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Completed

ECG Signal Collection From Long QT Syndrome, Wide QRS Complexes, Heart Failure, and Cardiac Resynchronization Patients

The purpose of this study is to collect surface electrograms from standard and several non-standard configurations in patients with long QT syndrome, heart failure, cardiac resynchronization therapy or wide QRS during a routine outpatient a

Papworth Everard, Cambridge, United KingdomView details
TerminatedN/A

Acute Hemodynamic Effects of Pacing the His Bundle in Heart Failure

Cardiac resynchronization therapy (CRT) with biventricular pacing (BVP) is indicated for patients with low ejection fraction and persistent symptoms of heart failure despite medical therapy and a wide QRS-complex, preferably with a left bun

Lund, SwedenView details
TerminatedPhase 3

European Trial of Dronedarone in Moderate to Severe Congestive Heart Failure

The purpose of this study is to assess the efficacy, tolerability and safety of dronedarone versus placebo in patients with symptomatic congestive heart failure (CHF) and left ventricular dysfunction (LVD) when added to evidence based treat

Hørsholm, Denmark+5 moreView details
Withdrawn

Chronic Obstructive Pulmonary Disease (COPD) in Patients Hospitalized for Acute Decompensated Heart Failure.

The presence of chronic obstructive pulmonary disease (COPD) would confer increased in-hospital mortality and length of hospital stay in patients with acute decompensated heart failure Assess the (1) prevalence of COPD in patients who are h

Multiple locationsView details
Unknown

Cardiovascular Imaging and Biomarker Analyses (CIBER)

"Cardiovascular Imaging and Biomarker Analyses (CIBER)" is a single-center, prospective and observational study evaluating the expression of novel biomarkers in patients undergoing cardiacvascular imaging within clinical routine care. It is

Mannheim, GermanyView details
RecruitingN/A

The DAPA-MEMRI Trial

Diabetes mellitus is among the top 10 causes of death worldwide with an increasing incidence. Patients with diabetes are at risk of developing heart failure which is characterised by significant changes in the heart muscle including scarrin

Edinburgh, Scotland, United KingdomView details
CompletedPhase 2

Impact of a Psychological Biofeedback-Relaxation Intervention on Clinical, Physical and Psychological Outcomes in Patients With Heart Failure

The purpose of this study is to determine the effect of biofeedback-relaxation combined with cognitive behavioral therapy on clinical, physical and psychological outcomes in patients with heart failure.

Lexington, Kentucky, United StatesView details
Unknown

Influence of Telemonitoring on the Management of LVAD-patients

The current study aims to investigate whether telemedical monitoring in patients with terminal heart failure and an implanted left ventricular assist device (LVAD) has an influence on LVAD-associated complications, hospitalization rates and

Essen, North Rhine-Westphalia, GermanyView details
Terminated

Global rEgistry on decongestioN Therapy Using Less invasivE UltraFiltration

In patients with advanced volume overload, minimally invasive ultrafiltration treatment in the acute phase can have a positive effect on clinical outcome. The aim is to collect treatment data in the context of a prospective registry of the

Heidelberg, Baden-Wurttemberg, Germany+18 moreView details
CompletedN/A

Improving Drug Use for Elderly Heart Failure Patients

The aims of this randomized, clinical trial are to develop and test a multileveled pharmacy-based program to improve the care of patients with heart failure. Risk factors for deterioration of heart failure will be determined including poor

Chapel Hill, North Carolina, United StatesView details
CompletedPhase 4

Systematic Withdrawal of Neurohumoral Blocker Therapy in Optimally Responding CRT Patients

The primary objective of this study is to demonstrate that in patients with recuperated/normalized left ventricular function, defined as an ejection fraction (EF) ≥ 50%, after implantation of cardiac resynchronization therapy, device treatm

Genk, Limburg, BelgiumView details
CompletedPhase 4

OptiVol® Care Pathway

Medtronic, Inc. is sponsoring the OptiVol® Care Pathway Study, a prospective, randomized, multi-center, post-market clinical trial in the United States.

Birmingham, Alabama, United States+107 moreView details
CompletedPhase 4

Effect of Passive Exercise on Systemic Endothelial Function in Elderly Patients With Chronic Heart Failure

The purpose of this study is to determine the effect of passive exercise on systemic endothelial function in elderly patients with chronic heart failure.

Kyoto, JapanView details
RecruitingN/A

Optimization of Cardiac Resynchronization Therapy by Non-Invasive Imaging of Cardiac Electrophysiology

The principal aim is to analyze total left and right ventricular activation time in different CRT device programming algorithms (SyncAV) measured by non-invasive electrophysiology

Innsbruck, Tyrol, AustriaView details
CompletedN/A

Acute Impact of Cardiac Resynchronization on Vascular Function (RVA-CRT)

Evaluation of the effect of short term activation/deactivation of biventricular pacing (BivP) of the CRT (during routine CRT interrogation) on vascular function as assessed via retinal vessel analysis (RVA), in patients treated with CRT.

Zurich, SwitzerlandView details
Completed

Honolulu Heart Program

To investigate coronary heart disease and stroke among American men of Japanese ancestry who were living on the island of Oahu in 1965. Morbidity and mortality surveillance of the original cohort is continuing.

Multiple locationsView details
RecruitingN/A

Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure

This clinical trial aims to compare the efficacy and safety of acetazolamide versus metolazone as adjunctive treatments to standard therapy in patients with acute decompensated heart failure (ADHF). ADHF is a life-threatening condition, and

Chak Four Hundred Fifty-four, Punjab Province, PakistanView details
Terminated

Evaluation of a Non-Invasive Electrocardiogram-Assisted Blood Pressure Monitor

Approximately one billion people suffer from hypertension worldwide. At least 10% of this population, that is, 100 million people, also suffers from associated chronic conditions namely, atrial fibrillation (AF), obesity, arterial stiffness

Ottawa, Ontario, CanadaView details
Unknown

Haemodynamic Effects of Dobutamine and Nitrite in LV Dysfunction

Patients with poor heart function can, in certain situations, have a further weakening of the heart muscle such that it becomes difficult to provide enough blood to the brain and other organs. In these cases, heart function can be supported

London, United KingdomView details
CompletedPhase 2

Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement

The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure estimation (S

Philadelphia, Pennsylvania, United StatesView details
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