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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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CompletedN/A

Psychophysiological Effects of Birdsongs VS Music

The main goal of this study is to learn the psychophysiological effects of birdsongs on sadness. The main questions it aims to answer are: 1.

Hangzhou, Zhejiang, ChinaView details
RecruitingN/A

A Study of Home-use Brain Stimulation to Treat Bipolar Depression

Bipolar depression is a long-lasting and disabling condition, and many people continue to experience depressive symptoms despite standard treatments. Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation

London, United KingdomView details
Unknown

Implementation of Brief Dynamic Interpersonal Therapy at the VA

The goal of the proposed project is to collect data from clinician files and the electronic medical record to describe the clinical implementation of Brief Dynamic Interpersonal Therapy (DIT), an individual psychotherapy for depression and

New York, New York, United StatesView details
CompletedN/A

Effect of Ketamine in Depressive Symptoms of Elderly Patients With Visual Impairment.

the prevalence of depression in elderly is from 4 to 30% and is associated with a lower quality of life mayor medical comorbidity, and increased mortality. Although there are various treatments for depression in the elderly, the study of in

Mexico City, Mexico City, MexicoView details
Active, not recruitingN/A

Open Label - Personalized Therapeutic Neuromodulation for Anhedonic Depression

This study will investigate the anti-anhedonic efficacy of a novel neurostimulation strategy termed accelerated intermittent theta burst stimulation (aiTBS) in participants with treatment resistant depression (TRD).

Stanford, California, United StatesView details
RecruitingPhase 1

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-establishe

Kansas City, Kansas, United States+1 moreView details
Not yet recruitingN/A

Functional Magnetic Resonance Imaging Study of Inhibitory Control in Bipolar Disorder and Major Depressive Disorder

Bipolar disorder and unipolar depressive disorder are two chronic mood disorders associated with a significant social impact, even during euthymic phases. Their differential diagnosis remains complex, particularly when bipolar disorder begi

Reims, FranceView details
Terminated

Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel

Depression and bipolar disorder are major public health concerns for adolescents today. Teenage depression and bipolar disorder are associated with social isolation, family stress, school failure, substance abuse and suicide.

Salt Lake City, Utah, United StatesView details
WithdrawnPhase 2

Trial of Ketamine and Lithium Therapy in Bipolar Depression

This study is looking at the safety and efficacy of combined ketamine and lithium therapy for treating patients with bipolar depression who are taking a mood stabilizer that is not working for them.

Multiple locationsView details
Completed

Badalona Major Depressive Disorder Database Study

A retrospective study using a data base of anonymized medical records. The purpose of the study is to examine the different therapeutic strategies for the management of patients with major depressive disorder (MDD) and suboptimal response t

Badalona, SpainView details
RecruitingN/A

Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults

In this study, the investigators will be examining the effects of the deep repetitive transcranial magnetic stimulation (rTMS) using the H1 coil in patients over the age of 60 diagnosed with mild to early-moderate Alzheimer's disease (AD) o

Toronto, Ontario, CanadaView details
CompletedN/A

Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease

This is a randomized, single-blinded, triple crossover study focused on determining the feasibility of using transcranial magnetic stimulation (TMS) for treatment of Parkinson's disease related autonomic dysfunction and depression. Particip

Chapel Hill, North Carolina, United StatesView details
CompletedN/A

Does a Novel Intervention Targeting Derailment Decrease Depressive Symptoms?

The goal of this clinical trial is to explore the efficacy of a reflective journaling intervention-"Me Through Time"- in decreasing levels of derailment, and its impact on downstream depressive symptoms.

Ithaca, New York, United StatesView details
CompletedPhase 2 / Phase 3

Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffering Capacity

The aim of our study was to evaluate the clinical efficacy of a topical sialogogue spray containing 1% malic acid on patients affected by xerostomia caused by drugs. This research took the form of a double-blind, randomized clinical trial a

Granada, Granada, SpainView details
Unknown

COVID-Impact "Psychological IMPACT of Covid-19 on AP-HP Staff"

The epidemic of coronavirus induces a major influx of patients implying a rapid modification of the organizations, a work overload and a significant stress for the care teams and supports of the hospitals of the Assistance Publique - Hôpita

Paris, Île-de-France Region, FranceView details
Unknown

The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia

Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors. There is also increased incidence of depression and anxiety

Multiple locationsView details
CompletedN/A

Genecept Assay™ vs. Treatment-as-Usual to Evaluate Efficacy of Assay-Guided Treatment in Adults With MDD

In this randomized clinical trial, subjects will be assigned to either an assay-guided treatment condition (AGT) or a treatment-as-usual condition (TAU). All subjects will provide a DNA sample at the Screening Visit for the Genecept Assay ™

Birmingham, Alabama, United States+22 moreView details
CompletedN/A

Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures

This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing cardiac surgery (compared wit

St Louis, Missouri, United StatesView details
CompletedN/A

Social Media, Teen Moms and PPD

Approximately 400,000 live births occur to adolescents in the United States annually. Of the 50% of adolescent mothers who experience depressive symptoms, less than 25% comply with referrals for depression evaluation and treatment due to la

Carrollton, Kentucky, United States+7 moreView details
Not yet recruitingN/A

Efficacy and Safety of Transcranial Alternating Current Stimulation (tACS) Combined With Stable Medication in Adolescents With Depression: A Randomized, Double-Blind, Controlled Pilot Study

To evaluate the efficacy of tACS treatment. To determine whether tACS can accelerate symptom remission, improve clinical response rates, and facilitate the recovery of emotional and cognitive functions through standardized clinical assessme

Chongqing, Chongqing Municipality, ChinaView details
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