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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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UnknownN/A

Mobile Application in the Management of Mild to Moderate Postpartum Depression (PPD)

Primary Objective: Evaluate the user experience with the Stella (TM) app for the management of Postpartum Depression in an observed population for 8 calendar weeks.

New York, New York, United StatesView details
CompletedN/A

Initiating and Maintaining Physical Activity in Depressed Individuals

The investigators propose a randomized clinical trial in which 240 depressed individuals are assigned to one of three arms, with each successive arm having an added component that may serve to increase and maintain physical activity: 1. br

Providence, Rhode Island, United StatesView details
TerminatedPhase 3

SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study

This study is an optional continuation of previous short-term adult major depressive disorder (MDD) augmentation studies. Patients may only take part in this long-term, open-label research study if they completed a previous double-blind MDD

Birmingham, Alabama, United States+211 moreView details
WithdrawnN/A

Mood and Anti-craving Effects of Varenicline in Psychiatric Inpatients

This study of psychiatric inpatients will assess mood effects of varenicline, as well as assess if varenicline decreased nicotine cravings acutely. This study will also measure side effects of varenicline when given in addition to other psy

Providence, Rhode Island, United StatesView details
UnknownN/A

EEG Objectification in Neuropsychiatry

The main objective of the study is to evaluate the use of EEG in the management and follow-up of neuropsychiatric disorders. Secondary objectives are therefore better understanding of the pathological activations in neural network during ne

Jerusalem, IsraelView details
RecruitingPhase 3

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

X-NOVA3 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants diagnosed with Major Depressive Disorder

Dothan, Alabama, United States+41 moreView details
RecruitingN/A

CALM Study: Can A Prebiotic Fibre bLend Improve Stress, Mood, and Anxiety?

This clinical trial will investigate whether a powdered prebiotic fibre blend can improve perceived stress levels in healthy adults with mild-severe stress levels.

London, United KingdomView details
UnknownPhase 4

Antidepressants During Pregnancy and Lactation: Pharmacokinetics and Clinical Implications

Background: The childbearing years are a time of increased vulnerability to the onset of mood disorders in women and a high prevalence of exposure to antidepressant drugs during pregnancy and postpartum has been reported. However, the lack

Nancy, Meurthe-et-Moselle, France+4 moreView details
Completed

Adolescent Mental Health: Canadian Psychiatric Risk and Outcome Study

The primary study aims are to determine the clinical, behavioural and social predictors of SMI development in youth, and to investigate whether neuroimaging can distinguish youth who will develop SMI from those who will not. The study's sec

Calgary, Alberta, Canada+1 moreView details
RecruitingPhase 1

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists

n this pharmacokinetic/pharmacodynamic modelling study we will determine the ability of intranasal and intravenous naloxone and intravenous nalmefene to reverse opioid (fentanyl and sufentanil)- induced respiratory depression in healthy vol

Leiden, South Holland, NetherlandsView details
Active, not recruiting

Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)

To determine associations between dietary factors and risk of major chronic diseases and their risk factors

Multiple locationsView details
Recruiting

Depression and Driving

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

St Louis, Missouri, United StatesView details
TerminatedPhase 4

Predicting SSRI Efficacy in Veterans With PTSD

This is a research study to examine the effectiveness of a brief screening method that may predict which people with posttraumatic stress disorder (PTSD) or depression are most likely to show a positive response to selective serotonin reupt

Boston, Massachusetts, United States+1 moreView details
CompletedN/A

CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients

The aim of the study is to compare the effect of group-cognitive-behavioral therapy (CBT)versus treatment as usual with the selective serotonin reuptake inhibitor sertraline, in patients with diagnosis of temporal lobe epilepsy (TLE) and de

México, D.f., MexicoView details
CompletedN/A

Non-pharmacological Mitigation of Psoriasis

In the past few years, research has provided evidence for a possibility of dampening immune system by one's will after undergoing a specific training program. Aim of this study was to verity the efficacy in affecting both mind and body by a

Lodz, Łódź Voivodeship, PolandView details
UnknownN/A

Be a Mom: Effectiveness of a Web-based Preventive Intervention for Postpartum Depression

The main goal of the research is to apply and evaluate the web-based preventive intervention (the Be a Mom program), in terms of its efficacy, acceptability and feasibility (user's adherence, dropout), and user's satisfaction. Prior to the

Coimbra, PortugalView details
CompletedN/A

The Norwegian Stepped-Care TF-CBT Study

Every day, a significant number of children and young people in Norway experience violence, abuse, or other potentially traumatizing events. These children are at risk of developing serious health problems such as post-traumatic stress diso

Oslo, NorwayView details
WithdrawnN/A

The 28 Day Challenge

The purpose of this study is to determine how a 28 Day Challenge influences mental health and well-being. This is a blinded study.

Stanford, California, United StatesView details
CompletedN/A

Emotional Intelligence Program for Adolescents With Antisocial Behavior (DYNAMIS)

This study assessed the effectiveness of an emotional intelligence program based on the Salovey and Mayer model among adolescents exhibiting antisocial behavior. A quasi-experimental design was employed, involving 231 Colombian adolescent o

Cali, Valle del Cauca Department, ColombiaView details
CompletedN/A

Online Program to Reduce Depression in MS

This is an international, multicenter, randomized controlled trial of an internet-based CBT intervention for depression (Deprexis) conducted in five MS centers in the US and Germany. The trial consists of a three-arm primary trial phase and

Los Angeles, California, United States+4 moreView details
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