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UnknownN/A

Targeting Adolescent Depressive Symptoms Via Brief, Web-Based Interventions

Major depression (MD) in youth is a serious psychiatric illness with extensive morbidity and mortality. The American Academy of Pediatrics recently released practice guidelines promoting primary care (PC)-based youth MD screening; however,

New York, New York, United States
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RecruitingN/A

ROSE in Sunset Park

The purpose of this study is to learn more about pregnant women's' experience with Reach Out, Stay Strong, Essentials for mothers of newborns (ROSE) and to evaluate the effectiveness of the ROSE program in preventing and reducing post-partu

New York, New York, United States
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Not yet recruitingN/A

Miles for Mental Health

Common mental health disorders, like anxiety and depression, are widespread among the American population. The prevalence of mental health disorders among adults continues has consistently increased from previous decades and is now a major

Multiple locations
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CompletedPhase 3

A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-01)

This study will evaluate the efficacy, safety, and tolerability of rapastinel 450 mg compared to placebo adjunctive to antidepressant therapy (ADT) in patients with major depressive disorder (MDD) who have a partial response to ADT.

Beverly Hills, California, United States+30 more
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CompletedN/A

Treatment Resistant Depression in Bipolar Disorder - A Randomized Controlled Trial of Electroconvulsive Therapy

This project is a randomized controlled trial of electroconvulsive therapy (ECT) compared to treatment as usual (TAU) in the treatment of treatment resistant depression (TRD) in bipolar disorder. The purpose of the trial is to document the

Bergen, Norway+1 more
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CompletedN/A

Treating Depression Among Low-Income Patients With Cancer

The ADAPt-C collaborative depression care model is designed to: improve depression symptom reduction in the intervention group over the modestly enhanced usual care group of low-income, predominantly Hispanic, patients with cancer who are r

Los Angeles, California, United States
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Active, not recruiting

Predictors and Clinical Outcomes of Patients With Coronary Heart Disease Co-morbid Depression Post Percutaneous Coronary Intervention

A prospective, multicenter, registered cohort study to observe the incidence of 1-year major adverse cardiac events in patients with coronary heart disease co-morbid depression treated with percutaneous coronary intervention and to clarify

Nanjing, Jiangsu, China
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By invitationN/A

Positron Emission Tomography in Transcranial Magnetic Stimulation Intervention for Treatment-resistant Depression

Major depressive disorder (MDD) exhibit reduced visual motor perception, which affects prognosis. Metabolic substance changes and abnormal neural activity in the middle temporal visual area (MT) mediate this perceptual dysfunction.

Hangzhou, Zhejiang, China
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CompletedN/A

Social Skills Group Training ("KONTAKT") for Children and Adolescent With High-functioning Autism Spectrum Disorders

This trial investigates the behavioral effects of manualized social skills training (KONTAKT) in children´s and adolescents with high-functioning autism spectrum disorder with psychiatric comorbidity in a RCT, multicenter study. N = 288 are

Stockholm, Sweden
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CompletedN/A

High Pain Intervention in Cesarean Sections

In previous studies the investigators have seen that the severity of pain one day after cesarean delivery can predict the presence of pain and depression 2 months later. The investigators believe those at risk for severe acute post-partum p

Winston-Salem, North Carolina, United States
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CompletedN/A

5-element Music Therapy on Patients With Breast Cancer

In this study, we observed the clinical effect of using music therapy of TCM to improve the status of liver depression in patients with postoperative breast cancer patients, Second we want to explore the efficacy and advantages of tradition

Guangzhou, Guangdong, China
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UnknownN/A

Group Music Therapy for Chinese Prisoners

The prevalence of psychological problems is high in prisons. Many prisoners have unmet needs for appropriate treatments.

Beijing, Beijing Municipality, China
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CompletedPhase 2

RCT of Psychoeducational Program of Depression

The purpose of the study is to test the efficacy of a psychoeducational group program on unipolar depression

Oslo, Norway
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Completed

Post-COVID-19 Epidemic Depression Assessment in Adults in South Punjab Pakistan

To assess the depression in adults especially in post COVID-19 duration in the rural and urban settings.

Chak Four Hundred Fifty-four, Punjab Province, Pakistan+4 more
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CompletedN/A

Neural Mechanisms Underlying the Antidepressant Effects of Sleep Deprivation

From 40 to 60% of patients with depression experience a rapid and significant improvement of mood with one night of sleep deprivation (SD). The neural mechanisms underlying this effect have not been elucidated.

Philadelphia, Pennsylvania, United States
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CompletedN/A

The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Depression

--\> This is a substudy of the main ESTxENDS trial (NCT03589989). Depression outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.

Lausanne, Canton of Vaud, Switzerland+4 more
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CompletedPhase 2 / Phase 3

Transcranial Direct Current Stimulation to Treat Major Depressive Disorder

The investigators purpose is to offer active Transcranial Direct Current Stimulation (tDCS) in patients of the investigators previous study who received either placebo or sertraline and have not responded.

São Paulo, São Paulo, Brazil
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Completed

Dry Eye Under China's Dynamic COVID-zero Strategy

To compare the prevalence of dry eye symptoms and to investigate the association of the risk factors with the dry eye symptomatology among university students in the epidemic and non-epidemic areas of China under the COVID-zero strategy.

Nanchang, Jiangxi, China
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RecruitingN/A

Feasibility of Empowerment Group Therapy on Ukrainian Adult Outpatients

This single-arm pilot study aims to explore the feasibility and acceptability of the culturally adapted, Ukrainian version of the Empowerment Group Therapy (Wiechers, 2023) manual and accompanying workbook for the Ukrainian population affec

Kyiv, Kyiv Oblast, Ukraine
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CompletedPhase 2

The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health

This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in postmenopausal women.

Lake Worth, Florida, United States+4 more
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