompletedN/A

Effectiveness of Buerger Allen Exercise Among Type 2 Diabetes Mellitus Patients With Foot Ulcer

This study was conducted to determine the effect of Buerger Allen exercises on lower extremity perfusion and wound healing in patients with foot ulcer type 2 diabetes. The Buerger Allen exercise is a specific exercise that aims to improve c

Ankara, Çankaya, Turkey (Türkiye)View details
CompletedN/A

INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers

Previous studies have indicated increased vasopressin due to hypertonic saline infusion impairs glucose regulation. The current study will examine the effect of low water intake on glucose regulation.

Phoenix, Arizona, United StatesView details
By invitation

Clinical Decision Support With Continuous Glucose Monitoring Data for Managing Type 2 Diabetes

The goal of this project is to see if an electronic health record (EHR)-based smart order set with continuous glucose monitoring data to provide decision support can improve blood sugar management in people with type 2 diabetes (T2D) using

Minneapolis, Minnesota, United StatesView details
CompletedN/A

Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy

The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms. The variables of contrast se

Tehran, IranView details
CompletedPhase 1

4 Week Treatment With Three Oral Doses of BI 10773 in Patients With Type 2 Diabetes

Primary objective: safety and tolerability of BI 10773 in male and female patients with type 2 diabetes Secondary objective: pharmacokinetics and pharmacodynamics of BI 10773

Berlin, Germany+2 moreView details
CompletedPhase 3

A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM

This study aims to evaluate the efficacy and safety of DBPR108 tablets in combination with metformin hydrochloride in the treatment of type 2 diabetes mellitus. A total of 210 subjects will be randomly assigned in a ratio of 2:1 to receive

Beijing, ChinaView details
Completed

GIP, GLP-1 and GLP-2 in Type 2 Diabetic Hyperglucagonemia

In order to investigate the mechanisms underlying the hyperglucagonemia characterizing patients with type 2 diabetes mellitus (T2DM) we wish to test the following hypothesis: Do pancreatic alpha-cells exhibit inappropriate glucagon response

Herlev, Herlev, DenmarkView details
CompletedPhase 3

Effects of Linagliptin on Left Ventricular Myocardial DYsfunction in Patients With Type 2 DiAbetes Mellitus and Concentric Left Ventricular Geometry

The primary objective of the study is to evaluate the effect of linagliptin 5 mg daily versus the corresponding placebo on the LV systolic function (measured by midwall shortening analysis) in patients with T2DM and a documented baseline co

Bergamo, BG, Italy+18 moreView details
CompletedN/A

Beneficial Effects of Korean Traditional Diets in Subjects With Hypertension and Type 2 Diabetes

This trial is being conducted to look for following changes when Korean traditional diets is taken in subjects with hypertension and type 2 diabetes: To evaluate the improvement of the controlling fasting blood glucose and glycated hemoglo

Jeonju, Jeollabuk-do, South KoreaView details
CompletedPhase 2

The Effect Effect of Empagliflozin on Oxidative Stress in Patients With Type 2 Diabetes

The purpose of this study is to investigate the effect of empagliflozin on oxidative stress in patients with type 2 diabetes. The association is examined by comparing the difference in oxidative modifications before and after 14 days treatm

Hellerup, DenmarkView details
RecruitingPhase 3

A Randomized, Double-blind, Multi-center, Active-controlled, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of THP-00101, THP-00102, and THP-00103 in Subjects With T2DM and Essential Hypertension

\[Primary Objective\] To demonstrate the superiority of the change in mean sitting systolic blood pressure (MSSBP) and hemoglobin A1c (HbA1c)on week 12 of the combination therapy of THP-00101 (dapagliflozin 10 mg) and THP-00102 (telmisartan

Seoul, South Korea+1 moreView details
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