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CompletedN/A

Online Cognitive Behavioral Therapy for Depressive Symptoms in Parkinson's Disease

More than 1 million people in Europe suffer from Parkinson's disease (PD), a brain disorder manifesting with a motor syndrome and several non-motor features. Neuropsychiatric symptoms, like anxiety and depression, are common in patients wit

Stavanger, Norway
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Not yet recruitingN/A

Comparing Integrative Midwife-led vs. Fragmented Inpatient Postpartum Care: Impact on Satisfaction and Transition to Motherhood

The goal of this clinical trial is to compare two different forms of postnatal care to find out which is most beneficial for mothers and their children after birth and with which they are most satisfied. One is a nurse-led, seperate model o

Vienna, State of Vienna, Austria
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CompletedN/A

Smart Light Therapy Glasses for Sleep and Mental Wellness

A pair of smart light therapy glasses (Lumos Glasses) was engineered to control the amount of blue light exposure at a person's eyes through a battery powered light source and nano-coating that reflect blue light. The research aims to study

Waterloo, Ontario, Canada
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CompletedN/A

Combined Antidepressant and Behavioural Intervention

A body of evidence from both animal and human research suggests that antidepressant drugs may induce early changes in emotional processing that interact with environmental factors to produce a later change in mood. This experimental medicin

Oxford, Oxfordshire, United Kingdom
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CompletedN/A

Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction

The goal of this clinical trial is to assess the acceptability, feasibility, and usability of the iACTforDGBI intervention among patients with Disorders of Gut-Brain Interaction (DGBI). The main question it aims to answer are: What are the

Örebro, Sweden
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Unknown

Morbidity and Mortality Among Dialysis Patients After Treatment for Depression

Morbidity and Mortality among Dialysis Patients after Treating Depression Objectives Our investigation has two objectives: 1. To assess whether treatment and recovery from depression decreases adverse clinical events in chronic hemodialy

Portland, Oregon, United States
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Unknown

Wormwood in Chronic Progressive Disorders With Reduced Appetite

Wormwood is approved herbal medicine for the treatment of reduced appetite in Germany (Registration No.: 1339.99.99). Reduced appetite is observed in many chronic health disorders such as old age, immune disorders and cancer.

Freiburg im Breisgau, Baden, Germany
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UnknownN/A

Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety

The current study intends to establish a prediction method and evaluation system for polycystic ovary syndrome (PCOS) complicated with affective disorder, such as depression and anxiety, through the epidemiological investigation. Randomized

Shanghai, Shanghai Municipality, China
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CompletedPhase 1

Relapse Prevention for Suicidal Dually Diagnosed Youths

The purpose of this study is to develop, refine, and pilot test an augmenting cognitive behavior relapse prevention intervention (CBT-RP) for suicidal, depressed, and alcohol/substance abusing adolescents. No hypotheses are being tested, bu

Durham, North Carolina, United States
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CompletedN/A

Cognitive Process-based Real-time fMRI Neurofeedback in MDD and Rumination

The purpose of this study is to assess the feasibility and efficacy of real-time fMRI neurofeedback for rumination.

Tulsa, Oklahoma, United States
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Not yet recruiting

Preoperative Anxiety and Depression Among Older Chinese Patients

A multicenter, cross-sectional study to characterize the clinical profiles of the Chinese elderly population and to determine the prevalence of preoperative anxiety and depression.

Multiple locations
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RecruitingPhase 2

Stratified Pharmacological Approaches for Regulating Circuit-Level Effects

This research study aims to understand how people with depression respond to the medication pramipexole and to determine whether clinical response differs depending on the function of specific circuits in the brain. The investigators hope t

Palo Alto, California, United States
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Not yet recruitingPhase 3

The Research of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression

The purpose of this study is to evaluate the efficacy and safety of Ammoxetine hydrochloride enteric-coated tablets in subjects with depression.

Multiple locations
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Completed

Smartphone Addiction in Cervicogenic Headache

Cervicogenic headache is a secondary headache disorder that originates from the cervical spine and often presents with pain radiating from the neck to the head, reduced functional capacity, and impaired quality of life. In modern society, p

Yozgat, Yozgat, Turkey (Türkiye)
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UnknownN/A

The Effect of Selective Serotonin Reuptake Inhibitor (SSRI) Treatment on Affective Symptoms and Fertility Treatment Outcome in Women Undergoing in Vitro Fertilization (IVF)

Women undergoing IVF show a high prevalence of depressive and anxiety symptoms. Furthermore, stress has harmful consequences on IVF and pregnancy outcomes.

Tel Aviv, Israel
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Unknown

Public Health Consequences of Covid-19

Aim of this observational study is to improve our understanding of the impact of Covid-19 on health. By an online questionnaire at least 60.000 people are invited by email to participate.

Geleen, South Limburg, Netherlands
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Completed

Intravenous Beta-blockade for Improvement of Autonomic Activity

Chronic beta-adrenoceptor blockade is known to improve outcome of high risk patients whereas amelioration of autonomic activity was demonstrated to be a major cause of outcome improvement. Therefore, perioperative beta-adrenoceptor blockade

Kiel, Schleswig-Holstein, Germany
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CompletedN/A

Effects of Acute Prucalopride Administration in Healthy Volunteers

This study will investigate whether administration of a single dose of the serotonin receptor subtype 4 (5-HT4) partial agonist prucalopride has effects on emotional processing and non-emotional cognition in healthy volunteers, compared to

Oxford, United Kingdom
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CompletedPhase 2

A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD

This is a double-blind, randomized, placebo-controlled, multicenter study comprised of 3 phases:screening (up to 2 weeks \[Day -15 to Day -2\]), In-Clinic Treatment (Day -1 to Day 2; including double-blind treatment \[Day 1\]), and post-tre

Little Rock, Arkansas, United States+20 more
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CompletedN/A

Physiological and Psychological Effects

Stress-related mental health problems such as depression, anxiety, and stress are common among young adults and are often linked to both psychological and physiological changes in the body. One of the key biological markers of stress is cor

Merkez, Bingöl, Turkey (Türkiye)
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