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Completed

Cost-effectiveness Analysis on Remote Monitoring for CIEDs in Japan by Using Systematic Review Methodology

2018 Revision of Health Reimbursement in Japan recognized non face-to-face diagnostics, such as Online Treatment, as the standard of care. There was a significantly additional cost for Cardiovascular Implantable Electronic Devices (CIEDs) M

Chiba, JapanView details
CompletedN/A

Myocardial Effects of NIV in OHS Patients

Chronic effects of noninvasive ventilation on myocardial function in patients with obesity hypoventilation syndrome (OHS) are scarcely understood. The aim of the present study was to evaluate the long-term effects of volume-targeted bilevel

Košice, SlovakiaView details
CompletedPhase 2

Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis

The prevention of atrial fibrillation related thromboembolism in the dialysis population is unclear. While the practice of anticoagulation appears favorable in patients with mild-to-moderate chronic kidney disease, no patients with severe c

Kingswood, New South Wales, Australia+27 moreView details
CompletedN/A

Inspiratory Muscle Training in Heart Failure

The aim of this study is to investigate the potential effects of inspiratory muscle training on cardiovascular, respiratory, physical, and psychosocial functions in patients with heart failure.

Izmir, Turkey (Türkiye)View details
CompletedN/A

Lung Water by Ultrasound Guided Treatment in Hemodialysis Patients (The Lust Study).

Volume overload is a leading risk factor for death and cardiovascular events in end stage renal disease patients maintained on chronic dialysis, particularly in those with myocardial ischemia and heart failure which represent a substantial

Bordeaux, France+18 moreView details
CompletedPhase 4

Effect of a New Formulation of Torasemide (Prolonged Release)on Myocardial Fibrosis in Patients With Heart Failure.

Torasemide is a loop diuretic (pyridine-sulfonylurea)with a wide experience in the treatment of oedema associated to heart failure, kidney or liver disease and either in the treatment of arterial hypertension (alone or combined with other a

Barcelona, Barcelona, Spain+22 moreView details
CompletedPhase 4

Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 3

This is a double-blind, randomized, two x two crossover (aprepitant vs placebo) during both initiation of Entresto, LCZ696, (50 mg dose) and at steady-state of Entresto (200 mg bid dose or the highest tolerated dose).

New Haven, Connecticut, United StatesView details
CompletedPhase 3

Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) Trial

To determine the effect of hawthorn extract 450 mg bid vs. placebo, in addition to standard medical therapy in ambulatory patients with NYHA class II to IV chronic heart failure on submaximal exercise as measured by the 6-minute walk test

Ann Arbor, Michigan, United StatesView details
Unknown

Evaluation of a Back-to-home Support Program for Hospitalized Patients for Heart Failure

The prevalence of heart failure is very high worldwide is between 1 and 2% in developed countries. The French Federation of Cardiology estimates that a million people are affected in France.

Paris, FranceView details
Recruiting

Seasonal Physical Activity in Patients With Heart Failure With Cardiac Implantable Electronic Devices

The aim of this observational study is to determine the effect of seasonal changes on physical activity levels in heart failure patients with cardiac implantable electronic devices. Patients with heart failure who have a cardiac implantable

Çorum, Turkey (Türkiye)View details
CompletedPhase 3

APAF: Assessment of Cardiac Resynchronization Therapy in Patients With Permanent Atrial Fibrillation

A suboptimal level of resynchronization (cardiac resynchronization therapy \[CRT\]) achieved in many patients with actual standards and techniques based on tissue-Doppler echocardiography could be more effective to obtain better CRT results

Lavagna, Genova, Italy+1 moreView details
UnknownN/A

Unmasking the dynAmic Component in functionaL mitraL rEGuRgitatiOn in Chronic Heart Failure

Background: Chronic heart failure (HF) is frequently accompanied by functional mitral regurgitation (FMR) caused by left ventricular (LV) remodeling and subsequent papillary muscle displacement resulting in mitral valve (MV) leaflet tether

Vienna, AustriaView details
RecruitingPhase 4

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Breast cancer is the most commonly cancer in women in the overall global population. According to the World Cancer Research Fund International, there were more than 2.25 million new cases of breast cancer in women in 2020.

Opole, Opole Voivodeship, Poland+3 moreView details
CompletedN/A

The Automated Fluid Shunt (AFS)in Chronic Congestive Heart Failure

A 28-week, feasibility study to investigate the safety and efficiency of the Automatic Fluid Shunt in patients with chronic congestive heart failure, ascites and diuretic resistance.

Gothenburg, SwedenView details
Unknown

NIRS for the Diagnosis and Prevention of Acute Renal Failure

This prospective study will take place at Hotel Dieu de France hospital in Lebanon. One hundred children undergoing cardiac surgery for congenital heart disease between May 2020 and May 2021 will be included.

Beirut, LebanonView details
Completed

Role of Sacubitril/Valsartan in the Improvement of Heart Failure With Reduced Ejection Fraction

This prospective study evaluates the mechanisms of benefit of sacubitril/valsartan in a population of outpatients with heart failure with reduced ejection fraction, to investigate the relationship between the effects on left ventricular eje

Pisa, ItalyView details
Completed

The Long-term Course of Moderate Tricuspid Regurgitation

To evaluate the long-term clinical outcome of a cohort of patients suffering from moderate tricuspid regurgitation (TR), regardless of its etiology.

Milan, ItalyView details
RecruitingPhase 2

Cyclosporine In Takotsubo Syndrome

The goal of this clinical trial is to investigate the impact of repetitive acute Cyclosporine A (CsA) bolus therapy in patients suffering from TTS with an elevated risk of impaired outcome. The main question it aims to answer is whether CsA

Bad Nauheim, Germany+23 moreView details
RecruitingN/A

Optimizing Beta Blocker Dosage in Women While Using the Wearable Cardioverter Defibrillator

The primary objective of this pilot study is to document the percentage achievement in effective HR control (average nighttime HR \< 70 bpm) during WCD use in a cohort of female patients with cardiomyopathy in an outpatient setting using co

Cincinnati, Ohio, United States+3 moreView details
CompletedN/A

Validation of the Peripheral Arterial Tone to Detect Sleep-disordered Breathing in Patients With Chronic Heart Failure

A prospective validation study: Level I-full night-polysomnography (PSG) versus a diagnostic device with measurement of the peripheral arterial tone (PAT) of patients with chronic heart failure (CHF) and sleep-disordered breathing (SDB).

Bad Oeynhausen, North Rhine-Westphalia, GermanyView details
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