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UnknownN/A

Psychoeducation Versus Cognitive-Behavioral Therapy in Bipolar Disorder

To examine the impact of cognitive-behavioural therapy on both the episodic and functional outcome of bipolar disorder, in combination with pharmacotherapy. Primary Hypothesis is twofold: 1.

Vancouver, British Columbia, Canada+5 more
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Unknown

DRACULA1 Partum Depression: an Integrated Molecular-pharmaco-imaging Study")

Post-partum depression (PPD) is a prevalent subtype of major depressive disorder that causes a significant distress to the woman and substantial impact on the whole family. Many studies implicate the glutamatergic system in pathological pro

Milan, MI, Italy
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CompletedPhase 4

Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication

This study will examine how brain activity is affected by antidepressant treatment and how changes in brain activity relate to treatment response in people with depression.

Los Angeles, California, United States+2 more
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CompletedN/A

Effects of a 10-Week Zumba Program on Anxiety and Depression in Adults

This randomized controlled trial aimed to examine the effects of a 10-week Zumba exercise program on anxiety and depression levels in healthy adults. Participants aged 40 to 65 years were randomly assigned to either a Zumba intervention gro

Osuna, Sevilla, Spain
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Not yet recruitingPhase 2

Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial-

Depression in neurocognitive disorders (Alzheimers' disease and related disoders) is a highly prevalent condition, especially in nursing homes. While it is associated with significant distress, the current conventional antidepressants have

Multiple locations
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UnknownPhase 1

Impact of Lucentis on Psychological Morbidity in Patients With Retinal Vein Occlusion

This is a prospective, single-center, non-randomized clinical study on the impact of intravitreally administered ranibizumab (Lucentis) treatment on vision-related functioning and emotional well-being in subjects with central or branch reti

Cleveland, Ohio, United States
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CompletedEARLY_Phase 1

Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine

The overarching aim of this research is to determine the acute effects of ketamine on brain glutamate, functional connectivity and cerebral blood flow in treatment-resistant depression, explore whether the effects are attenuated by the opio

London, United Kingdom
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CompletedN/A

Environmental Treatment for Seasonal Affective Disorder (SAD)

The purpose is to study treatments of Seasonal Affective Disorder (SAD).

New Haven, Connecticut, United States+4 more
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Completed

Combination Deplin® and Antidepressant Therapy for a Major Depressive Episode (MDE)- a Retrospective Analysis

This is a retrospective chart review study to determine if Deplin® 7.5mg-15mg combined with an antidepressant is better than an antidepressant alone in adults with major depression.

Houston, Texas, United States
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UnknownN/A

Use of tDCS Applied to the Orbitofrontal Cortex to Improve Risky Decision-making in a Clinical Population

Decision-making is a complex cognitive function that has been the subject of extensive scientific research in the fields of cognitive and computational neuroscience. It relies on a cerebral network that encompasses cortico-subcortical pathw

Paris, France
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RecruitingN/A

Therapist-Guided Internet-Delivered CBT for Chronic Conditions: Predictors of Change

Chronic health conditions are common, disabling, and often co-occur with depression and anxiety. Internet-delivered cognitive behaviour therapy (ICBT) reduces barriers to treatment and has been adapted for chronic conditions.

Regina, Saskatchewan, Canada+1 more
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CompletedN/A

Trial of the Youth Readiness Intervention

The research will first examine data obtained from YRI participants to investigate effects of the group sessions on psychosocial and functioning outcomes in youth. In pursuit of this aim, this research will investigate the following hypothe

Freetown, Sierra Leone
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RecruitingN/A

Transcranial Direct Current Stimulation for Depression

Several studies have shown that tDCS is valuable and safe options to improve depressive symptoms in adult patients . However, regarding the tDCS to treat depression in elderly population, only few studies have been reported, and there is no

Taipei, Taiwan
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Completed

Intravenous Iron May Increase Depression Among Hemodialysis Patients

the aim of this study is to assess whether increased ferritin after intravenous iron therapy will lead to increased prevalence of major depression among treated patients.

Multiple locations
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RecruitingN/A

Effect of Exercise on Tapering Antipsychotics in Patients With Psycho-cardiological Disease(EXTRA-study)

Psycho-Cardiological Disease studies the complex links between the cardiovascular system and emotions. The two diseases are now the focus of public health organizations, forming a vicious circle of mutual influence.

Guangzhou, Guangdong, China
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Completed

Psychiatric Manifestations Associated With Behcet's Disease

The psychoBehçet'study is aimed at evaluating the psychological and neurocognitive symptoms in 25 consecutive patients followed for Behçet's disease. This is a monocentric, observational, non interventional study.

Le Kremlin-Bicêtre, Val de Marne, France
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By invitation

Blood Biomarkers in Electroconvulsive Therapy

The present multi-disciplinary study will assess blood biomarkers to investigate putative mechanisms of action of ECT. Laboratory findings will be correlated to clinical parameters, cognitive measures and psychometric outcome measures.

Bergen, Norway
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Completed

Physical Exercise, Motor Activity and Depression in Post-mastectomy Pain Syndrome

Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli.

Messina, Italy
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Completed

Testosterone and Major Depression

Context - As men age, testosterone levels decline leading to symptoms that overlap with the symptoms of major depression. Little is known about the potential role of testosterone in the treatment of major depression.Objective - To assess th

Toronto, Ontario, Canada
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UnknownPhase 4

Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study

The purpose of the study is to examine the connection between the dose of paroxetine and the effect of paroxetine on tramadols metabolism and thereby the effect of tramadol on the median pupil size. In the study 12 healthy volunteers are go

Multiple locations
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