TrialFind
SearchAbout
Saved trials

Filters

Sort by

Recruitment

Status

Phase

Age group

TrialFind

Making clinical research accessible to everyone. Search 500,000+ trials in plain English.

NavigationHomeSearch TrialsAboutSaved Trials
Data & LegalClinicalTrials.govPrivacyRegulatory infoContact

© 2025 TrialFind. Data sourced from ClinicalTrials.gov. Always consult a healthcare provider before enrolling.

Not yet recruitingPhase 2

Glymphatic Function TMS Study

The purpose of this study is to use transcranial magnetic stimulation (TMS) in older adults to impact the glymphatic system. The glymphatic system is a brain-wide clearance pathway that plays a crucial role in removing dysfunctional protein

Multiple locations
View details
Completed

Alzheimer's Family Research

This is a research study about how family members make research participation decisions for a relative with Alzheimer's or a related dementia. The purpose of this study is to learn more about how proxies (the family member who makes decisio

San Francisco, California, United States
View details
Load more trials
Unknown

Working Memory Functioning in Alzheimer's Disease and Vascular Dementia

The aim of the present study is to investigate potential cognitive mechanisms contributing to working memory impairment in Alzheimer's disease and vascular dementia. The investigators consider a new hypothesis suggesting that difficulties i

Multiple locations
View details
RecruitingN/A

Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia

This current translational project, funded by NIH, aims to better understand the impact of various signal modification strategies for older adults with Alzheimer's dementia and its potential precursor, known as amnestic mild cognitive impai

Chicago, Illinois, United States+1 more
View details
UnknownPhase 4

Donepezil and Memantine in Moderate to Severe Alzheimer's Disease

The trial will examine whether pharmacological treatment with donepezil, memantine or combination of memantine and donepezil is any better than a placebo (dummy) treatment in people with Alzheimer's disease who have reached the moderate to

London, United Kingdom
View details
RecruitingPhase 1 / Phase 2

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

This is a Phase 1/2 study to evaluate the safety and tolerability of 18F-OP-801 in subjects with ALS, AD, MS, PD and age-matched HVs. 18F-OP-801 is intended as a biomarker for PET imaging of activated microglia and macrophages in regions of

San Francisco, California, United States+2 more
View details
TerminatedPhase 3

A Study of Galantamine Used to Treat Patients With Mild to Moderate Alzheimer's Disease

The purpose of this study is to compare the effectiveness and safety of 2 years of treatment with galantamine as compared with placebo of patients who have mild to moderately severe Alzheimer's disease (AD).

Hradec Králové, Czechia+94 more
View details
Recruiting

Alzheimer's Disease Genetics Study

The purpose of the Alzheimer's Disease Genetics Study is to identify the genes that are responsible for causing Alzheimer's Disease (AD). One of the ways in which the risk factor genes for late onset AD can be investigated is by identifying

Nationwide, Indiana, United States
View details
CompletedPhase 2

Biomarker Effects of ALZ-801 in APOE4 Carriers With Early Alzheimer's Disease

The study will investigate the effects of oral ALZ-801, in subjects with Early AD who have the APOE4/4 or APOE3/4 genotype, on the biomarkers of core AD pathology. The objectives of this study include determining the efficacy and safety/tol

Brno, Czechia+5 more
View details
UnknownN/A

The Relationship Between Obstructive Sleep Apnea and Alzheimer's Disease: Evidence and Effectiveness

The research plan to enroll 15 simple snoring patients (apnea/hypopnea \<5, control group), 30 severe OSA patients (apnea/hypopnea \>30, treatment group), and 15 mild cognitive impairment patients (comparative group). All patients complete

Taoyuan, Taiwan
View details
CompletedPhase 4

A 24 Week, Multicenter, Open, Evaluation of the Clinical Effectiveness of the Once-daily 10 cm^2 Rivastigmine Patch Formulation in Patients With Probable Alzheimer's Disease (EXTRA)

This study is designed to confirm the efficacy, the tolerability, the patient compliance and the caregiver satisfaction with rivastigmine target patch size 10 cm\^2 in patients with probable Alzheimer's Disease (Mini-Mental State Examinatio

Rueil-Malmaison, France
View details
UnknownN/A

Continuous Arterial Spin Labeling (CASL) MRI for Monitoring and Prediction of Drug Therapy in Alzheimers Disease (AD)

Examination of the correlation between the cerebral bloodflow and the clinical change under treatment with Reminyl retard® and the prediction of clinical change by measuring the cerebral bloodflow in patients with mild to moderate Alzheimer

Bonn, Germany
View details
CompletedPhase 1

Study With Lu AF87908 in Healthy Participants and Participants With Alzheimer's Disease

The purpose of this study is to investigate the safety of a single dose of Lu AF87908, how well it is tolerated and what the body does to the drug in healthy participants and participants with Alzheimer's disease.

Glendale, California, United States+5 more
View details
CompletedN/A

Targeting Default Mode Network Dysfunction in Persons At Risk of Alzheimer's Disease with Non-invasive Techniques

Default mode network (DMN) dysfunction is a well-established feature of Alzheimer's Disease (AD) and is already present in preclinical stages and in subjects at risk for AD, thus offering a potential target for early intervention. Non-invas

Brescia, Brescia, Italy
View details
CompletedPhase 1

A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired Subjects

This study will test if two flortaucipir PET scans up to 4 weeks apart in healthy volunteers, MCI and AD subjects provide the same results.

Newport Beach, California, United States+1 more
View details
UnknownN/A

Multimodal Imaging Study on Physical Activity in Patients With Alzheimer's Disease

This study aims to gain a better understanding of metabolic early changes in neurodegenerative diseases, in order to enable new diagnostic and therapeutic approaches in the future. Further, it aims to identify specific movement-induced chan

Aachen, North Rhine-Westphalia, Germany
View details
CompletedN/A

Partnered Rhythmic Rehabilitation in Prodromal Alzheimer's Disease

Interventions that affect many different aspects of human ability rather than just one aspect of human health are more likely to be successful in preventing and treating Alzheimer's disease (AD). Functional decline in AD is severely impacte

Atlanta, Georgia, United States
View details
Completed

Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Clinical Safety and Effectiveness in Patients With Alzheimer's Disease

To investigate the clinical safety and effectiveness of donepezil hydrochloride administration in patients with mild or moderate Alzheimer's Disease

Anjo, Aichi-ken, Japan+105 more
View details
RecruitingN/A

Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function

This randomized study tests whether a new multicomponent Positive Psychology program can improve cognition and wellbeing in older adults at the earliest stages of dementia-related decline. About 128 participants with Subjective Cognitive De

Thessaloniki, Greece
View details
Not yet recruiting

A Pilot Study of Deep Cervical Lymphatic-venous Anastomosis in the Treatment of Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent form of dementia, affecting 3-4% of the population over a lifetime. It's characterized by abnormal Amyloid-beta (Aβ) and tau protein expression and accumulation in the central nervous system, l

Multiple locations
View details