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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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Not yet recruiting

Coronary Artery Disease in Hearts Donated for Transplantation

In spite of recent initiatives, in particular, the introduction into clinical practice of donation after circulatory death (DCD), there is a persistent mismatch between the demand for donor hearts for transplantation and their supply \[1\].

London, Middlesex, United KingdomView details
Active, not recruitingN/A

Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients

This study is a prospective, multi-center, pivotal trial to study the safety and efficacy of the WiSE-CRT System for Cardiac Re-synchronization Therapy.

Huntsville, Alabama, United States+67 moreView details
CompletedPhase 2 / Phase 3

Omega-3-Polyunsaturated Fatty-Acids (N3-Pufa) In Patients With Severe Chronic Heart Failure

To investigate whether n3-fatty acids have beneficial effects in chronic heart failure as regards circulatory function.

Vienna, AustriaView details
UnknownN/A

Effect of Whey Protein' Supplementation and Exercise in Patients With Heart Failure

The aim of this study is evaluate the effect of whey protein supplementation on muscle mass preservation, improvement of strength and quality of life, and inflammatory parameters in patients with heart failure NYHA I or II followed by a car

Rio de Janeiro, BrazilView details
UnknownPhase 4

Carvedilol in HF With Preserved EF

Beta-blockers improve clinical outcomes in heart failure and reduced ejection fraction (HFrEF); but not in those with preserved EF. Global longitudinal strain (GLS) is a prognostic factor independent of left ventricular ejection fraction (L

Seoul, Il-won, South Korea+1 moreView details
UnknownN/A

Effects of Neuromuscular Electrical Stimulation in Patients With Congestive Heart Failure

This study intends to treat patient with congestive heart failure that are maximized their pharmacological treatment and at heart transplant wait list. All patients in the treatment arm will receive electric muscular stimulation with a Russ

Campinas, São Paulo, BrazilView details
CompletedPhase 3

A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients

The purpose of this study is to evaluate the efficacy and safety of rivaroxaban compared with placebo in the prevention of symptomatic venous thromboembolism (VTE) events and VTE-related death post-hospital discharge in high-risk, medically

Birmingham, Alabama, United States+593 moreView details
CompletedN/A

Centers for Education on Research and Therapeutics - Heart Failure: Targeted Intervention Study

The objective of this study is to evaluate whether a quarterly feedback, education and performance improvement site-based intervention has a greater impact on quality performance and adherence to evidenced-based guidelines than existing on-

Durham, North Carolina, United StatesView details
CompletedN/A

Effect of 48 Hours of Treatment With the Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure

The purpose of this study is to determine whether 48 hours of glucagon-like-peptide-1 (GLP-1) infusion can improve heart function and alter substrate metabolism in non-diabetic patients with heart failure.

Aarhus, DenmarkView details
Completed

Determinants of Portal Vein Pulsatility Index

The pulsatile pattern of the portal vein is considered a marker of right ventricular dysfunction, but volemia may also contribute to this phenomenon. The separate influence of each factor remains debated, as the interplay between right vent

Bucharest, RomaniaView details
Recruiting

Implantable Cardioverter Defibrillator (ICD Registry)

The ICD Registry™ is a nationwide quality program that helps participating hospitals measure and improve care for patients receiving implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy devices with defibrill

Washington D.C., District of Columbia, United StatesView details
RecruitingN/A

Tailored Electronic Intervention to Improve Therapy in a Diverse Cohort of Patients With Heart Failure

Recent medical guidelines for the management of heart failure (HF) have established a combination of specific classes of medications as the best treatment for patients with heart failure with reduced ejection fraction (HFrEF). However, stud

Atlanta, Georgia, United States+3 moreView details
Completed

Acute Effect of Strength Training on Blood Pressure in Cardiac Patients

Moderate and heavy strength training exercise and the acute blood pressure rise in cardiac patient, how high?

Copenhagen, DenmarkView details
CompletedN/A

Heart Failure Re-admission Risk Estimation Using NICaS System With Comparison to Serum BNP Levels

HF represents a major burden in the developed world. Mortality and rehospitalization rates post-discharge in patients admitted with HF may be as high as 15%-30% within 60-90 days, respectively.

Tel Aviv, IsraelView details
CompletedPhase 1

Pharmacodynamic and Pharmacokinetic Study of BiDil Extended-release Capsules and Commercial BiDil Tablets

This study will investigate cardiovascular parameters using echocardiographic and pharmacokinetics during a daily dose of BiDil and BiDil Extended Release (XR) compared to a study drug free day.

Anniston, Alabama, United States+4 moreView details
CompletedPhase 2

Sodium Excretion of LCZ696 in Patients With Hypertension; Heart Failure and Healthy Volunteers

Assess mechanism of action of LCZ696 related to sodium excretion.

Moscow, RussiaView details
Not yet recruitingN/A

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

The goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiofrequency Ablation Enhancor System in patients with combined pre- and post-capilla

Multiple locationsView details
Active, not recruitingN/A

First in Human Clinical Investigation of the FIRE1 System in Heart Failure Patients (FUTURE-HF)

First in Human Clinical Investigation of the FIRE1 Device/System to evaluate the feasibility and safety of implanting the FIRE1 system in up to 50 stable HF patients.

Prague, Praha 5, Czechia+12 moreView details
UnknownPhase 3

Torsion Optimization to Reduce Symptoms and Improve Outcomes in Non-responders

Approximately 40% of resynchronization therapy recipients do not appear to clearly benefit. These patients are termed 'non-responders'.

Calgary, Alberta, CanadaView details
Completed

Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)

Effective chest compressions are essential to survival in an arrest patient receiving CPR (cardiopulmonary resuscitation). A challenge in providing effective chest compressions is frequent interruption of compressions.

Morgantown, West Virginia, United StatesView details
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