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Recruiting

Brain Imaging of Cognition Inn Schizophrenia and Depression

Schizophrenia and depression are among the most disabling disorders in all of medicine. Cognitive deficits play a key role in patients' disability, affecting their capacity to contribute actively to society by sustaining employment or acade

Ottawa, Ontario, Canada
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Unknown

The Association of Gut Microbes and Their Metabolites With Post-stroke Depression

In this study, the clinical data of patients with AIS were collected, 16s RNA was used to detect the composition and diversity of intestinal flora, and flow cytometry and mass spectrometry were used to detect intestinal flora-related metabo

Xuzhou, Jiangsu, China
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TerminatedPhase 4

Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression

The primary study comparing effectiveness for suicidal ideation and/or behavior of two antidepressant medications in depressed patients who have attempted suicide or are currently experiencing suicidal thoughts has been completed. A seconda

New York, New York, United States
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Unknown

Heterogeneous Distribution of Health Literacy and Emotional State on Patients With Functional Dyspepsia.

Patients with indigestion were often found in gastroenterology clinic, those who about 20 % was caused by organic, while the rest of patients are showed abnormal inspection, and these are so called functional dyspepsia. Functional dyspepsia

Taipei, Taiwan
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CompletedN/A

Task-Oriented Rehab With SaeboFlex: Impact on Independence, Visual Motor Skills, and Depression in Stroke Patients

Objective: The SaeboFlex orthosis is designed to assist individuals with upper extremity weakness in performing repetitive tasks. This study is planned to evaluate its effectiveness in improving upper extremity functions in stroke patients.

Istanbul, Turkey (Türkiye)
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Completed

The Neural Representation of Self in Depression Patients

To be aware of oneself as a unique entity in the world occurs early in human development and is the prerequisite of normal social functioning. The disturbance of self representation characterizes a variety of mental disorders such as autism

Multiple locations
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Recruiting

Evaluation of the Naturalistic User Experience of the Website "ich Bin Alles @Schule" (i Am Everything @school)

The aim of this study is to investigate the naturalistic user experience and acceptance of the German website "ich bin alles @Schule". This website for educational professionals offers information on depression and mental health of pupils.

Munich, Germany
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Recruiting

Long-term Follow-up of Depressive Disorders in Psychiatric Care

The project investigates long-term prognosis and predictors of treatment outcomes for difficult-to-treat depression in patients in secondary psychiatric care. The current patient cohort was collected in 2012-2021 in the study "Pharmacogenet

Lund, Sweden+1 more
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CompletedN/A

Activation of Young Men - Population-Based Randomised Controlled Trial

The aim of the study is to investigate different novel IC technologies for promoting physical activity and health and preventing obesity in young men. The purpose is to provide new evidence-based knowledge on the effectiveness of an ICT-bas

Oulu, Finland
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CompletedPhase 2

Incorporating Patient Treatment Choice to Improve Treatment Retention in Depressed Hispanics

This study will determine whether combination treatment driven by patient choice is better than standardized medication treatment at retaining and improving Hispanic patients with major depressive disorder.

New York, New York, United States
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Unknown

Longitudinal Ecological Study on Sleep-Wake Patterns in MDD Using Actigraphy

The proposed study will include a longitudinal ecological study (Study 1) and a randomised controlled trial (Study 2). The aims will be to (1) identify the sleep-wake profiles in individuals with Major Depressive Disorder (MDD) through clus

Shatin, Hong Kong
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CompletedN/A

Different Exercising Intensities and Frequencies of Exercise on Depressive Mood and Insomnia

Aerobic exercise intervention for depression was conventionally recommended three times weekly with moderate intensity in previous studies, but little is known about the training effect of aerobic exercise at low frequency and vigorous inte

Hong Kong, Hong Kong
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CompletedPhase 2

A Study to Evaluate the Efficacy and Safety of NBI-1070770 in Adults With Major Depressive Disorder

To evaluate the efficacy, safety, and tolerability of NBI-1070770 compared to placebo on improving symptoms of depression in participants with major depressive disorder (MDD).

Little Rock, Arkansas, United States+12 more
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RecruitingN/A

Internet Based Psychological Support

The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management. Together the three modules are called PATH.

Lebanon, New Hampshire, United States
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CompletedN/A

Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression

The COVID-19 pandemic has led to a mis/disinformation ecosystem that promotes divergent views of vaccine efficacy, as well as the legitimacy of science and medicine. Individuals are confronted with vaccine-related information from a multitu

New York, New York, United States
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RecruitingPhase 3

Efficacy of Statins Among Major Depressive Disorder

The goal of this clinical trial is to learn if drug Rosuvastatin 10 mg works to treat MDD in adults. It will also learn about the safety of Rosuvastatin 10 mg .The main questions it aims to answer are: Does Rusovastatin lower the score of

Cairo, Al Abbasia, Egypt
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CompletedN/A

The Effect of Transcranial Magnetic Stimulation Treatment on Microvasculature Stracture of the Retina and the Choroid

Transcranial Magnetic Stimulation (TMS) therapy is an approved and effective treatment option in treatment-resistant depression. The present study aims to investigate the effect of TMS treatment on microvasculature stracture of the retina a

Ankara, Ankara, Turkey (Türkiye)
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CompletedN/A

Stress Reactivity of Physical Stressor on Depression

Depressive elderly individuals have showed higher basal level of cortisol and lower level of dehydroepiandrosterone (DHEA). Moreover, changes on these hormone levels have also observed in reactivity of an acute stress, such as physical exer

Rio de Janeiro, Rio de Janeiro, Brazil
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CompletedPhase 4

ADAPT: Addressing Depression and Pain Together

The primary question addressed by this study is: Using a stepped care approach in primary care, what is the value of the combination of an antidepressant medication (Venlafaxine) and psychotherapy for seniors living with depression and chro

Pittsburgh, Pennsylvania, United States
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CompletedPhase 1

Relative Bioavailability (RBA) Study of LY03005 vs Pristiq®

The objective of this study is to evaluate relative bioavailability between 80 mg LY03005 oral tablets and 50 mg Pristiq® oral tablets after a single dose of each drug in a cross-over 2-period design under fasting condition in healthy subje

Eatontown, New Jersey, United States
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