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CompletedN/A

Physical Activity Promotion Added to Standard Care Pulmonary Rehabilitation and Cognitive Behavioural Therapy

In patients with Chronic Obstructive Pulmonary Disease (COPD) daily physical activity is reduced compared to healthy age-matched individuals. Reduced levels of physical activity in patients with COPD are associated with increased risk for e

Newcastle upon Tyne, Tyne and Wear, United Kingdom
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CompletedPhase 3

KIDNET vs Meditation/Relaxation - a Dissemination Randomized Controlled Trial for the Treatment of Traumatized Children After War in Sri Lanka

The purpose of this study is to assess the efficacy of KIDNET versus a Meditation/Relaxation protocol in treating traumatized children when applied by locally trained teacher counsellors as well as the effectiveness and adequacy of such a t

Jaffna/Vallikamam, Sri Lanka
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CompletedPhase 3

Exercise Training in ICD Recipients; Effect on Therapy Delivered, Depression and Anxiety

Interventional study in patients with ICD. Controlled, open intervention with exercise training.

Stavanger, Norway
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CompletedPhase 2

A Study of JNJ-55308942 in the Treatment of Bipolar Depression

The purpose of this study is to evaluate the efficacy of JNJ-55308942 compared to placebo on symptoms of depression in participants with bipolar disorder (BD) in a major depressive episode (MDE) at Week 6.

Huntsville, Alabama, United States+43 more
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UnknownN/A

Parent-Delivered Massage in Paediatric Cancer

The purpose of this study is to determine how parents of children with cancer rate a parent-delivered massage therapy educational program for usability and satisfaction, and if massage therapy, provided by parents to their child with cancer

Edmonton, Alberta, Canada+1 more
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WithdrawnN/A

VR Mindfulness Study

This is an exploratory study investigating the use of virtual reality-based guided mindfulness meditation in improving pain, stress, and mood within various clinical populations. The feasibility of utilizing VR applications within the popul

Multiple locations
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Active, not recruitingN/A

TEAMS R34 #3: Team-Based Implementation Strategy for Pediatric Depression Screening

Pediatric depression is a global concern that has fueled efforts for enhanced detection and treatment engagement. While many health systems have implemented components of depression screening protocols, there is limited evidence of effectiv

San Diego, California, United States
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Completed

Stress and Coping in Caregivers of Younger Patients With Cancer

This research trial studies stress and coping in caregivers of younger patients with cancer. Learning how caregivers of children with cancer experience and cope with chronic stress may help to develop effective programs for reducing caregiv

Winston-Salem, North Carolina, United States+1 more
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Completed

Effects of Volatile Anaesthetics on Incidence of Postoperative Depression and Anxiety in Elderly Patients

This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the impact of volatile anaesthetics on the incidence of postoperative depression and anxiety among elderly patients.

Beijing, Beijing Municipality, China
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CompletedN/A

Effect of Cardiac Rehabilitation on Health Status, Emotional Outcomes, and 90-day Readmission Rate Among Cardiac Surgery Patients

this study aims to investigate the effect of the cardiac rehabilitation program on perceived health, status, anxiety, depression, and 90-day readmission rates for post-cardiac surgery patients. The participants in this study will be randoml

Amman, Jordan
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CompletedN/A

Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression

This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for depression. Even with multiple medication trials, 30 - 40% of patients will experience a phar

San Diego, California, United States+2 more
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TerminatedPhase 3

A Long Term Study of ALKS 5461 in the Treatment of Refractory Major Depressive Disorder (MDD)

This study will assess the long-term safety and tolerability of ALKS 5461 as an adjunctive treatment for refractory MDD.

Tucson, Arizona, United States+33 more
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Completed

EVASTRESS Healthy Subjects

The goal of this observational study is to learn the feasibility of using a mobile application "Stressometer" to measure perceived stresss levels several times per day. The study will also explore if the stress scores collected with the app

Évry, France
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RecruitingN/A

Evaluating the Impact AI Avatar-led Mental Health Interventions for Keeping Employees in Work

This study will examine whether an artificial intelligence (AI) avatar-led mental health programme can help employees experiencing symptoms of depression. The programme delivers structured, self-guided psychological support over several sho

London, United Kingdom
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CompletedN/A

A Psychoeducational Program "BalancingMySwing" for Patients With Bipolar Disorder

The psychoeducation BalancingMySwing (BMS) program has been developed manually and its feasibility has been tested in our previous study. This 3-year research project aimed to further examine the immediate and lasted effects of BMS program

Multiple locations
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UnknownN/A

Reducing Depressive Symptoms During HCV Therapy: A Randomized Study

The purpose of this study is to conduct a randomized controlled trial of an 8-visit non-pharmacologic group intervention in reducing the severity of depressive symptoms in veterans who receive IFN and ribavirin for the treatment of Hepatiti

San Antonio, Texas, United States
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TerminatedPhase 2

Quetiapine in Postpartum Depression

The purpose of the study is to evaluate the efficacy and tolerability of quetiapine in female patients with postpartum depressive disorder with psychotic symptoms

Herten, Westfalen-Lippe, Germany
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WithdrawnPhase 2

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Treatment Resistant MDD

This open-label fMRI study will assess the effects of a single dose of psilocybin on rumination and the neural correlates of rumination in individuals with treatment-resistant major depressive disorder.

Charlestown, Massachusetts, United States
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Not yet recruitingN/A

Ketogenic Diet and Neuromodulation in Treatment Resistant Depression

The goal of this clinical trial is to learn if combining a ketogenic diet with a personalized, accelerated brain stimulation treatment (iTBS) works better than iTBS with a standard healthy diet to reduce depression symptoms in adults with t

Toronto, Ontario, Canada
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CompletedN/A

A Transdiagnostic Sleep and Circadian Treatment for Depression

This study will examine the use of a transdiagnostic Sleep and Circadian Treatment (TranS-C) in treating Major Depressive Disorder (MDD) in Chinese adults. Sleep disturbance is highly comorbid with a range of psychological disorders, especi

Hong Kong, Hong Kong
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