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Completed

Latinx Teen Depression Treatment Study

The purpose of this study is determine facilitators of and barriers to receiving evidence-based psychotherapy for depression for Latinx adolescents from multiple stakeholder perspectives.

Durham, North Carolina, United StatesView details
UnknownPhase 4

Clozapine Versus Olanzapine as Treatment for Comorbid Psychotic Disorder and Substance Use Disorder

The purpose of this trial is to determine if patients with comorbid psychotic disorder and substance use disorder will continue in treatment longer if treated with clozapine than with olanzapine, and will have greater reductions in psychosi

Evans, Georgia, United StatesView details
Completed

Noninvasive Physiologic Sensors to Assess Depression

This project aims to use sensors to monitor physiological signals, sleep patterns, vocal characteristics, activity, location and phone usage in study patients with depression who are receiving standard treatment (compared with healthy contr

Boston, Massachusetts, United StatesView details
CompletedN/A

Treatment Outcomes and Predictive Factors of the Effectiveness and Adherence of Moodpep: an Online Self-help Intervention for College Students With Depressive Symptoms

Depressive symptoms are prevalent among college students and often remain untreated. E-health interventions may help overcome treatment barriers by offering accessible and flexible support.

Amsterdam, Netherlands+1 moreView details
CompletedN/A

Effectiveness of Internet-Based Cognitive Behavioral Therapy for Treating Mothers With Depression

This study will evaluate the effectiveness of an Internet-based cognitive behavioral therapy program in treating mothers with depression who have young children.

Eugene, Oregon, United StatesView details
Recruiting

Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project

The purpose of this research study is to characterize the mechanisms contributing to cognitive impairment and accelerated cognitive decline in Late Life Depression (LLD). This is a non-randomized, observational, non-treatment study that ori

San Francisco, California, United States+1 moreView details
CompletedN/A

Predictors of Treatment Outcome With Cognitive Behavioral Therapy for Depression

The purpose of this research study is to learn whether specific types of brain imaging and psychological testing can predict how much benefit patients with depression will receive from a well-studied psychotherapy for depression, called cog

New York, New York, United StatesView details
CompletedN/A

Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People With SMI

People who have a severe mental illness can have poorer physical health and higher mortality rates than the general population. Their medications combined with low levels of physical activity and increased sedentary behaviour can general po

Dundalk, Louth, Ireland+2 moreView details
CompletedN/A

The Effect of Progressive Muscle Relaxation Exercises

Purpose This study was carried out to examine the effectiveness of Progressive Muscle Relaxation (PMR) exercises on mothers' breastfeeding self-efficacy and depression level with preterm infants. Methods This study was conducted in a random

Istanbul, Şişli, Turkey (Türkiye)View details
Completed

Menopause Age and Anxiety-Depression

Menopause is defined as the permanent cessation of menstrual cycles due to ovarian follicle depletion, typically occurring after age 50, and is associated with decreased estrogen levels. Primary ovarian insufficiency (POI) involves early ov

Ankara, Not Valid, Turkey (Türkiye)View details
CompletedPhase 2

Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine System

This study will assess the helpfulness of the integrated call center in optimizing use of the Digital Medicine System in adult subjects with Schizophrenia, Major Depressive Disorder, or Bipolar Disorder taking oral aripiprazole.

Granada Hills, California, United States+3 moreView details
CompletedPhase 3

Sertraline for the Prevention of Recurrent Postpartum Depression

This study will determine the effectiveness of taking sertraline within 24 hours of giving birth in preventing a recurrence of postpartum depression.

Pittsburgh, Pennsylvania, United StatesView details
CompletedN/A

Equity Using Interventions for Pain and Depression - Pilot Study

This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This pilot randomized controlled trial (RCT) is part of phase 1 of a two-phase, 5-year project with the overarching goal of testin

Indianapolis, Indiana, United StatesView details
CompletedN/A

Impact of a Communication Strategy in the Prevention of Depressive Symptoms in Patients with Covid-19

The purpose of this study is to compare the effect of an early and integral communication strategy (EICS) versus standard care, on the rate of depressive symptoms at 3 months after discharge from the ICU, in patients with severe Covid-19, t

Santiago, Santiago Metropolitan, ChileView details
Completed

Somatic Symptoms and Depression in Undergraduate Physiotherapy Students: A Community-Based Cross-Sectional Study

This cross-sectional, community-based study aimed to investigate the association between depression and somatic symptoms among physical therapy students in Egypt. Using validated tools-the PHQ-9 for depression and PHQ-15 for somatic symptom

Giza, EgyptView details
TerminatedN/A

Pulmonary Rehabilitation in Functional Outcomes and Its Relationship With Morbidity and Mortality in Patients With COPD

Background: The pulmonary rehabilitation effects on various outcomes of COPD are well known. However, they may be lost over time due to poor adherence to therapy with absence of regular exercise maintenance in long term, disease progression

Florianópolis, Santa Catarina, BrazilView details
CompletedN/A

Universal Screening for Maternal Depression With the CHICA System

The CHICA system is a clinical decision support system that uses adaptive turnaround documents to provide point-of-care information to clinicians. We will be studying whether it can help in the diagnosis and referral of mothers with materna

Indianapolis, Indiana, United StatesView details
UnknownPhase 2

Antidepressant Trial With P2X7 Antagonist JNJ-54175446

Depression is one of the most important causes of disability in the world today, with major personal, social and economic costs. Although some moderately effective drug treatments are already available, about a third of patients with major

Cambridge, Cambridgeshire, United Kingdom+4 moreView details
WithdrawnN/A

Supplemental Transcranial Magnetic Stimulation (TMS) vs. Standard Medication Monotherapy for Treating Major Depression: An Exploratory Field Study

A. Introduction to the Problem This field experiment is intended to explore whether supplemental transcranial magnetic stimulation (TMS) is more effective than standard medication mono-therapy for the treatment of major depressive disorder

Towson, Maryland, United StatesView details
Not yet recruitingN/A

A Virtual Peer Agent for Counseling Adolescents With Stressful Life Events

This study aims to develop and evaluate a virtual companion agent for providing psychological support to adolescents who have recently experienced stressful life events. This is a single-arm, pre-post pilot trial.

Multiple locationsView details
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