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Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

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UnknownN/A

Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer

Based on evidence that radiation-induced damage to the hippocampus plays a considerable role in neurocognitive decline after cranial irradiation, hippocampal-sparing whole brain radiation therapy (HS-WBRT) has been proposed. This study will

Beijing, Beijing Municipality, ChinaView details
Completed

Understanding Patient Perspectives on the Risks of Ionizing Radiation Used for Medical Imaging

Risks from imaging-related radiation exposure have become a popular topic in the media. Because these tests are commonly applied to patients at a cancer center, it is important to understand what patients know, how they feel about what they

New York, New York, United StatesView details
TerminatedPhase 2

Fluorescence-guided Resection in Breast Cancer

This is an explorative phase II study to investigate the suitability of PD L 506 in the specific intra-operative detection of breast tumour tissue.

Munich, GermanyView details
CompletedPhase 2

Pilot Indocyanine Green Imaging for Mapping of Arm Draining Lymphatics & Nodes in Breast Cancer

The purpose of this study is to determine if Indocyanine Green (IC-GREEN) is comparable to isosulfan blue (IS-BLUE) in the identification of arm lymphatics and arm-draining nodes during nodal staging procedures in breast cancer.

Stanford, California, United StatesView details
RecruitingPhase 3

A Study of Dato-DXd in Inoperable or Metastatic Hormone Receptor-positive, HER2 IHC 0 Breast Cancer

A study to assess the efficacy and safety of Dato-DXd in the pre-chemotherapy setting for patients with metastatic HR-positive, HER2 IHC 0 breast cancer.

Largo, Florida, United States+39 moreView details
CompletedPhase 1

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

The primary purpose of this study is to evaluate the safety, side effects, and dosage for Motexafin Gadolinium given with the chemotherapy drug docetaxel to patients with advanced cancers. Secondly, tumor response to the combined treatment,

Pittsburgh, Pennsylvania, United StatesView details
CompletedN/A

Locoregional Blocks for Breast Cancer Surgeries

Breast surgeries are common operative procedures that require appropriate postoperative analgesia.

Cairo, EgyptView details
CompletedN/A

Entertainment Media to Deliver Educational Messages About Mammography in Saudi Arabia

This clinical trial aims to test if Elissa's Entertainment-Education (EE) song can influence Saudi females' intention to perform breast cancer early screening via mammogram.

Richmond, Virginia, United StatesView details
Active, not recruitingPhase 3

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

The study will evaluate the safety and efficacy of datopotamab deruxtecan (also known as Dato-DXd, DS-1062a), when compared with Investigator's choice of standard of care single-agent chemotherapy (eribulin, capecitabine, vinorelbine, or ge

Duarte, California, United States+166 moreView details
UnknownPhase 3

Utidelone in Combination With AC Versus Docetaxel in Combination With AC for Neoadjuvant Chemotherapy in Patients With HER2-negative Breast Cancer

The purpose of this clinical trial is to evaluate the efficacy and safety of Utidelone plus AC versus Docetaxel plus AC as neoadjuvant chemotherapy in high-risk HER2-negative early-stage or locally advanced breast cancer. In this phase III,

Shanghai, ChinaView details
Recruiting

Novel Body Composition Measurements in Association With Outcomes of Breast Reconstruction Reconstruction

This study compares measurements of body composition to outcomes of breast reconstruction.

San Francisco, California, United StatesView details
Unknown

Female Sexual Dysfunction in Breast Cancer Patients

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females world wide. breast cancer alone accounts for 25% of all cancer cases and 15% of all cancer deaths among females.

Multiple locationsView details
CompletedPhase 1 / Phase 2

To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

This is a Phase Ib/II, multicenter, open-label study to evaluate the safety and preliminary efficacy of TT-00420 tablet, as monotherapy or in combination regimens, in patients with advanced solid tumors (solid tumor, BTC and TNBC).

Wuhu, Anhui, China+8 moreView details
Unknown

CARDIOCARE Prospective Clinical Study

This is a prospective observational study to refine and validate risk stratification algorithms aimed at identifying elderly patients at higher risk of developing cardiotoxicity (us-ing risk factors and potential blood and stool biomarkers)

Milan, ItalyView details
CompletedPhase 2

Comparison of TP and TAC Regimens in Neoadjuvant Treatment of TNBC

Previous studies have shown that TNBC is sensitive to DNA crosslinking-related chemotherapeutic drugs such as platinum. However, there is a lack of large sample prospective clinical data to compare the efficacy of TP and EC-T / TEC regimen

Zhengzhou, Henan, ChinaView details
UnknownPhase 4

A Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients With Taxane-Pretreated Recurrent Breast Cancer

The purpose of this study is to evaluate the response rate in patients with taxane-pretreated recurrent breast cancer receiving paclitaxel loaded polymeric micelle (Genexol-PM).

Seoul, South KoreaView details
RecruitingN/A

The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) 15 months after randomization (and there

New Haven, Connecticut, United States+35 moreView details
CompletedPhase 2

Gemcitabine Plus Cisplatin Single Dose Versus Split Dose in the Treatment of Patients With Locally Advanced or Metastatic Breast Cancer After Failure of Anthracyclines and/or Taxanes

This is an open label, two arms, randomized, unblinded phase 2 study in patients with locally advanced or metastatic breast cancer who have been previously treated with anthracycline with/without taxane based regimen in the adjuvant/neoadju

Jeddah, Saudi ArabiaView details
CompletedN/A

Meditation and Cancer, Pilot Feasibility Study (MAEva Pilot Study)

MAEVA, which stands for Meditation, Acceptance and Commitment towards Values, is an open and circular program, made up of 3 themed sessions, following a weekly rhythm. It is proposed here to study this program over a period of 3 months, whi

Vandœuvre-lès-Nancy, FranceView details
RecruitingN/A

A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer

The goal of this interventional study is to to evaluate the effectiveness and acceptability of a focused upper body massage when offered after radiation treatments to participants diagnosed with breast cancer. Given the prevalence of muscul

Columbus, Ohio, United StatesView details
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