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TerminatedN/A

Cardiac MR (CMR) in Cardiac Resynchronization Therapy Non-responders

Cardiac MR (CMR) will be used to assess myocardial activation and hemodynamics in patients with CRT. Goals are to demonstrate that * differences in Left ventricle (LV)- right ventricle (RV) pacing delays cause differences in myocardial act

Bonn, North Rhine-Westphalia, Germany
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CompletedN/A

Respiratory Variations for Predicting Fluid Responsiveness

Hypovolemia and acute circulatory failure affects more than 60% of patients hospitalized in intensive care or resuscitation. The volume expansion (VE) by fluid replacement therapy is the first treatment improve circulatory function.

Lille, Hauts-de-France, France
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CompletedN/A

EXercise InTervention in Heart Failure

This is a pragmatic, non-inferiority clinical trial, enrolling heart failure patients who will be randomized to a 12-week exercise training program either centre-based or home-based with telemonitoring. The impact of this intervention will

Porto, Portugal
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Completed

Contractile Reserve in Dyssynchrony: A Novel Principle to Identify Candidates for Cardiac Resynchronization Therapy

Cardiac resynchronisation therapy (CRT) has been documented to be a powerful treatment in patients with severe congestive heart failure. However, 30-40% of patients receiving a CRT are non-responders.

Leuven, Belgium+1 more
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Not yet recruiting

Impact of Iron Deficiency on Arrhythmic Events and Resting ECG Abnormalities in Patients Hospitalized With Heart Failure

The relationship between iron deficiency (with or without anemia) and arrhythmic risk or ECG abnormalities in hospitalized HF patients remains poorly characterized. This is particularly relevant in settings where advanced iron therapies (e.

Multiple locations
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CompletedPhase 3

Trial of Education and Compliance in Heart Dysfunction (TEACH)

The emphasis of this grant is to investigate ways to educate patients, not only to improve their knowledge about medications and diet that are important for better outcomes in heart failure, but also to try to understand how patients' belie

London, Ontario, Canada+1 more
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CompletedPhase 3

Exercise Training in ICD Recipients; Effect on Therapy Delivered, Depression and Anxiety

Interventional study in patients with ICD. Controlled, open intervention with exercise training.

Stavanger, Norway
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Completed

A National, Multicenter, Prospective, Observational Study to Assess Patient Characteristics, Treatment Algorithms and Disease Management of Hyperkalaemia Patients With Chronic Kidney Disease or Under Dialysis or With Heart Failure, Treated With Sodium Zirconium Cyclosilicate in Greece

This is a multicenter, observational, prospective, national study which includes patients with chronic kidney disease (CKD) under dialysis or not, or with heart failure (HF), treated with sodium zirconium cyclosilicate (SZC) as per Summary

Alexandroupoli, Greece+9 more
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CompletedPhase 4

Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy

The purpose of this study is to determine whether Nesiritide is more effective than nitroglycerin in modifying inflammatory and neurohormonal biomarkers without renal toxicity when proper infusion duration is administered.

Inglewood, California, United States
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UnknownN/A

Efficacy of an Advanced Care Planning Program in Advanced Heart FAilure

An "Advanced Planning Program of Health Decisions" (APPHD) is a process of reflection and relationship between the patient, their relatives and health professionals. It is based on respect for patient's autonomy, to engage patients in makin

Alcorcón, Madrid, Spain
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UnknownN/A

Remote Motivational Interviewing to Improve Self-care in Heart Failure Patients

The purpose of this study is to evaluate if motivational interviewing, performed remotely through videocalls, is effective to improve self-care in patients with heart failure

Alessandria, Italy
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CompletedN/A

The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care Patients

The aim of this study is to determine the level of pain and comfort associated with the implementation of virtual reality prior to nursing care in patients undergoing treatment in the intensive care unit. The research will be conducted in t

Çankırı, Turkey (Türkiye)
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CompletedPhase 4

Aspirin Withdrawal in Non-ischaemic Cardiomyopathy Study

Heart failure (cardiomyopathy) is a chronic condition in which the heart fails to function as a pump to move blood around the body. Aspirin has been traditionally used in heart failure because a tendency towards blood clots (including strok

Melbourne, Victoria, Australia
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TerminatedN/A

Dual Site Left Ventricular (LV) Pacing

The purpose of this study is to compare Dual LV (left ventricular) pacing to standard single LV pacing (BiV pacing) to see if Dual LV pacing: 1. Improves the way the heart's left ventricle functions 2.

Lake Geneva, Wisconsin, United States+1 more
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UnknownPhase 1 / Phase 2

Bosentan for Severe Mitral Valve Dysfunction

Vasoconstrictive signaling via endothelin receptors is not limited to primary pulmonary arterial hypertension, but has also been documented in secondary pulmonary hypertension due to congestive heart failure, including cardiac valve disease

Chalcis, Evoia, Greece
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CompletedN/A

Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program

This is a pilot randomized trial of the BAMS-HF (Balance, Aerobic capacity, Mobility and Strength in patients hospitalized for Heart Failure) Program versus usual care. The BAMS-HF Program pilot study is an initial step in eventually creati

Aurora, Colorado, United States
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TerminatedN/A

Neuromodulation of Inflammation and Vascular Function in Systolic Heart Failure

Heart failure (HF) is the leading cause of death in US. It is associated with abnormal vascular function termed endothelial dysfunction.

Oklahoma City, Oklahoma, United States
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Completed

High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure

Primary Aims 1. Evaluate the safety of high-dose spironolactone in combination of patiromer in acute decompensated heart failure patients.

San Antonio, Texas, United States
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CompletedPhase 4

Effects of Oral Sodium Bicarbonate Supplementation in Haemodialysis Patients (BicHD)

The purpose of the study is to investigate whether oral sodium bicarbonate supplementation to ensure a constant bicarbonate profile in haemodialysis patients will primarily lower predialysis potassium levels and secondary lead to improvemen

London, United Kingdom
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TerminatedN/A

Massage Therapy for Self-efficacy in LVAD Recipients

This pilot study evaluates the role of massage therapy to improve self-efficacy in patients with advanced heart failure who have recently received a left-ventricular assist device. In addition to usual care, half of the volunteer patients w

Washington D.C., District of Columbia, United States
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