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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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Cognitive Impairment and Affective Mood Disorders in Patients With IBD

The aim is to evaluate the presence of mild cognitive impairment (MCI) in patients with inflammatory bowel disease (IBD). This will be done by cognitive tests.

Cluj-Napoca, Cluj, Romania+2 moreView details
CompletedPhase 2

A Safety and Effectiveness Study of JNJ-18038683 in Patients With Moderate to Severe Depression

The purpose of this study is to evaluate the safety and effectiveness of JNJ-18038683 compared to escitalopram and placebo in patients with moderate to severe depression.

Little Rock, Arkansas, United States+25 moreView details
CompletedN/A

Mobile Mindfulness to Improve Psychological Distress After Critical Illness

Many survivors of the intensive care unit (ICU) suffer from persistent symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD). In this study, the investigators will test the impact of mindfulness to address this distress

Durham, North Carolina, United States+1 moreView details
Not yet recruitingN/A

Impact of Medication Education on Adherence and Side Effects

Severe mental disorders such as schizophrenia, bipolar disorder, and psychotic depression often require long-term or lifelong medication treatment. However, many psychiatric patients have difficulty adhering to their prescribed medication r

Multiple locationsView details
CompletedN/A

Validation of the French Version of the Pain Sensitivity Questionnaire

The Pain Sensitivity Questionnaire (PSQ) is a tool created in 2009 by Dr. R.

Clermont-Ferrand, FranceView details
CompletedN/A

Feasibility and Acceptability of an Educational Intervention to Improve the Management of Depression in Primary Care.

Qualitative study based on interviews and questionnaires with patients participating to an educational intervention to improve the management of depression in primary care. Objective is to assess feasibility and acceptability of an educatio

Marseille, FranceView details
UnknownN/A

Emotion-centered Problem-solving Intervention for Family Caregivers of Stroke Survivors (SoLVE)

Stroke is one of the leading causes of disability globally. Stroke survivors generally require lifelong support from family caregivers.

Hong Kong, Please Select, ChinaView details
UnknownN/A

Infiltrations of OnaBotulinum Toxin A in Resistant Depression: Comparison of Two Facial Injection Sites.

The aim of the study is to evaluate in adult subjects with resistant depression the effect of an injection of botulinum toxin in the corrugator and procerus muscles, in comparison to the infiltration of the crow's feet area, in addition to

Limoges, FranceView details
UnknownN/A

Application of Physical Activity Counseling Program

Abstract Implementation of Physical Activity Counseling Program in Healthy Adult Individuals It was planned to investigate the effects of physical activity counseling on physical fitness level, physical activity level, depression level, sle

Istanbul, Turkey (Türkiye)View details
UnknownN/A

Healthy Bellies - Intervention Program During Pregnancy on Women and Newborn

"Healthy Bellies" is an intervention program with pregnant women, based on the promotion of healthy lifestyles. It aims to evaluate the impact of the program in the health of both pregnant and newborn.

Braga, PortugalView details
CompletedPhase 4

Does Risperidone Consta Reduce Relapse and Rehospitalization in Bipolar Disorder?

This study will evaluate the relative effectiveness of risperidone Consta injections occurring every 2 weeks in contrast to treatment as usual in preventing symptomatic relapse and rates of rehospitalization or admission into respite care f

Nashville, Tennessee, United StatesView details
CompletedPhase 2

Scopolamine in Bipolar Depression

This is a single-site, randomised, double-blind, placebo-controlled, parallel, phase IIb clinical trial. The primary objective of the SCOPE-BD study is to investigate the efficacy and safety of IV Scopolamine, compared to placebo, in reduci

Galway, County Galway, IrelandView details
UnknownPhase 4

Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers

Rationale: Opioid misuse and abuse are common problems in the Western world. The rate of unintentional drug overdose is rapidly increasing, not only in the Unites States but also in the Netherlands.

Leiden, South Holland, NetherlandsView details
Completed

Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy

The goal of this observational study is to measure the levels of cytokine-induced transcription factor activation in a cohort of depressed inpatients undergoing psychotherapy. The study aims to answer the following main questions: * Do psy

Multiple locationsView details
UnknownN/A

Effects of Digitally Delivered and Group-based CBT-I in Pregnant Women With Comorbid Insomnia and Depression

Major depressive disorder (MDD) is a debilitating and recurrent illness associated with a constellation of grave consequences and is among the most common psychiatric disorders during the pregnancy and postpartum periods. Meanwhile, sleep d

Hong Kong, Hong KongView details
CompletedPhase 3

Ethyl Eicosapentanoic Acid (Ethyl-EPA) for Treating Major Depression

The purpose of this study is to examine the effectiveness of ethyl-eicosapentanoic acid (ethyl-EPA), an omega-3 fatty acid, in treating depression.

Boston, Massachusetts, United StatesView details
Not yet recruitingN/A

Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico

Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.

Colima, MexicoView details
CompletedN/A

Repetitive Transcranial Magnetic Stimulation for Adolescent Depression: Efficacy, Predictive Biomarkers, and Mechanisms

This study will be an open-label 6-week (30 session) trial of active repetitive transcranial magnetic stimulation (rTMS) using a fixed frequency (10 Hz) but varying stimulation intensities using a 3+3 study design for safety and tolerabilit

Minneapolis, Minnesota, United StatesView details
RecruitingN/A

The Impact of Melatonin Lotion on Sleep and Mental Health

The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health. Melatonin is a hormone secreted by the brain that regulates sleep and might improve depression and anxiety

Redlands, California, United StatesView details
RecruitingN/A

7T Amygdala and Citalopram Study

The goal of this study is to investigate how a common antidepressant citalopram (which increases the levels of the chemical messenger serotonin), affects how a key area of the brain involved in depression (the amygdala) responds to emotiona

Oxford, Oxfordshire, United KingdomView details
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