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Completed

HBP Device EGM Data Collection

This is a single-arm, non-randomized, non-blinded study designed to collect device data in patients with permanent His bundle (HB) pacing lead and an existing Abbott permanent pacemaker, defibrillator, or cardiac resynchronization device. P

Huntsville, Alabama, United States+2 more
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Unknown

The Registry Evaluating Functional Outcomes of Resynchronization Management

The purpose of this study is to evaluate the functional outcomes of resynchronization management and to describe the patient psychosocial characteristics (depression ad anxiety) and associated outcomes with electrophysiologic device therapy

Elgin, Illinois, United States+1 more
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Completed

Shear Wave Elastography

In individuals needing a left ventricular assist device (LVAD), right heart failure (RHF) is a serious complication post-surgery, associated with worsened outcomes including mortality. However, predictors of decompensation after LVAD are no

Dallas, Texas, United States
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Unknown

BRING-UP 3 Heart Failure

The aim of this observational study is to assess the level of adherence to guideline recommendations regarding the management of patients with Heart Failure with Reduced Ejection Fraction (HFrEF); - the safety profile of the implementation

Casale Monferrato, AL, Italy+186 more
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Completed

Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE Trials

Patients will be approached to participate in this PAS after the HeartWare® Ventricular Assist System receives PMA approval for the indicated use as a bridge to cardiac transplantation.

Stanford, California, United States+24 more
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UnknownPhase 4

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

This study aims to compare two medications, acetazolamide and metolazone, along with loop diuretics, to see which one works better and is safer for patients with ADHF who have volume overload. By comparing these medications, we hope to lear

Giza, GZ, Egypt
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CompletedN/A

Assessment of Peripheral Veins Doppler Ultrasound for Diagnosis of Acute Right Heart Failure in Suspicion or Follow-up of Pulmonary Hypertension

Occurrence of acute right heart failure (ARHF) remains common during pulmonary hypertension (PH). Right atrial pressure (RAP) invasive measurement is the gold standard to diagnose ARHF in order to improve diuretic treatment management.

Poitiers, France
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UnknownN/A

Verizon Wireless - Sarasota Memorial Hospital Converged Health Management (CHM) For Heart Failure

The primary objective is to evaluate the impact on heart failure related quality of life when integrating a mobile health system, Verizon Wireless's Converged Health Management (CHM), into a subject's self-management of their heart failure

Sarasota, Florida, United States
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Unknown

Effect of Air Pollution in the Haifa Bay Area on Cardiovascular Morbidity and Mortality

The association between exposure to ambient air pollution and pulmonary disease has been well established.To date no study has assessed the burden of cardiovascular disease in Israel and its relation to ambient air pollution. The Haifa Bay

Multiple locations
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Completed

Decompensation Detection Study

To gather data and analyze decompensation events.

Multiple locations
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CompletedN/A

Heart Failure Medication Adherence

The objective of this investigation is to pilot test a medication in-hand intervention (Meds to Beds) compared to standard care for patients with heart failure (ICD-50\[all numbers\]). The study will evaluate if the intervention improves ad

Miami, Florida, United States
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Not yet recruitingN/A

SHARE Study: Social Chronic Heart Failure Person-centred cARE Intervention

People with Chronic Heart Failure (CHF) live with a complex situation that significantly affects their quality of life and well-being. Among the consequences of CHF that have the greatest impact on individuals is the effect it has on their

Pamplona, Navarre, Spain
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Unknown

Cardiac Mitochondrial Function in Explanted Human Hearts

Background: Treatment of heart failure has improved considerably in the past decades. Despite this improvement, the disease may progress into an end-stage ultimately leaving the physicians with no other treatment option than heart transpla

Multiple locations
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CompletedPhase 2

Hypertonic Saline Solution in Heart Failure

Patients with decompensated heart failure have high rates of mortality and morbidity despite recent improvements in diagnosis and treatment. Some aspects of their presentation such as renal failure, hyponatremia and congestive phenomena hav

São Paulo, São Paulo, Brazil
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CompletedPhase 4

Levosimendan in High Risk Heart Valve Surgery

Prospective, randomized, double blind study investigating the efficacy of levosimendan in heart failure after cardiac surgery. Study hypothesis: Levosimendan diminishes the need for adrenergic inotropic drugs and morbidity and may improve s

Kuopio, Finland
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RecruitingPhase 2

Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD

Arrhythmogenic right ventricular dysplasia (ARVD) is a rare cardiomyopathy characterized by the progressive replacement of cardiomyocytes by fatty and fibrous tissue in the right ventricle (RV). These infiltrations lead to cardiac electrica

Amiens, France+12 more
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TerminatedPhase 1

A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011)

Part I is a 3-period, active comparator-controlled, fixed sequence study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of MK-7145 compared to furosemide in participants with moderate-to-severe renal insufficien

Multiple locations
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CompletedN/A

Establishing Correlation Between Non-invasive Pulmonary Blood Pressure Readings and Swan-Ganz Results

Pulmonary hypertension (PH) is prognostic indicator in heart failure patients for poor outcome, however, it is challenging for monitoring. The current study is designed to explore whether data generated using Suremedix Device including a pu

Petah Tikva, Israel
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CompletedN/A

Tomography Positron Emission Assessment of the Impact of Cardiac Rehabilitation on Coronary Endothelial Function in Cardiac Failure

In patients with heart failure, the drive to the effort has demonstrated its safety and its interest. Patients with heart failure, endothelium-dependent peripheral vasodilatation is impaired by decreased activity of endothelial NO synthase.

Caen, France
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CompletedN/A

Randomized Controlled Trial to Test the Efficacy of Motivational Interviewing on Self-care

Introduction: Heart failure (HF) is characterized by an increasing prevalence and burden, representing a public health problem and a major cause of morbidity and mortality. Self-care is a cornerstone approach for optimizing therapy for pati

Lodi, Milan, Italy
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