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Completed

Using Responsible Artificial Intelligence (AI) to Predict Online Therapy Outcome and Engagement

This study is to develop AI-based models for the personalised prediction of treatment engagement and treatment outcomes in patients engaging in digital psychotherapy. A large, real-world dataset of patients in a digital psychotherapy progra

Basel, Switzerland
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CompletedN/A

COPE for Children With Asthma: Intervention for Children With Asthma

Children with a chronic condition are at a significantly higher risk for anxiety and depression than those without a chronic condition. Asthma is the most common childhood chronic condition.

Columbus, Ohio, United States
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CompletedN/A

Online Intervention to Prevent Perinatal Depression and Promote Breastfeeding

"SunnysidePlus" will functionally integrate a web based intervention targeting skills to promote and support breastfeeding, manage mood,and prevent depression. Sunnyside Plus will build upon the previously tested "Sunnyside" intervention wh

Chicago, Illinois, United States
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Recruiting

Neurosurgical Outcome Network

The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared. This study aims to assess outcomes and their predictors using measures agreed upo

Bergamo, BG, Italy+26 more
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CompletedN/A

Psychoeducational Intervention to Reduce Depressive Symptoms and Strengthen Mother-Infant Bonding

The study aims to evaluate the effectiveness of a psychoeducational intervention designed within the framework of the Watson Human Caring Model in reducing postpartum depressive symptoms and creating a stronger mother-infant bond. Specifica

Eskişehir, Odunpazarı, Turkey (Türkiye)
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CompletedPhase 4

12- Week Open Label Treatment of Refractory Bipolar Depression

1. Determine the change in symptomatology and function in refractory bipolar depression, when treated with combination of DEP+AZP for a period of 12 weeks 2.

San Antonio, Texas, United States
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CompletedN/A

Decreasing Youth Involvement in Violence in Burundi

The purpose of the current study is to examine the psychological well-being of youth within the context of participation in political violence during the 2015 election period in Burundi. In detail, the investigators are interested in foster

Bujumbura, Burundi
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CompletedN/A

SALSA (Health, Food and Sociability): Community Networks for Healthy Eating, Autonomy, and Social Interaction

Antecedents: Unwanted loneliness is associated with an increased risk of anxiety, depression, social isolation, and malnutrition. The SALSA project aims to establish mechanisms and create an ecosystem that enables healthcare and social serv

Manresa, Barcelona, Spain
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TerminatedN/A

Decision Making Tool for Firearm Storage

This is a one-arm pilot study testing the feasibility and acceptability of a decision aid about safe firearm storage.

Seattle, Washington, United States
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CompletedPhase 3

Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression

The study will evaluate the efficacy and safety of ITI-007 (Lumateperone) in patients diagnosed with Bipolar I or Bipolar II disorder having a major depressive episode. The study will be conducted in two parts, Part A and Part B.

Little Rock, Arkansas, United States+54 more
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CompletedN/A

The Efficacy and Cerebral Mechanism of Intradermal Acupuncture for Major Depressive Disorder

Major depressive disorder (MDD) is highly prevalent, affecting nearly 4% of the global population. Pharmacotherapy is the frontline treatment recommended by the guideline, but it also has some limitations such as delayed onset, inadequate r

Hangzhou, Zhejiang, China
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CompletedN/A

Competency-based Training in Problem Management Plus: a Randomized Controlled Trial

The proposed study in Nepal will evaluate if non-specialists participating in Equip-based Problem Management Plus training show greater competencies compared to non-specialists participating in standard Problem Management Plus training. The

Kathmandu, Nepal
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CompletedN/A

BA Trial for Co-Occurring Depression and Substance Use

A large proportion of people seeking treatment for drug and alcohol issues also have clinically significant depression symptoms. This combination of problems tends to have a negative impact on treatment and leads to poor health and disabili

Doncaster, South Yorkshire, United Kingdom
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Unknown

Anxiety and Depression in COPD; Prevalence, Detection and Prognosis

The current cohort study of 300 stable COPD patients aims to assess the following topics: * The prevalence of anxiety and depressive disorders in patients with COPD * The screening properties of Hospital Anxiety and Depression Scale in pat

Jessheim, Norway
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Not yet recruiting

Symptoms of Anxiety and/or Depression and SDM in Older Patients With CLTI

Mental health disorders are common in older people and are often unrecognised. Those living with mental health disorders who are being considered for vascular surgery have worse post operative outcomes, including longer length of hospital s

London, United Kingdom
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Completed

The Effect of Neuropathic Pain in Patients With Combat-related Extremity Injury

It has been suggested that veterans with chronic pain might be at increased risk for the development of depression, anxiety and post-traumatic stress disorder. To date, most of the published studies have focused on chronic pain as a whole,

Ankara, Cankaya, Turkey (Türkiye)
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CompletedPhase 4

Efficacy and Safety of Toluedesvenlafaxine Hydrochloride Extended-release Tablets in Somatic Symptoms of Depression

The purpose of this study is to evaluate efficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets in the treatment of somatic symptoms in depression, to provide evidence-based basis for clinical rational drug use.

Shanghai, Shanghai Municipality, China
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CompletedPhase 3

§ Procaine Periarticular Injections for Pain Reduction in Elderly With Osteoarthritis

§ The goal of this clinical trial is to assess the effect of periarticular procaine injections combined with physical therapy on joint pain in individuals 65 and older suffering from osteoarthritis of the hip or the knee. The main question

Bucharest, Romania
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CompletedN/A

Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects

The presented project is an open and controlled single-center prospective exploratory study, evaluating the metabolic concentrations in the ventral striatum (VS), the Anterior cingulate cortex (ACC) and the prefrontal cortex (PFC) on the le

Clermont-Ferrand, France
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TerminatedPhase 3

Treatment of Depression With Quetiapine

The purpose of this study is to examine the mood stabilizing and antipsychotic properties of quetiapine in the treatment of depression by comparing subjects who were randomly assigned to either quetiapine monotherapy, quetiapine and citalop

Chicago, Illinois, United States
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