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Completed

Description of the Reasons for Hospitalization of Patients With Parkinson's Disease Following Admission Through the Adult Emergency Department

The goal of this observational study is to investigate the causes of hospitalisation via emergency services in patients with degenerative parkinsonian syndromes. All causes of hospital admission through the emergency department among patien

Bobigny, Île-de-France Region, FranceView details
CompletedPhase 2

Repeated-Dose Oral N-acetylcysteine for the Treatment of Parkinson's Disease

The investigators are interested in evaluating the use of oral N-acetylcysteine (NAC) as therapy for Parkinson's Disease (PD) and measuring changes in brain and blood chemistry.

Minneapolis, Minnesota, United StatesView details
UnknownN/A

Subthalamic Steering for Therapy Optimization in Parkinson's Disease

Twenty patients with idiopathic Parkinson's disease (PD) will be included into this single center randomized controlled double-blind clinical trial (RCT) in a cross-over design. The treatment consists of two different stimulation settings u

Tübingen, Baden-Wurttemberg, GermanyView details
CompletedN/A

Effects of Gait Training With and Without PNF on Balance ,Gait and Activities of Daily Living in Parkinson's Patients

Proprioceptive Neuromuscular Facilitation (PNF) and gait training exercises are specifically used to treat balance, gait and functional activities in Parkinson s patients. PNF has been compared with gait training and balance training in oth

Lahore, Punjab Province, PakistanView details
CompletedPhase 3

The Efficacy, Tolerability and Safety of Donepezil (Aricept) in Parkinson's Disease Patients With Dementia

A randomised, double-blind, 3-arm parallel group study comparing Aricept® with placebo.

Hamburg, Hambug, Germany+3 moreView details
CompletedN/A

Effects of Hyperthermic Baths on Motor Symptoms of Parkinson's Disease

The aim of this study is to further evaluate the effects of seasonal variation and the aquatic thermal environment of hyperthermic baths (HTB) on the Motor Symptoms (MS) of Parkinson's Disease (PD), and whether the environmental temperature

Nanjing, Jiangsu, ChinaView details
Active, not recruitingN/A

Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery

This project assesses the effect of bifocal cross-frequency transcranial alternating current stimulation (tACS) combined with visual training to improve visual recovery and orchestrated oscillatory activity in stroke patients suffering from

Geneva, SwitzerlandView details
UnknownN/A

The Effect of Deep Brain Stimulation on Facial Expressions.

Whether Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS), a treatment commonly used to ameliorate the motor symptoms of Parkinson's disease (PD), affects on facial expressions is unclear. The purpose of this study was to investigate t

Hatay, Turkey (Türkiye)View details
UnknownN/A

fNIRS Studies of Music Intervention of Parkinson's Disease

Functional near-infrared spectroscopy (fNIRS) will be used to monitor neuronal activities and connectivity to elucidate the correlation between physiological changes within the brain and the benefits of music therapy for patients afflicted

Dalian, Liaoning, ChinaView details
CompletedEARLY_Phase 1

Stereotactic Transplantation of hAESCs for Parkinson's Disease

The purpose of this study is to evaluate the safety and efficacy of stereotactic transplantation of hAESCs for Parkinson's disease.

Shanghai, Shanghai Municipality, ChinaView details
CompletedPhase 4

Dopaminergic Modulation of Declarative Memory

The study investigates the effect of dopaminergic stimulation over declarative memory functions in Parkinson's disease (PD) patients. At this aim, 20 PD patients will receive declarative memory tasks in two different conditions: after 12-18

Rome, ItalyView details
WithdrawnPhase 2

Rajavtihi Neuronal Adult Stem Cells Project

To study the success of Oligodendrocyte progenitor cell culture project in Rajavithi Hospital to identify an unlimited clone human neuronal progenitor stem cells from the human brain in the Biomolecular Research Center. This study aims to p

Bangkok, ThailandView details
Recruiting

Molecular and Functional Imaging in Monogenic PD.

In this study, the investigators aim to find a biomarker of Parkinson's disease. This is done using imaging scans called Positron Emission tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Magnetic Resonance Imaging

Exeter, Devon, United KingdomView details
CompletedPhase 2

Study to Evaluate the Efficacy, Safety and Tolerability of PXT002331 (Foliglurax) in Reducing Motor Complications of Levodopa Therapy in Parkinson Disease's Patients

This will be a double-blind, randomised, placebo-controlled parallel-arm phase II proof of concept in subjects with PD treated with a stable dose of levodopa who are experiencing both end-of-dose wearing off and Levodopa-Induced Dyskinesia

Innsbruck, Austria+44 moreView details
CompletedN/A

Using Advanced Driver Assistance Systems (ADAS) as an Intervention Strategy for Drivers With Parkinson's Disease

Parkinson's disease (PD) impacts an individual's fitness to drive in a number of ways that increase the crash risk in this population. Current vehicle automation technologies are available, that although designed for the general public, may

London, Ontario, CanadaView details
CompletedN/A

Low Vision Occupational Therapy in Parkinson's Disease

The primary aim of this study is to determine whether low-vision occupational therapy improves quality of life in Parkinson's Disease (PD) patients. Low-vision occupational therapy has not been previously studied in PD patients, and we susp

Birmingham, Alabama, United StatesView details
UnknownPhase 4

Emotion, Mood and Executive Function in Parkinson's Disease (PD)

The current study aims to assess the effect of an 8 week Azilect treatment (as adjunct therapy to levodopa) on affect perception and emotional expressiveness in a double-blind placebo-controlled study.

Bochum, North Rhine-Westphalia, GermanyView details
UnknownEARLY_Phase 1

A Study on the Safety and Tolerability of RGL-193 in Patients With Advanced Parkinson's Disease

A safety study in patients with Parkinson's disease.

Suzhou, Jiangsu, ChinaView details
Active, not recruitingN/A

The Effects on Physical Activity on Mitochondrial Function in Skin Fibroblasts in Patients with Parkinson's Disease.

The aim of this study is to investigate the effect of physical activity on mitochondrial function in skin fibroblasts in patients with Parkinson's disease.

Barcelona, Catalonia, SpainView details
CompletedN/A

Relationship Between Dopaminergic Asymmetric Degeneration and Attentional Resources in Parkinson's Disease.

The researchers aimed to investigate the relationship between the asymmetric dopaminergic degeneration and the attentional resources in a group of patients with Parkinson's disease (PD).

Multiple locationsView details
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