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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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CompletedN/A

Impact of Massage Therapy on the Quality of Life of Hospice Patients

This is a pilot study to evaluate the impact of massage therapy in hospice patients.

Rochester, Minnesota, United StatesView details
CompletedN/A

Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient Smokers

This study will assess whether varenicline (chantix) has antidepressant properties when used in addition to other psychiatric medication. It will also assess whether varenicline improves the inability to feel pleasure (i.e.

Providence, Rhode Island, United StatesView details
TerminatedN/A

Pharmacogenetic and Antidepressant Treatment in Elderly

The study aims to assess the therapeutic benefits of the adaptation of the antidepressant dose to the metabolic capacity (cytochrome P450 2D6) of elderly depressed patients. Therapeutic benefits are evaluated through the enhancement of effi

Besançon, Doubs, FranceView details
CompletedN/A

Depressed Adolescents Treated With Exercise (The DATE Study)

This study will evaluate whether standardized aerobic exercise is an effective treatment for depression in adolescents.

Multiple locationsView details
CompletedPhase 2

Reclaim Deep Brain Stimulation Clinical Study for Treatment-Resistant Depression

Medtronic, Inc. sponsored an investigational study of the Reclaim™ Deep Brain Stimulation (DBS) System in people that have treatment-resistant depression.

Charlestown, Massachusetts, United States+4 moreView details
Completed

Impact of Oral Versus Intravenous 5-FU-Based Adjuvant Regimens on Sleep Quality and Depression in Patients With Gastrointestinal Cancers

This prospective, non-randomized, single-center observational study is designed to investigate the effects of oral versus intravenous (IV) 5-fluorouracil (5-FU)-based adjuvant chemotherapy regimens on sleep quality and depression levels in

Ankara, Yenimahalle, Turkey (Türkiye)+2 moreView details
Completed

Intracranial Atherosclerosis and Depression After Coronary Artery Bypass Graft

The purpose of the study is to examine if blood flow in the brain before coronary artery bypass graft surgery has an effect on depression after surgery. The main hypothesis of the study states that pre-surgical blood flow in the brain will

New Haven, Connecticut, United States+1 moreView details
CompletedN/A

Building Resilience in Cyberbullying Victims

This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims. Half of the participants will receive the experimental intervention, whi

Bilbao, Bizkaia, SpainView details
TerminatedPhase 2

Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer

Depression is common in patients with cancer. Current medications for depression, while effective, take several weeks to take effect.

Scottsdale, Arizona, United States+1 moreView details
CompletedN/A

The RAFT ECT Study

Severe depression is devastating for those affected and is often associated with significant risk of suicide. Electroconvulsive therapy (ECT) is a highly effective acute treatment for severe depression, but its use and acceptability are lim

Atlanta, Georgia, United States+6 moreView details
CompletedN/A

MoodUP in Improving Psychological Outcomes Among Perinatal Women

Dramatic physiological, psychological, and social changes during the antenatal period may significantly affect a woman's psychosocial and physical conditions, thereby resulting in stress, anxiety, and depressive symptoms. Cognitive behavior

Singapore, SingaporeView details
CompletedN/A

Sleep to Prevent Evolving Affecting Disorders

The primary objective of the proposed research is to determine the efficacy of Digital Cognitive Behavior Therapy (dCBTI) in reducing severity of depression and also in preventing the incidence and relapse of depression among insomniacs. In

Detroit, Michigan, United StatesView details
Unknown

Hypertension and Diabetes Assessment in the Rohingya Refugee Population and in the Host Communities in Bangladesh

Due to a massive outbreak of violence against the Rohingya minority residing in the Rakhine State of Myanmar in late 2017, several hundred thousand Rohingya fled the country and sought a shelter in Bangladesh. Currently, in the refugee sett

Multiple locationsView details
CompletedN/A

Improving Physical and Psychosocial Well-being of African American Older Adults

The proposed research effort will: The purpose of this study is as follows: 1. Test the feasibility and acceptability of an eight-week community-based exercise program among AA older adults living in rural areas.

Uniontown, Alabama, United StatesView details
Active, not recruitingN/A

NYUCI-ES: Psychosocial Intervention to Improve Health Outcomes for Chinese and Korean ADRD Caregivers

This study will conduct a two-arm randomized controlled trial to test the efficacy of a culturally tailored version of the NYU Caregiver Intervention (NYUCI) plus enhanced support (ES) through online chat groups (the NYUCI plus WeChat/Kakao

New York, New York, United StatesView details
TerminatedPhase 2 / Phase 3

EScitalopram PIndolol ONset of Action

The main purpose of this study is to determine whether the antidepressant response of escitalopram 30mg/day or escitalopram 20mg/day + pindolol, a beta blocker, is different (faster) compared to a standard dose of escitalopram 20mg/day.

Geneva, SwitzerlandView details
Not yet recruitingN/A

Using Virtual Reality Technology on Depression, Anxiety, and Stress Among Palestinian Patients Undergoing Breast Biopsy

The goal of this randomized controlled trial was to investigate the impact of Virtual Reality (VR) technology on depression, anxiety, and stress levels among Palestinian patients undergoing breast biopsy. The study aimed to evaluate the eff

Multiple locationsView details
Active, not recruitingPhase 1

Depression Treatment and Screening in Ovarian Cancer Patients

The goal of this behavioral research study is to find a quick and effective way to identify depression in patients with ovarian, peritoneal, or fallopian tube cancer. Another goal of this study is to compare an intervention program with "en

Houston, Texas, United StatesView details
CompletedN/A

Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder

Acupoints are the stimulus points and reactive points for acupuncture to treat diseases. Therefore, this study is designed to detect the pain threshold and temperature of biological specificities of acupoints in healthy control (HC) partici

Hangzhou, Zhejiang, ChinaView details
WithdrawnN/A

Repetitive Transcranial Magnetic Stimulation as Therapy for Depression in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of central and peripheral motor neurons. ALS leads to death usually within 3 to 5 years from the onset of the symptoms.

Krakow, PolandView details
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