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Completed

Multimarker Approach for Acute Dyspnea in Elderly Patients Admitted in the Emergency Department

Elderly people constitute the largest proportion of emergency department (ED) patients, representing 12% of all ED admissions. The need for diagnostic tests or therapeutic interventions is much greater in this patient population.

Besançon, Franche-Comté, FranceView details
CompletedPhase 4

Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality

The purpose of this study is to determine whether intravenous iron supplementation using ferric carboxymaltosis (FCM) extends the time-to-first-event of heart failure hospitalisations and cardiovascular (CV) death and reduces hospitalisatio

Hamburg, Free and Hanseatic City of Hamburg, Germany+50 moreView details
RecruitingN/A

Cardiac Contractility Modulation in Chagas Heart Disease

Chagas disease is an endemic problem in Latin America, where millions of people are chronically infected with T. cruzi.

São Paulo, São Paulo, BrazilView details
CompletedPhase 2

Prevention of Cardiac Dysfunction During Breast Cancer Therapy

Breast cancer is the most common cancer among women. The modern post-surgery treatment with chemotherapy, immunotherapy, radiation and hormone therapy has improved the overall 5-years survival drastically.

Lørenskog, Norway+3 moreView details
RecruitingN/A

Telemedically Assisted Optimization for Heart Failure Patients Before Cardiac Surgery to Improve Perioperative Outcome

Patients with heart failure undergoing cardiac surgery face a significantly increased perioperative risk, yet no standardized strategy exists to mitigate this risk effectively. Current preoperative management relies on optimization of medic

Innsbruck, Tyrol, AustriaView details
Completed

DF4 Master Study (Safety and Efficacy Study)

The purpose of the study is to proof the safety and efficacy of the new ICD sytem (Iforia/Ilesto). The devices are available with DF-1 and DF4 connection.

Greifswald, GermanyView details
Active, not recruitingN/A

Exercise and Cardiac Stunning During HD

The purpose of this study is to determine the effect of a 12-week cycling during hemodialysis program on hemodialysis-induced myocardial stunning in adult individuals receiving hemodialysis.

Adelaide, South Australia, Australia+5 moreView details
TerminatedPhase 3

An Exploratory Sub-study for the RED-HF™ (Reduction of Events With Darbepoetin Alfa in Heart Failure) Trial

The purpose of Study 20060172 was to measure echocardiographic parameters and biomarkers in a subgroup of study subjects enrolled in Study 20050222 (the RED-HF Trial). This substudy 20060172 was terminated early due to feasibility constrain

Multiple locationsView details
Completed

Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery

Cardiac surgery with cardiopulmonary bypass exposes patients to the risk of post-operative acute kidney injury. In the specific setting of cardiac surgery, acute kidney injury is often of multifactorial origindue to particular haemodynamic

Bron, Rhône, FranceView details
Not yet recruitingN/A

The Effect of Education on Symptom Burden, Medication Adherence, and Nutritional Behaviour

This study aims to determine the effect of online education structured according to Pender's Health Promotion Model on symptom burden, medication adherence, and nutritional behaviour in patients with heart failure. The sample size was calcu

Merkez, Çanakkale, Turkey (Türkiye)View details
UnknownN/A

A Critical Pathway for Implantable Cardioverter-Defibrillators in Patients With Ischemic Cardiomyopathy

The purpose of this study is to develop and implement a critical pathway to identify patients with ischemic cardiomyopathy who are candidates for an implantable cardioverter-defibrillator (ICD). This study will also determine whether the us

Vancouver, British Columbia, CanadaView details
Not yet recruiting

Evaluation of Heart Failure Telemonitoring Eligibility Criteria

The aim of this study is to analyze the prognosis and evolution of patients after exclusion of CARDIAUVERGNE, a heart failure telemonitoring system at Clermont-Ferrand's hospital. The patients were included from 1st January 2023 to 31st Dec

Clermont-Ferrand, FranceView details
CompletedPhase 3

Levosimendan Versus Dobutamine for Renal Function in Heart Failure

Although inotropes have a favorable effect on central hemodynamics in patients with heart failure, their effect on renal hemodynamics is incompletely defined. The purpose of this study is to evaluate the efficacy of a 75 min intravenous inf

Gothenburg, SwedenView details
CompletedN/A

D2-EPG Study: Evaluation of New Sensing Circuitry and Capture Management

This is an acute, prospective, multi-center, non-randomized, investigational device exemption (IDE) clinical study.

Tampa, Florida, United States+4 moreView details
Completed

ECLS Versus IMPELLA™ as Bridge to LVAD (ECI-BLAD)

In this retrospective observational multicenter study the authors tested the hypothesis that the use of IMPELLA™ pump as bridge to bridge, by giving the opportunity of active rehabilitation, should improve patient's outcomes after the impla

Dijon, France+4 moreView details
CompletedN/A

Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients

Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they increase thei

Trondheim, NorwayView details
CompletedN/A

Adaptive Cardiac Resynchronization Therapy Study

The purpose of this study is to demonstrate the AdaptivCRT algorithm is at least as good as manual echo based optimization in regard to patient outcomes and cardiac performance

Huntsville, Alabama, United States+104 moreView details
Active, not recruitingN/A

Comparison of the Balloon-Expandable Edwards Valve and Self-Expandable CoreValve Evolut R or Evolut PRO System for the Treatment of Small, Severely Dysfunctional Surgical Aortic Bioprotheses. The 'LYTEN' Trial

The treatment with transcatheter aortic valve implantation (TAVI) of patients with small (≤23mm) surgical bioprostheses remains a challenge due to the increased transvalvular residual gradients and high rates of severe prosthesis-patient mi

Québec, Quebec, CanadaView details
Unknown

DevElopMent of Clinical PATHwaYs to the Diagnosis of Heart Failure With Preserved Ejection Fraction

Prevalence of heart failure with preserved ejection fraction (HFpEF) continues to increase in the developed world, likely because of the increasing life expectancy and an increasing number of elderly patients. Transthoracic echocardiography

Moscow, RussiaView details
CompletedN/A

Impact of the Aerobic Exercise Versus Exercise of Force on the Hemodynamic, Lipidic, Anthropometric and Psychological Variables of Patients With Cardiac Failure

Introduction and objectives: At the global level, cardiovascular diseases are the leading cause of mortality. Currently, rehabilitation programs are shown as an effective treatment to mitigate the effects of heart failure.

Multiple locationsView details
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