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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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CompletedN/A

Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression

The goal of this clinical trial is to evaluate whether magnesium supplementation can improve cognitive function in patients with depression receiving fluoxetine therapy. It also aims to assess its effect on serum brain-derived neurotrophic

Makassar, South Sulawesi, IndonesiaView details
Active, not recruiting

Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 (PASC) Using TSPO Positron Emission Tomography (PET) and MRI

The overarching goal of this study is to develop PET/MR techniques for the diagnosis of neuropsychiatric post-acute sequelae (PASC) of SARS-CoV-2. The central hypothesis is that immunological and cerebrovascular dysfunction after acute SARS

New York, New York, United StatesView details
CompletedPhase 1

Polarity Therapy for American Indian Caregivers of Dementia Patients

The purpose of this study is to assess the effectiveness of polarity therapy (PT), a complementary and alternative medicine treatment, in American Indian caregivers living in the Pacific Northwest.

Olympia, Washington, United StatesView details
Recruiting

LHC-CIDI-5 in Hong Kong

The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and

Hong Kong, Hong KongView details
Completed

HRQoL in the Low MELD Pre-tx Population

The purpose of this study is to describe the HRQoL in those with MELD scores \</= 15 in a single center for those who are pre-liver transplant candidates

Multiple locationsView details
CompletedN/A

Habits of Gamers Study

Rationale: Mindfulness is a popular therapeutic strategy that has a growing body of evidence suggesting it can improve a wide range of physical and psychological symptoms. Yet, confusion exists as to why mindfulness is effective as well as

Los Angeles, California, United StatesView details
Active, not recruitingN/A

Integrated Mental Healthcare Plan for Management of Depression and Self-harm in Pakistan

Aims: 1. To describe the process of developing a feasible district mental healthcare plan (MHCP) for depression, self-harm and suicide prevention, and 2.

Thatta, Sindh, PakistanView details
CompletedPhase 3

Use of N-Acetylcysteine (NAC) in Fingernail Biting

To conduct a pilot randomized placebo-controlled feasibility trial of N-acetylcysteine (NAC) in onychophagia, preliminarily assessing the tolerability and effects of this pharmacotherapy on young adults who bite their fingernails. It is pro

Charleston, South Carolina, United StatesView details
RecruitingN/A

Cold and Heat Investigation to Lower Levels of Depression

This study will recruit 112 medically healthy adults (aged 18-65) currently experiencing depressive symptoms to be randomized to receive either a single Whole Body Hyperthermia (heat therapy) treatment or a Whole Body Hyperthermia treatment

Edwards, Colorado, United StatesView details
Completed

Neuromodulation to Facilitate the Effect of Ketamine

application of external neuromodulation along with ketamine infusion.

Deerfield, Illinois, United StatesView details
Unknown

What Are the Effects of Varenicline Compared With Nicotine Replacement Therapy on Long Term Smoking Cessation and Clinically Important Outcomes?

Introduction: Smoking is a major avoidable cause of ill-health and premature death. Treatments that help patients successfully quit smoking have an important effect on health and life expectancy.

Multiple locationsView details
WithdrawnN/A

The Impact of Mindfulness Meditation in Veterans With Epilepsy

Epilepsy is one of the fourth most common neurological disorder and affects people of all ages and about 25 % of those patients have medically intractable epilepsy. Since the traditional pharmaceutical and surgical approach is not always ef

Miami, Florida, United StatesView details
Terminated

Impact of a Mental Health Support Program on of Medical Residents' Stigmatization Towards People With Lived Experience

The program, called the Mental Health Practice Support Program, is designed to teach new tools and skills for working with patients with mental health concerns in a family practice setting. The program is also being evaluated for effectiven

Halifax, Nova Scotia, CanadaView details
CompletedN/A

Preventing Insomnia With Virtual Oneshot Therapy (PIVOT)

This study is intended to assess the efficacy of preventative Cognitive Behavioral Therapy for Insomnia (pCBT-I) on reducing the severity and stopping the progression of acute insomnia and depression. We also hope to gain a deeper understan

Novi, Michigan, United StatesView details
CompletedN/A

Indicated Prevention Transdiagnostic Intervention for Adolescents At High Risk of Emotional Problems

Emotional disorders (anxiety and/or depression) are severely undiagnosed and untreated despite being among the most common mental disorders, particularly at a young age. Half of all mental disorders begin by age 14; three-quarters by age 24

Elche, Alicante, Spain+2 moreView details
UnknownN/A

Remote Supervision for Implementing Collaborative Care for Perinatal Depression

This study evaluates the impact of a longitudinal remote consultation (LRC) implementation strategy for collaborative care depression treatment among perinatal women. All participating health centers will receive training in collaborative c

Seattle, Washington, United StatesView details
Not yet recruitingN/A

Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial

Transcranial magnetic stimulation(TMS) is a non-invasive form of brain stimulation that is cleared by the United States Food and Drug Administration (FDA) for depression. Conventional TMS involves daily weekday treatments for 6-8 weeks.

Multiple locationsView details
CompletedN/A

HOPE Pilot for Veterans With Complex Diabetes

The purpose of this study is to determine if behavioral health coaching for rural veterans with diabetes and depression will improve self-management behaviors and lead to improvement in diabetes care outcomes (e.g., HA1C) and improvement in

Houston, Texas, United StatesView details
CompletedPhase 3

The Use of Galantamine HBr (Reminyl) in Electroconvulsive Therapy: Impact on Mood and Cognitive Functioning

The purpose of the study is to see if galantamine HBr (Razadyne) is safe and can help treat problems with thinking and memory caused by electroconvulsive therapy (ECT).

Boston, Massachusetts, United StatesView details
CompletedPhase 3

Escitalopram in Adult Patients With Major Depressive Disorder

This is a short-term study to evaluate the efficacy, safety, and tolerability of escitalopram in adult patients (18 to 65 years of age) with moderate to severe depression. Patients completing the study may be eligible to enter a long-term o

Phoenix, Arizona, United States+44 moreView details
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